Difference between revisions of "Team:NCTU Formosa/Model"

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{{NCTU_Formosa}}
 
 
<html>
 
<html>
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<head>
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<meta charset="UTF-8">
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<script src="https://ajax.googleapis.com/ajax/libs/jquery/3.1.0/jquery.min.js"></script>
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<style>
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#modelingContainer {
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width::100%;
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margin-top: 63px;
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padding-top:30px;
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}
  
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#modelingTitle {
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font-size: 80px;
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text-align: center;
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color: #00b4ed;
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padding: 50px 30px 20px 30px;
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margin: 20px;
 +
letter-spacing: 4px;
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}
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#modelingContent {
 +
width: 100%;
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}
  
 +
.modelingPart {
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width: 80%;
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margin: 30px auto;
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}
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.modelingPartTitle {
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font-size: 25px;
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.modelingPartContentTitie {
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font-size: 22px;
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font-weight: normal;
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}
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.modelingPartContent {
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width: 90%;
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margin: 0 auto;
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}
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.modelingPartContent p {
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font-size: 18px;
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}
  
  
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#partB,#partC,#partD,#partE,#partF,#partG,#partH
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{display:none;
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}
  
  
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#titleA,#titleB,#titleC,#titleD,#titleE,#titleF,#titleG,#titleH
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{cursor:pointer;
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}
  
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<div class="column full_size">
 
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<h2> Modeling</h2>
 
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<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
 
  
  
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<h5> Inspiration </h5>
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</style>
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<p>
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</head>
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Here are a few examples from previous teams:
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<body>
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</p>
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<ul>
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<li><a href="https://2014.igem.org/Team:ETH_Zurich/modeling/overview">ETH Zurich 2014</a></li>
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<li><a href="https://2014.igem.org/Team:Waterloo/Math_Book">Waterloo 2014</a></li>
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</ul>
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<div id="modelingContainer">
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<h1 id="modelingTitle">Software—Toxin selection</h1>
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<div id="modelingContent">
 +
   
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    <!--modeling part-->
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    <!--1.-->
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    <div class="modelingPart">
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        <h2 class="modelingPartTitle" id="titleA" style="color:#02b2ec">I. Purpose</h2>
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        <div class="modelingPartContent" id="partA">
 +
            <p>To prove the concept of Pantide, we wanted to select three existing distinct spider toxin peptides with probable oral toxicity against the testee－Spodoptera litura(Tobacco cutworms). For the actual application of Pantide we, we needed some more knowledge base of peptides which have different molecular targets to promote Pantide applying to other orders of insects, and a different toxic mechanism to regularly alternate so as to avoid drug resistance.</p>
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            <p>To date, about 1500 toxin peptides from 97 spider species have been studied, though the number of spider toxin peptides is conservatively estimated up to 10 million. [1] So, our purpose is to establish a database collecting the information of those peptides, such as molecular target, taxon, toxicity, sequence. According to the database, if we first choose a target insect, then we can easily find out groups of suitable peptides used as Pantide. Therefore, we also need to create a method to select peptides from the database.</p>       
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        </div>
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    </div>
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 +
   
 +
        <!--2.-->
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    <div class="modelingPart">
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        <h2 class="modelingPartTitle" id="titleB" style="color:#19a0dc">II. Method</h2>
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        <div class="modelingPartContent" id="partB">
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        </div>     
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    </div>
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 +
   
 +
    <!--3.-->
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    <div class="modelingPart">
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        <h2 class="modelingPartTitle" id="titleC" style="color:#576fb1">III.Step 1: Crawler</h2>
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        <div class="modelingPartContent" id="partC">
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 +
        </div>
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    </div>
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 +
   
 +
    <!--4.-->
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    <div class="modelingPart" >
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        <h2 class="modelingPartTitle" id="titleD"  style="color:#7a546a">IV.Step 2: Filter</h2>
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        <div class="modelingPartContent" id="partD">
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        </div>   
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    </div>
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    <div class="modelingPart">
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        <h2 class="modelingPartTitle" id="titleE" style="color:#924189">V. Step 3: Selection</h2>
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        <div class="modelingPartContent" id="partE">
 +
           
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    </div>
 
</div>
 
</div>
  
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 +
    <div class="modelingPart">
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        <h2 class="modelingPartTitle" id="titleF" style="color:#9d3982">VI. Future</h2>
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        <div class="modelingPartContent" id="partF">
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        </div>
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    </div>
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<script>
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$(function(){
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$("#menuNav").children("li").eq(8).addClass("nav-active");
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$("#titleA").click(function(){
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$("#partB").slideUp(300);
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$("#partF").slideUp(300);
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$("#partA").slideToggle(300);
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$("html,body").animate({scrollTop:$("#titleA").offset().top-80},1000);
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$("#titleB").click(function(){
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$("#titleC").click(function(){
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setTimeout('$("html,body").animate({scrollTop:$("#titleC").offset().top-80},1000)',500);
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$("#titleD").click(function(){
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$("#partB").slideUp(300);
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$("#titleE").click(function(){
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</script>
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</body>
 
</html>
 
</html>

Revision as of 06:56, 15 October 2016

Software—Toxin selection

I. Purpose

To prove the concept of Pantide, we wanted to select three existing distinct spider toxin peptides with probable oral toxicity against the testee－Spodoptera litura(Tobacco cutworms). For the actual application of Pantide we, we needed some more knowledge base of peptides which have different molecular targets to promote Pantide applying to other orders of insects, and a different toxic mechanism to regularly alternate so as to avoid drug resistance.

To date, about 1500 toxin peptides from 97 spider species have been studied, though the number of spider toxin peptides is conservatively estimated up to 10 million. [1] So, our purpose is to establish a database collecting the information of those peptides, such as molecular target, taxon, toxicity, sequence. According to the database, if we first choose a target insect, then we can easily find out groups of suitable peptides used as Pantide. Therefore, we also need to create a method to select peptides from the database.

II. Method

III.Step 1: Crawler

IV.Step 2: Filter

V. Step 3: Selection

VI. Future