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| − | <h1><B>Human Practice</B> </h1> | + | <h1><B>Integrating Human practices </br>into our project</B> </h1> |
| − | <h2><B>How we integrated Human Practices</br> into our project</B></h2> | + | <h2><B>How we integrated HP</B></h2> |
| | <div class="text1"><p></a> | | <div class="text1"><p></a> |
| − | The multidisciplinarity of our team has enabled us to take at heart the human practice aspect of our project. Indeed, all along the project, we did our best to complement scientific advances with Human practice activities. It was very interesting to see these activities and our knowledge getting more and more extensive and deepened as the science part of the project progressed. </br></br> | + | The unique expertise (i.e. <B>lawyers</B>, <B>designers</B>, <B>scientists</B>, <B>engineers</B>) of our team allowed us to take our project to another level; expanding on the discussions with professionals and truly incorporating human practice elements into all aspects of our project (i.e. <B>science</B>, <B>design</B>, and <B>application</B>). We were successful throughout the project, incorporating various sources of feedback and complementing the scientific advances with <B>human practice</B> activities. |
| | + | It was very interesting witnessing how this <B>iterative process</B> evolved as we discussed with professionals, scientists, and the public about our project. Our understanding and knowledge about synthetic biology deepened as the science portion of our project progressed. Thus, we had to take several important things into consideration to address various aspects of human practice. </br></br> |
| | + | </br></br> |
| | + | </p> |
| | + | </div> |
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| − | This aspect helped us take our project “outside the lab” and implement it as thoroughly as possible into the “real world”. Indeed, we conducted research to find out if there was a need for a mosquito trapping and analyzing system and quickly found out that yes, our system would be a great asset in the fight against emerging arboviruses. Then, in the making of the project, we worked closely with experts in the field (EID, CIBU, Anna-Bella Falloux…) in order to make sure our project best met the needs of the population, and finally, we took into account current ethical issues to build a system that would be in compliance with ethical standards (in particular by working with synenergene). </br></br>
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| − | We hope to see mos(kit)o live long and prosper! For this purpose, all along the project we documented our research and advance in a way that would make it possible for a future team (or someone else), to benefit from our research and build upon our project, in every aspect of our work (science, design and human practice). </br></br>
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| − | On the day we went to a middle school to organize a simulation of our project with the students. They were really interested in our project: they really invested their efforts in the project simulation, and they came up with great ideas for the design of our hardware part. In a broader way, the public who was introduced to our project was usually quite impressed of what we had achieved in so little time, and how such a multi-disciplinary could work so well together. So hopefully, our team can have served as an inspiring example to others! </br></br>
| + | <h2><B>In school, on the streets, and in science</B></h2> |
| | + | <div class="text1"><p></a> |
| | + | To begin, we took iGEM to the <B>schools</B>, the <B>streets</B>, and to the <B>science communities</B> to gain insight and understanding about people’s perspectives/opinions pertaining to the use of <B>synthetic biology</B>. We conducted <B>surveys</B>, gathering information from the public and had an <B>educational debate</B> in the schools. From these interactions, we incorporated aspects such as hardware design, the safety features of our device, and the fears of using synthetic biology into account as we designed our device to ensure it was as <B>safe</B> as possible. First, we destroyed our <B>GMO</B> in the lab and made sure it was not in our device. Second, having designers on our team allowed us to further our discussions with several <B>mosquito specialists</B> and build a device that met all of the criteria to ensure not just the safety of the <B>operators</B>, but also the <B>local public</B> that could potentially come in contact with the device. Additionally, our design was well thought out to include special features that attract the mosquitoes to the device, trap the mosquitoes inside the device, and safely absorb all potentially harmful liquids.</br></br> |
| | </p> | | </p> |
| | </div> | | </div> |
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| − | <h3><B> TIMELINE </br>Communication & Collaboration</B></br></h3> | + | <h2><B>With professionals & our design</B></h2> |
| − | | + | <div class="text1"><p></a> |
| − | | + | Next, we learned how <B>professionals</B>, that presently gather similar types of information about areas infested with mosquitoes, would receive our device and how there <B>current methods</B> could be easier if <B>Mos(kit)o</B> was applied in the field. Indeed, we conducted research to find out if there <B>was a need</B> for a mosquito trapping and analyzing system and quickly found out that yes, our system would be a great asset in the fight against emerging <B>arboviruses</B>. We understood what was currently being used and we imagined how our device could expand on methods that aren’t as efficient and make our device <B>more efficient</B>. This was crucial information that assisted us in the development of our <B>scenarios</B> as we took our project “outside the lab” and as thoroughly as possible, conceptually visualized Mos(kit)o in the <B>“real world”</B>. We were successful in doing this and received positive feedback from two professionals on potential <B>collaborations</B>, where they would like to use our device in a <B>pilot study</B>. Additionally, we had to think outside of the box and <B>anticipate</B> the social and ethical issues that could arise from developing a synthetic biology project. This was another successful discussion/collaboration with the <B>Rathenau Instituut</B> as we developed both scenarios, <B>integrating human practice</B> throughout the progression of our project.</br></br> |
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| − | <span class="day">25-26<sup>th</sup></span>
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| − | <span class="month">April</span>
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| − | <span class="year">2016</span>
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| − | <h2>Zika Summit 2016</h2>
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| − | <p>Zika Summit is a conference that aims to bring together scientists and public health professionals around the world working on Zika. We had the opportunity to present our project to professionals working on this arbovirus.
