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Revision as of 21:49, 5 October 2016

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UCL iGEM 2016 | BioSynthAge

Lungs: Superoxide Dismutase Gene therapy

Over expression of antioxidants that break down toxic reactive oxidative species into less harmful hydrogen peroxide. Read more about our novel synthetic biology approach to the prevention of age-related diseases to the lungs.

Ageing of lungs: the problem

Vital for respiration, the lungs are responsible for keeping us alive. As we age, our lungs become less effective at carrying out their function and these age-related changes contribute somewhat to an older person's reduced ability to do vigorous exercise, especially intense aerobic exercise. More specifically, the effects of aging on the respiratory system are similar to those that occur in other systems: there is a decrease in peak airflow and gas exchange and a decline in the effectiveness of lung defence mechanisms.