Team:UCL/Human Practices

The experts

We have been talking to researchers that are in the ageing field

Religion, Synthetic Biology and Ageing

We have been talking to religious leaders and religious members of the public to find out what they they think about our project and synthetic biology and to find an answer to whether religion actually acts as a barrier to the development of synthetic biology.

Public Engagement/General Public

We also wanted to find out what the general public think of our project and synthetic biology. We conducted surveys, went to the streets of London and many more activities in order to get a well rounded view.

Ageing and art

Sue and Diane art group

Industry

General public opinion

  1. What are the views of the younger generation?
  2. What are the views of the middle aged population?
  3. What are the views of the elderly population
How do these views differ from each other? Who is our target audience? Whats our motivation?

Resources for the younger generation

In response to the survey, we wanted to make synthetic biology and iGEM more accessible to the younger generation, and the rest of the public. So we decided that we wanted to make some resources for young children about our project, synthetic biology and ideas around synthetic biology. We have this document translated in English, German, French, Farsi, Spanish and Mandarin.

pdf file

Our iGEM blog

We also wanted the general public to know about our project and iGEM so we decided to make a blog highlighting our general experiences as we go along this iGEM journey! We are also working on posting some tips for future GEM teams, based on what we are learning as we go through the process.

The Blog link: http://ucligem2016.wix.com/ucligem2016

Our App

As mobile phones are becoming increasing part of our lives, we thought that developing an app may be a great way to get more people more aware of synthetic biology. We have decided to create a game that works by getting users to create certain biobricks, where the gene of interest will only complete the biobrick if the plasmid backbone is cut with the correct restriction enzymes. We want to make it as user friendly as possible and we are hoping to integrate our project and iGEM into the app as well.

Press release

We were able make more people aware of our project by getting our project advertised through the UCL website (Biochemical engineering News section). We are also working on getting the project advertised on the UCL newsletter (myUCL).

Workshop with the younger generation

We were able to inspire the next generation of scientists, engineers, conputer scientists and phycolgists through a workshop. We told them what synthetic biology is, our project, asked them what their perception of the elderly is and ran some fun activities. We also gave the students a chance to have some lab experience.

We asked the children to draw what they think of when I said AGEING

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We then asked the children to draw what they envision themselves looking like when they are 65 years old (the age when you are considered as elderly)

Also follow our vlog where we upload fun videos of the team members and vlog throughout our iGEM journey

Elderly opinion

Tea with the elderly on Saturday 16th July. Chichi was able to attend the tea session where she was able to ask some of the elderly what they thought about our idea and synthetic biology.

Talk to Dementia patients- Weinberg-Rauhes Haus

Since the age of 14 I have been regularly exposed to the beautiful and perilous aspects of growing old and taking care of the elderly. I started out by occasionally helping out in a dementia home in Hamburg with a family friend who works with therapy dogs for the elderly. Then right after graduating high school I worked in Alzheimer’s research at Roche for 9 months and through that I got to meet a lot of people very passionate about this, whilst also getting a good insight into the pharma side of things.

It has been two years since my work at Roche and I’ve spent my other summers either working in an office or now on iGEM. Although our project is about ageing, I haven’t been thrown into the deep end of dementia research and care for a while. Precisely until I was back at the dementia home in Hamburg this past week, this time with the purpose of getting the opinions of the elderly about our project and their life in general. I got to speak to a few people individually and then also two groups of people, everyone with varying forms of dementia: from very light Alzheimer’s, which you wouldn't be able to tell, to the late stages, which are almost incomprehensible. Overall these experiences were enlightening, inspiring and motivating to do more research and help but simultaneously the potential realities of the future are distressing.

Over the next few weeks we will be publishing the stories of the people I got to speak to and the impressions and experiences I gained from the group sessions.

Week long outreach workshops with year 12 students at the sutton trust summer school Monday 8th -12th July

Outreach activity workshop with year 12 students at the sutton trust summer school Thursday 28th July

UCL iGEM does Outreach:

Last Thursday Michelle, Amandeep & Abbie presented to a group of year 12 students about synthetic biology, iGEM and ageing (and even got invited back to present later this month)! We encouraged discussion throughout the lecture and it was great to teach them a little bit too.

We then proceeded to have two debates: one focussing on ageing, another on synthetic biology.

The arguments were eloquent, well thought through and focussed on aspects such as the economic, ethical and even emotional impact of this research. The debate was particularly poignant at times and the students all had their own opinions which we encouraged the discussion of. We were not only impressed, but inspired by their enthusiasm and the feedback we received. Especially now some of the students want to get involved with iGEM and even study biochemical engineering- a degree they previously didn't know existed.

Outreach activity workshop with year 8 students at the sutton trust summer school Friday 29th July

Friday was another day of presenting for us 3- this time to year 8 students - we gave them an insight into ageing in London and again encouraged participation. After our talk we again set up a debate in which the students represented one of the following stakeholders:

'Business person wanting to build a gym', 'scientist wanting to build an ageing research institution', 'doctor wanting to build a walk-in clinic' and 'the council wanting to build a community centre'.