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| − | <span class="day">15<sup>th</sup></span>
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| − | <span class="month">May</span>
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| − | <span class="year">2016</span>
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| − | </span>
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| − | <h2>CIBU lab meeting</h2>
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| − | <p> <B>CIBU</B> is the Urgent Response to Biological Threats at the Institut Pasteur, supervised by <B>Jean-Claude Manuguerra</B>. We presented our project in front of all members of the CIBU lab and exchanged ideas about our method of detection, our global device, and the intellectual property protection offered at iGEM during the Q & A session that followed our talk.</p>
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| − | <span class="day">19<sup>th</sup></span>
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| − | <span class="month">May</span>
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| − | <span class="year">2016</span>
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| − | </span>
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| − | <h2>Young Researchers in Life Sciences</h2>
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| − | <p>The <B>YRLS</B> is a conference organized by young researchers (PhD, Post-docs, junior faculty) that features an interactive program which includes poster sessions, talks and round tables designed for other fellow young researchers. The wide variety of represented disciplines and topics allows attendees to deepen their knowledge of their own research field while broadening their horizons.</br></br> We had the opportunity to present our project at the conference as a Poster.</br></br> <img class="photo" src="https://static.igem.org/mediawiki/2016/1/1f/YRLS.png" width=70% alt="" /img></p>
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| − | <span class="day">20<sup>th</sup></span>
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| − | <span class="month">May</span>
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| − | <span class="year">2016</span>
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| − | <h2>introduction to labWORK</br> FOR middle school student </h2>
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| − | <p>The idea was to show in a very concrete way what are laboratory manipulations about. Thus bacterial culture and staining, plasmid DNA isolation, and protein crystals observation were conducted. The school Science, Technology and Maths teachers were also present. Gender equality in science observation and reporting was also also one of the points that was highlighted during the sessions.</br></br> <img class="photo" src="https://static.igem.org/mediawiki/2016/4/4f/Lab_at_school.jpg" width=70% alt="" /img></p>
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| − | <span class="date">
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| − | <span class="day">14<sup>th</sup></span>
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| − | <span class="month">June</span>
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| − | <span class="year">2016</span>
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| − | </span>
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| − | <h2>The game at the Germaine de Staël school</h2>
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| − | <p> The Mos(KIT)O system was simulated as a game with school students. In order to familiarize them to the growing problems relating to arboviruses, our team went to a middle school to simulate the scenario of our project through a game-like activity. They were asked to come up with a check-list of items to include in a trap, and also search for mosquitoes according to a prior explained affinity map (Forest, lakes, homes, wet areas etc).</br> </p>
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| − | <span class="date">
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| − | <span class="day">16<sup>th</sup></span>
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| − | <span class="month">June</span>
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| − | <span class="year">2016</span>
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| − | </span>
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| − | <h2>"jeu à débattre" with the association "arbre des connaissances"</h2>
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| − | <p>On Thursday June 16th, the iGEM Pasteur team went to attend a "Jeu à débattre" that was hosted by the association, "arbre des connaissances". This is a debate practice or round table where several synthetic biology processes are made available to a few villages, and the inhabitants have to decide for the pros and cons of acquiring them, considering environmental, economical, and health benefits. Our role was to advise the players during the game, and then to have a little debate about synthetic biology and the ethical and moral questions it raises. We also addressed the “legal” aspect as viewed from the point of view of French and US Law. </br></br><img class="photo" src="https://static.igem.org/mediawiki/2016/d/d2/Carte-de-lagglom%C3%A9ration.jpg" width=100% alt="" /img></p>
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| − | <span class="date">
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| − | <span class="day">28<sup>th</sup></span>
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| − | <span class="month">June</span>
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| − | <span class="year">2016</span>
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| − | </span>
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| − | <h2>Meeting with Anna-Bella Falloux</h2>
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| − | <p>We met <B>Anna-Bella Failloux</B> (entomologist, head of Arboviruses and Insect Vectors (AIV) research unit in the department of virology at Institut Pasteur) to have detailed information on mosquito ecology/habitat (types:aedes, culex) and behavior during feeding sorties(anthropophily, hematophagy).</p>
