Difference between revisions of "Team:Tokyo Tech/Modeling Overview"

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<h1 align="center">Modeling Overview</h1>
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<h2><span>OVERVIEW</span></h2>
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<p class="normal_text">To reproduce ”Snow White”, we have designed the cell-cell communication system with improved or characterized parts and collect data from exhaustive experiments.
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However, since our gene circuits are so complex that we couldn’t predict whether <span style="font-style: italic;">E. coli</span> can play the story, we constructed the mathematical model and simulate them.
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This simulation successfully contributed to give the suggestions to wet lab experiments and confirm the feasibility of our system.
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Also, in order to utilize TA system, we developed the software in Java for adjusting the number of ACA sequences, which MazF dimer recognizes and cleaves in mRNAs.</p>
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<h2><span>MATHEMATICAL MODEL</span></h2>
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<p class="normal_text">To simulate our gene circuits, we developed an ordinary differential equation model.</p>
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<p style="text-align:center;">[<a href="https://2016.igem.org/Team:Tokyo_Tech/Modeling_Details">Model Development</a>]</p>
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<h2><span>RESULTS OF SIMULATION</span></h2>
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<p class="normal_text">Lastly we got and verified the desirable behavior of the fluorescence by modifying and improving them.
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As described below, it is consistent with the development of story.</p>
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<h2><span>SOFTWARE</span></h2>
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<p class="normat_text">ACA Sequence: </p><form>
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Latest revision as of 10:34, 12 October 2016