Difference between revisions of "Team:Dundee Schools"

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<h2> Welcome to iGEM 2016! </h2>
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<h2> Project Description </h2>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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<p>Every month running from February 2016 our team attended monthly meetings to discuss our project and brainstorm ideas, allowing us to talk about what we would like to work on throughout the summer. During these meetings we all came up with various ideas and eventually managed to narrow it down to the idea of targeting bacterial infections which cause diarrhoeal infections in the developing world.<br></br>
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Two of the main bacterial infections caught in developing countries are shigellosis and cholera. Shigellosis is an infection caused by the bacteria called Shigella. The bacteria can be passed from infected person’s faeces; this can be through contaminated water and food. When a person catches shigellosis they develop severe diarrhoea which can often contain blood.  165 million cases of Shigellosis are recorded each year, 163 million of them being in developing countries when hygiene levels are poor. This causes over 1 million deaths annually in third world countries.
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Cholera is a bacterial infection which causes diarrhoea, this can then lead to dehydration and often death. It can be caught by the transmission of the bacteria Vibrio cholera from an infected person’s faeces, this can occur when sanitation is very low so water and food can also become contaminated. An approximation of 3-5 million cases of Cholera are apparent each year, with over 100 000 deaths. <br></br>
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So we have decided to target Shigella and Vibrio cholera by using RNA interference. This will hopefully reduce the number of cases of people presenting with these bacterial infections. <br></br>
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Since beginning our summer project in June, the dry team have contacted various people and charities to get a range of opinions on our method of killing these bacterial infections. This helped lead our team in which direction is most effective for us to progress in, whilst the wet team have begun in the labs.
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We hope to design cheap and accessible bacteria that can be easily used and distributed to developing countries to kill bacterial infections, specifically cholera and shigellosis.</p>
  
 
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Revision as of 14:14, 1 July 2016

Project Description

Every month running from February 2016 our team attended monthly meetings to discuss our project and brainstorm ideas, allowing us to talk about what we would like to work on throughout the summer. During these meetings we all came up with various ideas and eventually managed to narrow it down to the idea of targeting bacterial infections which cause diarrhoeal infections in the developing world.

Two of the main bacterial infections caught in developing countries are shigellosis and cholera. Shigellosis is an infection caused by the bacteria called Shigella. The bacteria can be passed from infected person’s faeces; this can be through contaminated water and food. When a person catches shigellosis they develop severe diarrhoea which can often contain blood. 165 million cases of Shigellosis are recorded each year, 163 million of them being in developing countries when hygiene levels are poor. This causes over 1 million deaths annually in third world countries. Cholera is a bacterial infection which causes diarrhoea, this can then lead to dehydration and often death. It can be caught by the transmission of the bacteria Vibrio cholera from an infected person’s faeces, this can occur when sanitation is very low so water and food can also become contaminated. An approximation of 3-5 million cases of Cholera are apparent each year, with over 100 000 deaths.

So we have decided to target Shigella and Vibrio cholera by using RNA interference. This will hopefully reduce the number of cases of people presenting with these bacterial infections.

Since beginning our summer project in June, the dry team have contacted various people and charities to get a range of opinions on our method of killing these bacterial infections. This helped lead our team in which direction is most effective for us to progress in, whilst the wet team have begun in the labs. We hope to design cheap and accessible bacteria that can be easily used and distributed to developing countries to kill bacterial infections, specifically cholera and shigellosis.

Before you start:

Please read the following pages:

Styling your wiki

You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.

While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.

Wiki template information

We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!

Editing your wiki

On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!

Click here to edit this page!

Tips

This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:

  • State your accomplishments! Tell people what you have achieved from the start.
  • Be clear about what you are doing and how you plan to do this.
  • You have a global audience! Consider the different backgrounds that your users come from.
  • Make sure information is easy to find; nothing should be more than 3 clicks away.
  • Avoid using very small fonts and low contrast colors; information should be easy to read.
  • Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2016 calendar
  • Have lots of fun!
Inspiration

You can also view other team wikis for inspiration! Here are some examples:

Uploading pictures and files

You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to Team:YourOfficialTeamName/NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)

UPLOAD FILES