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| − | <span class="date">
| + | |
| − | <span class="day"></span>
| + | |
| − | <span class="month">July</br>Octo</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2> Ratheneau Institut</h2>
| + | |
| − | <p>The Ratheneau Institut is in cooperation with Synenergene, there aim is to foster an open dialogue on ethical research and innovation in synthetic biology. The Ratheneau Institut want to raising awareness of science and technology among public opinion and politicians. To do so they organize debates and conferences about science and technology.</br></br>
| + | |
| − | | + | |
| − | Since July, the Ratheneau Institut helped us to develop our project by guiding us on the steps for our scenarios. With their support and advice, we could develop an <B>Application Scenario</B> and <B>Technomoral Scenario.</B> ! </p>
| + | |
| − | </div>
| + | |
| − | </article>
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| − | | + | |
| − | <article>
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| − | <div class="inner">
| + | |
| − | <span class="date">
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| − | <span class="day">2-3<sup>th</sup></span>
| + | |
| − | <span class="month">July</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>The European experience</h2>
| + | |
| − | <p>We participated in the meet-up hosted by our friends from iGEM Ionis, and iGEM Evry. We had the opportunity to meet the European teams, and we took the opportunity to present them our project.</br></br> <img class="photo" src="https://static.igem.org/mediawiki/2016/1/1b/06.06_The_EE2.jpg" width=100% alt="" /img></p>
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| − | </div>
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| − | </article>
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| − | | + | |
| − | <article>
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| − | <div class="inner">
| + | |
| − | <span class="date">
| + | |
| − | <span class="day">6<sup>th</sup></span>
| + | |
| − | <span class="month">July</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Presentation at the ENSCI</h2>
| + | |
| − | <p>After a couple introductory lectures on research in design, biomaterials and synthetic biology, the Pasteur Paris iGEM 2016 team presented the Mos(kit)o project to the ENSCI-Les Ateliers school. This is one of the top design schools in the World (Red Dot Award 2015).</p>
| + | |
| − | </div>
| + | |
| − | </article>
| + | |
| − | | + | |
| − | <article>
| + | |
| − | <div class="inner">
| + | |
| − | <span class="date">
| + | |
| − | <span class="day">19<sup>th</sup></span>
| + | |
| − | <span class="month">July</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Meeting with Civic drone</h2>
| + | |
| − | <p>The meeting with <B>Civic drone</B> was intended to discuss with professionals to have more accurate information concerning the use of drones. This strategy concerns the part of the Mos(kit)o project related to remote access to areas with difficult terrain/climate levels. In particular we wanted to discuss data archiving, uploading, deposition-retrieval and analysis of Mos(kit)o traps anchorage to the UAVs.</p>
| + | |
| − | </div>
| + | |
| − | </article>
| + | |
| − | | + | |
| − | <article>
| + | |
| − | <div class="inner">
| + | |
| − | <span class="date">
| + | |
| − | <span class="day">22<sup>th</sup></span>
| + | |
| − | <span class="month">July</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Presentation about Intellectual property law </h2>
| + | |
| − | <p>The Paris Sud Jean Monnet university students Claudia, Victoire and Victor of Pasteur Paris iGEM made a presentation in front of the iGEM Team and Sandrine Daniel, head of the law of the Human resources Department of Institut Pasteur about Intellectual property law, the concept of Patents, and the aspect of iGEM Open science situation.
It was meant to toss around ideas to think about our project and its valorization in the future.</p>
| + | |
| − | </div>
| + | |
| − | </article>
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| − | | + | |
| − | | + | |
| − | | + | |
| − | <article>
| + | |
| − | <div class="inner">
| + | |
| − | <span class="date">
| + | |
| − | <span class="day">6<sup>th</sup></span>
| + | |
| − | <span class="month">Aug</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Meet-up Ile-de-France </h2>
| + | |
| − | <p>With help from two other Parisian teams, iGEM Paris Saclay and iGEM IONIS, we hosted the iGEM Ile-de-France MeetUp on August 6 at the Institut Pasteur. This event was the highlight of our summer. The attendees of the MeetUp were people from iGEM Paris Bettencourt, iGEM Evry, iGEM Ionis, iGEM UPMC (IMPACT), iGEM Aix-Marseille (one member), and iGEM Paris Saclay. We indeed had to abide to strong security requirements considering current state of Emergency in France. </br></br> <img class="photo" src="https://static.igem.org/mediawiki/2016/3/37/ILE_DE_FRANCE.jpg" width=100% alt="" /img></p>
| + | |
| − | </div>
| + | |
| − | </article>
| + | |
| − | | + | |
| − | <article>
| + | |
| − | <div class="inner">
| + | |
| − | <span class="date">
| + | |
| − | <span class="day">26<sup>th</sup></span>
| + | |
| − | <span class="month">Aug</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Meeting with EID </h2>
| + | |
| − | <p>Méditerranée (Entente Interdépartementale de Démoustication = Interdepartmental Mediterranean board for the control of mosquito). This organization is in charge of the fight against mosquito epidemics, which is recognized as a mission of public interest, for the Ministry of Health in France. Therefore EID is acting by delegation of authority, in a similar level as the Center for Disease Control (CDC) in the US.</br></br>
| + | |
| − | | + | |
| − | Our interview with <B>Gregory Lambert</B> (medical entomologist, coordinator of EID) has allowed us to have more information on mosquito behavior: </br>•Questions such as: How to lure them into the traps? </br>•What are the strategic areas to place our kit?</br> •How to optimize prevention? </br></br>All these details have allowed us to work in a more targeted way, so that our project is as efficient as possible, taking into account the mosquito lifestyle and optimizing safety for surrounding populations.
