Team:SYSU-Software/Engagement

SYSU-Software:Project

ENGAGEMENT

  • Public Engagement had occupied the largest segment of our Human Practice activities. We used other materi-

  • als and video games to illustrate the function of standard elements in synthetic biology; we present small

  • lectures to senior high school students and freshmen, introducing main principles and sharing our project

  • ideas, discussing safety and ethics problems.

Function Illustration

  • Garden party for introduction of synbio to the public

  •    We, together with SYSU-CHINA, held a parade in the campus to introduce synthetic biology to the public. Our

  • audiences were all enthusiastic, including not only students from life sciences and many other majors, but teachers of

  • different backgrounds. Also, some residents and tourists showed an enormous interest in our garden party. This time,

  • we divided our parade into 2 parts. First, you could splice a fundamental Circuit Project in the “Splice a Circuit” part.

  • What you need to do is to put the genetic parts in the right orders to complete a circuit. By using the electronic bricks

  • to symbolize the different parts in synbio, we managed to introduce the four fundamental parts to the public by visual-

  • ized approaches. If a circuit is completed correctly, a light bulb which symbolizing a certain functional CDS would be

  • lightened. By turning the microcosmic process into the visible and operable way, we successfully attracted many partici-

  • pants to get involved in our game, especially some kids and teenagers who got the pure pleasure of scientific research.

  • “This is absolutely the most exciting game I’ve ever played. “It inspires me to take more time in biology study as a stu-

  • dent of senior high”, said by one student.

  •    As to the second part “Design a Circuit”, you must use the synbio knowledge you’ve already learned in the first

  • game and your imagination to design a much more complicated circuit. Made up of more than twenty biobricks and re-

  • lated to Toggle Switch, the circuit was so hard that even some of our team members were stumped. However, to our

  • surprise, some participants did finish the circuit with least effort, including a pupil. During this garden party, we’ve seen

  • more and more Chinese teenagers devoting themselves in the joy of life sciences, and our team will try our best to

  • make contributions to spreading this joy to the public without any doubt.

  • Biological Contest in Modeling

  •    As a good instance in the collaboration between outstanding universities in Guangdong Province, the “Bio-5-Talk” is

  • a series of activities which really make difference in developing communications among college students in Guangdong.

  • The highlight during “Bio-5-Talk” is absolutely the Biological Contest in Modeling. This year the annual party attracted

  • 15 teams. By using fruits, styrofoam and other materials which are common in daily life, the participants are asked to

  • make a fabricated eukaryotic cell by hand. Our team used toothpicks to imitate the cytoskeleton together with plasti-

  • cine as the organelles, making a patterned and simple eukaryotic cell. We managed to use the cell model to illustrate

  • the basic process of transcription and translation, together with the knowledge of synbio to the other teams. At the

  • same time, we surely made some other participants interested in synthetic biology.

  •    Even in Biology Festival we used toy electronic components symbolizing the genetic circuits, some participants also

  • felt confused about synthetic systems and their function in reality because electric circuits also had slight differences

  • from genetic circuit. Thus we decided to develop a video game in which genetic circuits coming from real projects and

  • their parts are shown as those in SBOLv.

  •    Then Genexplorer came into being, in which the player can built a circuit following the order of parts shown in the

  • game, and all circuits were retrieved from eminent projects in previous competition. Target players of this game is

  • people who have not ever learned synthetic biology but have interests in it.

  •    We have promoter this to other iGEM teams, and the public in CCiC and High School Summer Camp, where

  • the attending students and teams showed great interest in this simple and enjoyable game. With their suggestions, we

  • developed a hard mode later. For more details or if you want to download this game, please click the link.

  • We are SYSU-Software. We are very grateful for everyone's hard work.

Introduction, Sharing and Discussion

  • Presentation for High School Summer Camp

  •    During the summer vacation, School of Life Sciences, Sun Yat-sen University held a Summer Camp for high school

  • students in China, introducing biology related researches and activities to them. SYSU-Software also grasped this op-

  • portunity and attended to this camp, presenting an one-hour introduction about synthetic biology and iGEM competi-

  • tion to them.

  •    Considering what they have learnt in senior high school, we organized our presentation as a small lecture, from

  • DNA, RNA sequence and genetic engineering to the principles and target strata in synthetic biology. Our presentation

  • explained three main factors that led to success in synthetic biology: standardization, decoupling and abstraction. We

  • emphasized the importance of standardization, which enabled the biologists to create circuits having specific functions

  • with “Bio-bricks” like building constructions with bricks. This principle was also most familiar with these students be-

  • cause they had learnt something about genetic biology, and noticed the deficiencies in digested operation if restriction.

  • sites unspecific between gene parts. Although the other two principles, decoupling and abstraction, was hard to image

  • their roles in synthetic biology for these students, we believed their main idea would help students when they had to

  • face some complex problems in the future.

  •    We also introduced the target strata in synthetic biology, including sequence, part, device and system. From se-

  • quence to higher stratum, we thoroughly explained how a intact synthetic system form, and mentioned standardization

  • again. At last, we presented a brief introduction on iGEM competition, including its history, tracks and awards. We also

  • introduced the software track and what we have done in this track.

  •    After the presentation, many students showed their interests in synthetic biology and iGEM. One of them even said

  • that he was excited because he had played LEGO for years but had never imaged functions in creatures can be built

  • like the toy bricks, and he wanted to know more about synthetic biology and iGEM.

  • Mini lecture to 2016 freshmen

  •    We presented a mini lecture for 2016 freshmen shortly after the start of the new semester, in which we introduced

  • iGEM competition, synthetic biology, our team project as well as our Human Practice activities, especially the game

  • Genexplorer. We exemplified GFP to illustrate four basic elements in synthetic biology and how they work in real bac-

  • terium.

  •    After the lecture, with the freshmen, we also discussed the biosafety and ethics problems that brought from syn-

  • thetic biology. The freshmen raised some problems that our project should concern or may ignore.