Difference between revisions of "Team:Exeter/Integrated Practices"

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                 <p id="pp">Due to time restraints with our project we decided to focus on providing significant analysis on the kill switches individually, however advice from Markus Geshater of Synthase Limited indicating that multiple kill switches in one system would be unfeasible and the different systems would need to be truly orthogonal to be effective. He explained that if in an industrial setting your synthetic system is producing a protein, then having one or multiple kill switches that are reliant on protein production would reduce the efficiency of production of your desired protein. Furthermore these kill switches could potentially be circumvented by the overexpression of a useful enzyme that is being commercially produced. Consequently, we felt assured in dropping the idea of a multiple kill switch system, because, as our kill switches rely heavily on protein production, and we want to provide analysis for future teams wanting to use kill switches in the future, if their synthetic systems relied on protein production, then our kill switches would be unfeasible. Instead we looked to design three distinct kill switches to test the efficiency of enzymatic, metabolic and DNA degradating mechanisms</p>
 
                 <p id="pp">Due to time restraints with our project we decided to focus on providing significant analysis on the kill switches individually, however advice from Markus Geshater of Synthase Limited indicating that multiple kill switches in one system would be unfeasible and the different systems would need to be truly orthogonal to be effective. He explained that if in an industrial setting your synthetic system is producing a protein, then having one or multiple kill switches that are reliant on protein production would reduce the efficiency of production of your desired protein. Furthermore these kill switches could potentially be circumvented by the overexpression of a useful enzyme that is being commercially produced. Consequently, we felt assured in dropping the idea of a multiple kill switch system, because, as our kill switches rely heavily on protein production, and we want to provide analysis for future teams wanting to use kill switches in the future, if their synthetic systems relied on protein production, then our kill switches would be unfeasible. Instead we looked to design three distinct kill switches to test the efficiency of enzymatic, metabolic and DNA degradating mechanisms</p>
  
                <h6>Outreach Integration:</h6>
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<h6>Outreach Integration:</h6>
 
                  
 
                  
 
                 <p id="pp">We have extensive public engagement and education work in our Human Practices section, focusing early on how to best to influence the public in both lower and higher education on engaging with and understanding synthetic biology. But for the equality and diversity section of the Human Practices, we needed to created a well reasoned and grounded project, which both highlights the work of academics at the university and shapes more grounded opinions of equality and diversity in science. Consequently, we wanted to integrate each individual interview into the next, drawing from ideas from previous interviews, so we could properly discuss the problem of gender inequality and the issues raised by both academics and students. This is the best way to create a discussion between the academics as they are providing analysis and personal insight on the opinion and experiences of the academic before. It also allows us to discuss in depth, issues such as the problems associated with maternity and paternity leave in science or the need for massive social and structural change.</p>
 
                 <p id="pp">We have extensive public engagement and education work in our Human Practices section, focusing early on how to best to influence the public in both lower and higher education on engaging with and understanding synthetic biology. But for the equality and diversity section of the Human Practices, we needed to created a well reasoned and grounded project, which both highlights the work of academics at the university and shapes more grounded opinions of equality and diversity in science. Consequently, we wanted to integrate each individual interview into the next, drawing from ideas from previous interviews, so we could properly discuss the problem of gender inequality and the issues raised by both academics and students. This is the best way to create a discussion between the academics as they are providing analysis and personal insight on the opinion and experiences of the academic before. It also allows us to discuss in depth, issues such as the problems associated with maternity and paternity leave in science or the need for massive social and structural change.</p>

Revision as of 21:28, 13 October 2016