| + | |
| − | | + | |
| | </p> | | </p> |
| − | </div>
| + | </div> |
| − | </article>
| + | |
| | | | |
| − | <article> | + | <h2><B>Using law</B></h2> |
| − | <div class="inner"> | + | <div class="text1"><p></a> |
| − | <span class="date">
| + | And finally, during our project’s development, we realized that launching a <B>business</B> required a strong <B>intellectual property</B> strategy. We used the expertise of our team’s <B>law students</B> and presented at our <B>Ile de France meet-up</B> about open science and intellectual property law. From this presentation, we collected <B>feedback</B>, which revealed that not just our team had <B>questions</B> pertaining to the development of an intellectual property strategy that would be in compliance with the iGEM rules/framework, so did <B>other teams</B>. This was a missing piece to the puzzle that was essential for all teams to understand. Therefore, we decided to write <B>a repor</B>t evaluating the compatibility of an <B>open science model</B> with the pursuit of iGEM projects after the competition. It was our intent that it would be a document that would be <B>helpful</B> to other iGEM teams in the future. This document is available on our wiki (<a href="https://2016.igem.org/Team:Pasteur_Paris/Law"><u>evidence</u></a>). This topic was essential for our understanding. </br></br> |
| − | <span class="day">29<sup>th</sup></span>
| + | We hope to see Mos(kit)o live long and prosper! For this purpose, we <B>documented</B> our research in a way that would make it possible for <B>future teams</B>, or someone else, to <B>benefit</B> from our research and build upon our project! |
| − | <span class="month">Aug</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Presentation for AMGEN students</h2>
| + | |
| − | <p>The Amgen Scholars Program at Institut Pasteur provides twenty undergraduate students from European universities with the possibility to work under supervision on research projects during an eight-week summer internship at Institut Pasteur.</br></br>
| + | |
| | | | |
| − | Our presentation was to inform young researchers about Synthetic biology and its many uses, but also to present our project.
| + | </br></br> |
| | </p> | | </p> |
| − | </div>
| + | </div> |
| − | </article>
| + | |
| − | | + | |
| − | <article>
| + | |
| − | <div class="inner">
| + | |
| − | <span class="date">
| + | |
| − | <span class="day">15/16/17<sup>th</sup></span>
| + | |
| − | <span class="month">Sept</span>
| + | |
| − | <span class="year">2016</span>
| + | |
| − | </span>
| + | |
| − | <h2>Festival du vivant </h2>
| + | |
| − | <p>Whether it will be related to economy, health, agriculture or environment, different exhbits, talks and workshops brought together people from different horizons to meet and discuss, and display devices and concepts.</br></br>
| + | |
| − | We presented the 3D printed models of the Mos(kit)o kit, and a poster, alongside ENSCI-Les Ateliers our design student contingency of iGEM Pasteur Paris Team 2016. <img class="photo" src="https://static.igem.org/mediawiki/2016/f/f1/FESTIVAL_DU_VIVANT.jpg" width=100% alt="" /img></p>
| + | |
| − | </div>
| + | |
| − | </article>
| + | |
| − | | + | |
| − | | + | |
| − | | + | |
| − | </section>
| + | |
| − | | + | |
| | | | |
| − | <div class="text1"><p></a>For more information go to the sections: <a href="https://2016.igem.org/Team:Pasteur_Paris/Collaboration">Collaboration</a>, <a href="https://2016.igem.org/Team:Pasteur_Paris/Meet-up">Meetup</a>, <a href="https://2016.igem.org/Team:Pasteur_Paris/Engagement">Education and public "Engagement"</a>, and <a href="https://2016.igem.org/Team:Pasteur_Paris/Law">Law.</br></a></p></div>
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