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| − | {{Team:Tokyo Tech/template2016}}
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| − | <html>
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| − | <head>
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| − | <style type="text/css">
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| − | <!--
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| − | /********************** All style of this page ************************/
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| − | body{
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| − | background: #052d5d;
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| − | background-image: url("https://static.igem.org/mediawiki/2016/8/83/Tokyo_Tech_Background.png");
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| − | background-size: 75%;
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| − | // background-size: 60%;
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| − | }
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| − | #globalWrapper, #content{
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| − | background: transparent;
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| − | }
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| − | #content{
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| − | // background: #052d5d;
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| − | // background-image: url("https://static.igem.org/mediawiki/2016/8/83/Tokyo_Tech_Background.png");
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| − | margin: 0 auto;
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| − | border: 0px solid #052d5d;
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| − | }
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| − | /**********************************************************************/
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| − | #main_contents{
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| − | margin: 0 auto;
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| − | width: 90%;
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| − | min-width: 880px;
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| − | max-width: 1100px;
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| − | // background: #052d5d;
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| − | // border:1px solid #052d5d;
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| − | }
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| − | .container{
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| − | margin: 5px auto;
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| − | background: #ffffff;
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| − | }
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| − | .container_top h1{
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| − | margin-top: 1px;
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| − | font-size: 36px;
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| − | }
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| − | .container_header{
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| − | background: #ffffff;
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| − | text-align: center;
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| − | }
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| − | .container_header span{
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| − | border-bottom: 2px solid #052d5d;
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| − | }
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| − | .container_contents{
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| − | line-height: 1.5em;
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| − | width: 800px;
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| − | margin: 0 auto;
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| − | padding-bottom: 10px;
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| − | }
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| − | .normal_text{
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| − | font-size: 18px;
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| − | text-indent: 18px;
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| − | text-align: justify;
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| − | // padding: 18px;
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| − | font-family: 'Century', serif;
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| − | }
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| − | .on{
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| − | display: block;
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| − | -webkit-transiton: all 0.6s ease;
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| − | transition: all 0.6s ease;
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| − | }
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| − | .off{
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| − | display: none;
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| − | -webkit-transiton: all 0.6s ease;
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| − | transition: all 0.6s ease;
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| − | }
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| − | --></style>
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| − | </head>
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| − | <body>
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| − | <div id="main_contents">
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| − | <div id="page_header" class="container container_top">
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| − | <h1 align="center">Modeling Overview</h1>
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| − | </div><!-- /page_header -->
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| − | <div id="overview" class="container">
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| − | <div id="overview_header" class="container_header">
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| − | <h2><span>OVERVIEW</span></h2>
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| − | </div><!-- /overview_header -->
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| − | <div id="overview_contents" class="container_contents">
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| − | <p class="normal_text">To reproduce ”Snow White”, we have designed the cell-cell communication system with improved or characterized parts and collect data from exhaustive experiments.
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| − | However, since our gene circuits are so complex that we couldn’t predict whether <span style="font-style: italic;">E. coli</span> can play the story, we constructed the mathematical model and simulate them.
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| − | This simulation successfully contributed to give the suggestions to wet lab experiments and confirm the feasibility of our system.
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| − | Also, in order to utilize TA system, we developed the software in Java for adjusting the number of ACA sequences, which MazF dimer recognizes and cleaves in mRNAs.</p>
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| − | </div><!-- /overview_contents -->
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| − | </div><!-- /overview -->
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| − | <div id="mathematical_model" class="container">
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| − | <div id="mathematical_model_header" class="container_header">
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| − | <h2><span>MATHEMATICAL MODEL</span></h2>
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| − | </div><!-- /mathematical_model_header -->
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| − | <div id="mathematical_model_contents" class="container_contents">
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| − | <p class="normal_text">To simulate our gene circuits, we developed an ordinary differential equation model.</p>
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| − | <p style="text-align:center;">[<a href="https://2016.igem.org/Team:Tokyo_Tech/Modeling_Details">Model Development</a>]</p>
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| − | <p class="normal_text" style="text-align:center;"><a href="javascript:void(0);" onClick="show('modelingDetail');" class="showHidden">Show expressions</a></p>
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| − | <div id="modelingDetail" class="off">隠しスペース</div>
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| − | </div><!-- /mathematical_model_contents -->
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| − | </div><!-- /mathematical_model -->
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| − | <div id="results" class="container">
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| − | <div id="results_header" class="container_header">
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| − | <h2><span>RESULTS OF SIMULATION</span></h2>
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| − | </div><!-- /results_header -->
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| − | <div id="results_contents" class="container_contents">
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| − | <p class="normal_text">Lastly we got and verified the desirable behavior of the fluorescence by modifying and improving them.
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| − | As described below, it is consistent with the development of story.</p>
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| − | </div><!-- /results_contents -->
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| − | </div><!-- /results -->
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| − | <div id="software" class="container container_bottom">
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| − | <div id="software_header" class="container_header">
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| − | <h2><span>SOFTWARE</span></h2>
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| − | </div><!-- /software_header -->
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| − | <div id="software_contents" class="container_contents">
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| − | <p class="normat_text">ACA Sequence: </p><form>
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| − |
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| − | </div><!-- /software_contents -->
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| − | </div><!-- /software -->
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| − | </div><!-- /main_contents -->
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| − | <script type="text/javascript">
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| − | function show(idName){
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| − | var elem = document.getElementById(idName);
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| − | if(elem.className === 'on'){
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| − | elem.className = 'off';
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| − | var elem2 = document.getElementsByClassName('showHidden');
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| − | elem2[0].textContent = 'Show expressions';
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| − | } else {
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| − | elem.className = 'on';
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| − | var elem2 = document.getElementsByClassName('showHidden');
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| − | elem2[0].textContent = 'Hide expressions';
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| − | }
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| − | }
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| − | </script>
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| − | </body>
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| − | </html>
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