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== Our collaborations == | == Our collaborations == | ||
− | === | + | === Modeling for [https://2016.igem.org/Team:Toulouse_France Toulouse 2016] === |
+ | |||
+ | ====Introduction==== | ||
+ | We conceived a model in order to handle questions concerning the following situation: | ||
+ | A bacterial growth is carried out in a bioreactor, continually supplied in substrate. | ||
+ | Bacteria can possess 2 type of plasmids: | ||
+ | * plasmids 1 carry the toxin A gene and the anti-toxin B gene | ||
+ | * plasmids 2 carry the toxin B gene and the anti-toxin A gene | ||
+ | |||
+ | So during the growth each bacterium can have no plasmids, either one type of plasmids, or both types. | ||
+ | |||
+ | The aim of the model is to assess the evolution of plasmids throughout the culture, to determine which parameters can matter in the loss of those plasmids. As a plasmids can be a disadvantage for growth (energy spent into replicating processes) or a advantage (protection against a toxin) this question is hard to answer. But in this situation, where one type of plasmid can influence on the presence of the other tpye of plasmid in (and reciprocally) in the same bacteria, the question become too tough to answer and only a mathematical model can resolve such a interrogation. | ||
=== Data recovery [https://2016.igem.org/Team:Bordeaux Bordeaux 2016] === | === Data recovery [https://2016.igem.org/Team:Bordeaux Bordeaux 2016] === |