Again, great arguments were constructed which considered the negatives of the other parties as well as the strengths of their own. They considered the different types of job prospects, ethics and short vs long term investments. We were particularly pleased with the vote outcome in which the students favoured a research institution to be built.

UCL iGEM x Sutton Trust summer school - biosciences stream

This summer school is based at UCL and formed part of our outreach activities since it is aimed at students from widening participation backgrounds. Abbie worked closely with the students and lead a group of 5, year 12 students.

This involved demonstrating various lab activities from basic pipetting to performing restriction digests and running gel electrophoresis. We also performed an activity which looked at the bacteria on skin before and after washing hands, the effectiveness of chemicals on killing bacteria and even gram stained these, looking under them at a microscope. A lot of the experiments were new to the students so it was essential to explain the techniques and assist throughout.

It was also an opportunity to give advice about university and share our own personal experiences.

Amandeep and Abbie also gave a lecture on iGEM, synthetic biology and ageing. Afterwards we ran a workshop and debate with regards to synthetic biology and ageing research as before to the 30 students on the stream. We really enjoy this activity due to the consideration of ethics, economics and personal experiences.

Some highlights have been collated in the video.

UCL iGEM x David Kurten (London Assembly)

We wanted to understand where our project fits in with public policy and are trying to gain a well-rounded view. To do this we met with David Kurten, a UKIP member of the London Assembly. After explaining our project we went onto discuss what priorities the elderly population has, the public perception of GM and the effect of Brexit on science research. Here is what we discovered:

  1. Science is ahead of politicians knowledge, similarly, legislation is slower than the rate of research. There is the potential therefore for research to accelerate without real consideration of the ethics. 

OUR SOLUTION: thoroughly discuss and explore the ethics of our project.
  2. Gene therapy Introducing something unnatural- genetically modifying human DNA. Again, sciences races ahead of legislation. Requires the Government of the day to be behind it for it to become law.

OUR SOLUTION: Talk with an MP about the process of legislation with regards to GM, synthetic biology and science research.
  3. Consent: this is important with regards to who will be affected.

OUR SOLUTION: Talk to lots of people to see if they would like to take a therapy/get in contact with those who already have.
  4. Vested interests: political and green and companies, research funding bodies.
Knowledge and transparency of information important.

OUR SOLUTION: Present our research with no bias and be transparent with results.
  5. What can we do to change public opinion? 
Existing propaganda has influenced the opinions of the public. There is a need of transparency. e.g. of labelling food.
  6. Semantics of GM vs synthetic biology ‘advancing progressing, doing science’ vs biotechnology, again has positive connotations.
  7. UKIP policy: look into what the science says. Allow research to happen on an objective basis as well as to ensure that large data sets are used.
  8. Loss of faith in scientists due to medias portrayal - faking data news story. Suggested that raw data directly to public to let them make own decisions. (we are aware this is ridiculous).
There is a need however for communicating the information without a bias. Media- sensationalism sells. Deeper level of understanding is needed. Currently a dumbing down of culture rather than this uplifting of culture.
  9. On Brexit. 20 billion to EU, 10 billion back, net fee of around 10 billion. A lot of EU funding is British money. Not going to effect the UK for funding (just missing out). Collaboration will continue- not dependent on EU dependent upon innovators and scientists regardless of EU. People that are involved. Long term- cutting out a layer of bureucracy- more efficient and less
  10. Medical without ethics, looks great. Changed DNA structure - lots of discussion is needed. Is this natural or not. Personal view- cautious, case by case basis. Not a fan of changing DNA, it’s evolved over time to how it is now. Short term benefits- what about the long term implications- they are unknown. Should we be doing this? ‘perfect super human race’ personally- should not be playing around of DNA. Taking ethics, morality and faith out of the question, we should do it. But adding these I think we shouldn’t.
  11. Ageing: unintended consequences of action. population increase/policy change- working longer, pension system would collapse. Increasing retirement age- public wouldn’t like it. political suicide. demographics of voters- older people vote more.

Synthetic biology showcase: Friday 16th July

Amandeep, Michelle and Abbie presented at the Annual Synthetic Biology Showcase at UCL. This was a unique opportunity to share our project with leading synthetic biology researchers, shape our newer ideas as well as to discuss the ethics of our project.

Human Practices Hub.

Note

You must fill out this page in order to be considered for all awards for Human Practices:

  • Human Practices silver medal criterion
  • Human Practices gold medal criterion
  • Best Integrated Human Practices award
  • Best Education and Public Engagement award
Some Human Practices topic areas
  • Philosophy
  • Public Engagement / Dialogue
  • Education
  • Product Design
  • Scale-Up and Deployment Issues
  • Environmental Impact
  • Ethics
  • Safety
  • Security
  • Public Policy
  • Law and Regulation
  • Risk Assessment
What should we write about on this page?

On this page, you should write about the Human Practices topics you considered in your project, and document any special activities you did (such as visiting experts, talking to lawmakers, or doing public engagement).

Inspiration

Read what other teams have done: