Difference between revisions of "Team:OUC-China"

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{{OUC-China}}
 
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<li><a href="https://2016.igem.org/Team:OUC-China/Design">Design</a></li>
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<li><a href="https://2016.igem.org/Team:OUC-China/Proof">Proof of concept </a></li>
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<li><a href="https://2016.igem.org/Team:OUC-China/Potential_application">Potential application</a></li>
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</ul>
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<li class="dropdown"><a class="dropdown-toggle" data-toggle="dropdown" href="#">Team<span class="caret"></span></a>
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<li><a href="https://2016.igem.org/Team:OUC-China/Team">Team</a></li>
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<li><a href="https://2016.igem.org/Team:OUC-China/Collaborations">Collaborations</a></li>
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<li><a href="https://2016.igem.org/Team:OUC-China/Protocol">Protocol</a></li>
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<li><a href="https://2016.igem.org/Team:OUC-China/Safety">Safety</a></li>
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<span class="sr{{OUC-China}}
 
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<img src="https://static.igem.org/mediawiki/2016/f/f7/T--OUC-China--index-right.png" style="margin-top:100%" alt="Slide Right">
 
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<div class="oucAbstract row">
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<div class="col-md-2">
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<h3 class="text-center">ABSTRACT</h3>
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<img src="https://static.igem.org/mediawiki/2016/d/d4/T--OUC-China--ab-icon2.png" class="img-responsive" alt="icon">
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                        <div class="clearfix"></div>
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<p>As is known, once forming stem-loops, the oligonucleotides will be more stable than the single-stranded ones. And mRNA with stem-loop at its 3’ or 5’ end often get a longer lifetime than the linear one owe to the stem-loop’s resistance to exonuclease. Our team tend to design a series of stem-loops each followed by the same endonuclease site and are transcribed as one polycistron. Once digested by endonuclease and seperate into several independent fragments, cistrons with different ∆G stem-loops will get different stability, thus influence the amount of expressed proteins. In this way, we can decouple the expression level of upstream and downstream genes of the same operon by simply designing different stem-loops. Futhermore, with quantitative ∆G of stem-loops, we even can achieve the ratio expression of target proteins. It is a creative regulating method and we attempt to provide a series of standard regulation parts for others.</p>
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<div class="oucMovie" style="background:url('https://static.igem.org/mediawiki/2016/9/99/T--OUC-China--movie-1.fw.png');width:100%;height:200px;">
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<a href="#"><img src="https://static.igem.org/mediawiki/2016/4/41/T--OUC-China--menu-icon-1.fw.png" class="img-responsive" alt="Purpose"><p class="text-center">Purpose</p></a>
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<div class="col-xs-4">
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<a href="#"><img src="https://static.igem.org/mediawiki/2016/1/1d/T--OUC-China--menu-icon-2.fw.png" class="img-responsive" alt="Principle"><p class="text-center">Principle</p></a>
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<a href="#"><img src="https://static.igem.org/mediawiki/2016/0/07/T--OUC-China--menu-icon-3.fw.png" class="img-responsive" alt="Potential"><p class="text-center">Potential</p></a>
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<a href="https://2016.igem.org/Team:OUC-China/Attributions"><img src="https://static.igem.org/mediawiki/2016/8/8a/T--OUC-China--menu-icon-4.fw.png" class="img-responsive" alt="Attrbution"><p class="text-center">Attrbutions</p></a>
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<a href="https://2016.igem.org/Team:OUC-China/Team"><img src="https://static.igem.org/mediawiki/2016/a/ad/T--OUC-China--menu-icon-5.fw.png" class="img-responsive" alt="Team"><p class="text-center">Team</p></a>
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<a href="https://2016.igem.org/Team:OUC-China/Human_Practices"><img src="https://static.igem.org/mediawiki/2016/0/04/T--OUC-China--menu-icon-6.fw.png" class="img-responsive" alt="Human Practices"><p class="text-center">Human Practices</p></a>
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<div class="oucBanner">
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        <h3 class="text-center">Cistrons Concerto</h3>
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<div class="row oucInformation">
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<h3>Thanks:</h3>
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<p><b>1.</b>Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences</p>
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<p><b>2.</b>NEW ENGLAND Biolabs</p>
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</div>
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<div class="col-md-5 Contact">
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<h3>Contact us:</h3>
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<p><b>E-mail</b>: oucigem@163.com</p>
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<p><b>Designed and built</b> by @ Jasmine Chen and @ Zexin Jiao</p>
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<p>We are OUC-iGEM
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<img src="https://static.igem.org/mediawiki/2016/5/58/T--OUC-China--foot4.png" width="70" height="70" alt="logo-one">
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Revision as of 07:59, 19 October 2016

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