Oxford iGEM 2015

Implemented kill switches: 3

Kill Switch 1

Class

# Format: # Write how you would classify them.

Toxins

Name Number Comment
CASP8 caspase

Antagonists

Name Number Comment

Topology

Kill Switch topology

Parts

Name Number Comment
Inducible Promotor induced by valine and AI2
lacI LacI protein
lac promotor repressed upon binding of LacI
CASP8 caspase protein involved in apoptosis

Kill Switch 2

Class

# Format: # Write how you would classify them.

Toxins

Name Number Comment
CASP8 caspase

Antagonists

Name Number Comment

Topology

Kill Switch topology

Parts

Name Number Comment
Inducible Promotor induced by valine and AI2
lacI LacI protein
lac promotor repressed upon binding of LacI
CASP8 caspase protein involved in apoptosis

Kill Switch 3

Class

# Format: # Write how you would classify them.

Toxins

Name Number Comment
CASP8 caspase

Antagonists

Name Number Comment

Topology

Kill Switch topology

Parts

Name Number Comment
Hypothetical Promotor induced by valine and AI2
lacI LacI protein
lac promotor repressed upon binding of LacI
CASP8 caspase protein involved in apoptosis