Difference between revisions of "Team:IIT-Madras"

 
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<span style="font-family: bold; font-size: 30px; letter-spacing: 6px; color: #00ae93; font-weight: 200;"> Team IIT Madras </span><br><br>
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<span style="font-family: light; font-size: 2.5em; letter-spacing: 6px; color: #00ae93;"> IIT Madras</span><br><br>
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Developing novel methods and tools to understand and engineer biological systems <br><br>
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Analyse, decipher and control cellular computation. <br><br>
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<span style="font-family: bold; font-size: 20px; letter-spacing: 1px; color: #ffffff; font-weight: 200; padding-bottom: 20px;"> NOISE IN DEVICES </span><br><br>
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<img src="https://static.igem.org/mediawiki/2016/d/d1/Iitm_noise.png" height=125>
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<li style="display: inline-block; margin: 40px; background: #181818; border: none; min-width: 269px; max-width: 270px; text-align center; border-radius: 3px; box-shadow: 1px 2px 4px rgba(24,24,24,0.5); font-family: regular; padding: 20px; font-size: 18px; color: white; vertical-align: top; min-height: 350px;">
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<span style="font-family: bold; font-size: 20px; letter-spacing: 1px; color: #ffffff; font-weight: 200; padding-bottom: 20px;"> CRISPR efficiency  </span><br><br>
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Measurement of efficiency of sgRNAs which are specific to RFP, kanamycin resistance and chloramphenicol resistance genes.  
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Exploring noise in devices to understand and predict their behavior. Intrinsic noise in devices seems to increase with increase in protein expression levels irrespective of constituent parts e.g. different RBSs and promoters.
 
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        <a style="text-decoration:none;" target="_" href="https://2016.igem.org/Team:IIT-Madras/Description#RIBOS">
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<span style="font-family: bold; font-size: 20px; letter-spacing: 1px; color: #ffffff; font-weight: 200; padding-bottom: 20px;"> RIBOS </span><br><br>
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                <span style="font-family: bold; font-size: 20px; letter-spacing: 1px; color: #ffffff; font-weight: 200;"> RIBOS </span><br><br>
 
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Design and development of RNA Inducible Boolean-like Output Switches(RIBOS) for better control over gene expression.
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Designed and experimentally validated the functionality of RNA Inducible Boolean-like Output Switches (RIBOS) for better control over gene expression. Now, get RIBOS devices for your own genes.
 
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<a  style="text-decoration:none;" target="_" href="https://2016.igem.org/Team:IIT-Madras/Model">
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<span style="font-family: regular; font-size: 20px; letter-spacing: 1px; color: #ffffff; font-weight: 200; padding-bottom: 20px;"> NOISE IN DEVICES </span><br><br>
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<img src="https://static.igem.org/mediawiki/2016/d/d1/Iitm_noise.png" height=125>
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                      <span style="font-family: bold; font-size: 20px; letter-spacing: 1px; color: #ffffff; font-weight: 200; padding-bottom: 20px;"> TRANSLATION SCORE CALCULATOR </span><br><br>
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Exploring noise in complex devices and modelling it is a product of noises from individual parts.<br>
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Designed and validated an empirical model to predict the variations in translational score of RBS parts. Now, you can get protein expression levels for your own expression system!
 
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{{IIT-Madras-footer/CSS}}
 
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Latest revision as of 19:14, 19 October 2016


  • IIT Madras

    Analyse, decipher and control cellular computation.

NOISE IN DEVICES


Exploring noise in devices to understand and predict their behavior. Intrinsic noise in devices seems to increase with increase in protein expression levels irrespective of constituent parts e.g. different RBSs and promoters.
RIBOS


Designed and experimentally validated the functionality of RNA Inducible Boolean-like Output Switches (RIBOS) for better control over gene expression. Now, get RIBOS devices for your own genes.
TRANSLATION SCORE CALCULATOR


Designed and validated an empirical model to predict the variations in translational score of RBS parts. Now, you can get protein expression levels for your own expression system!