Team:Dundee

Dundee 2016

University of Dundee iGEM

BactiFeed

University of Dundee iGEM 2016

"BactiFeed is All You Need"

Abstract

Antimicrobial resistance will kill between 14 million and 444 million people by 2050, according to the World Health Organisation. Antibiotics are used extensively in livestock to combat infection; this is a massive contributor to the growing problem of antibacterial resistance.

An alternative treatment for livestock is needed if we are to preserve antibiotics for medicinal use. To combat this, we are Fighting Bacterial Infections by modifying bacteriocins through introducing novel toxic domains. We are engineering non-pathogenic E. coli to produce bacteriocins in response to conditions in the GI tract that will kill pathogenic strains of E. coli and similar bacteria such as Salmonella. We believe our GM bacteria can be used in an animal feed, a ‘BactiFeed’, to tackle common bacterial infections in livestock, decrease unnecessary antibiotic usage and reduce the development of antibacterial resistance.

Learn about Bactifeed

Our video takes you on a tour of the Bactifeed labs; there you will meet our CEO Charles Bacti, our dedicated scientists and some of our supporting staff in the modelling and design departments. You shall also learn of our concept and what Team Dundee 2016 is all about - enjoy!

Watch the Bactifeed commercial!