Difference between revisions of "Team:Toulouse France"

 
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<p class="heading" style="text-align:center;">iGEM Toulouse Team presents<br><br><i>Paleotilis, a shield for the Lascaux cave</i></p>
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<h2>Back to the origins<br><br></h2>
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<font color="white"><p style="text-align:center; font-size:18px; vertical-align:middle;">iGEM Toulouse Team presents<br><i>Paleotilis, a shield for the Lascaux cave</i>
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<br><br> Back to the origins<br><br><p></font>
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<br><b style="font-size:18px;">What if iGEM stepped 18,000 years back? </b>
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<br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are monthly used and the cave is still in danger due to their limited efficiency. <br>
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<br><br>At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered <i>Bacillus subtilis</i> strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.
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<a href="https://2016.igem.org/Team:Toulouse_France/Context" class="part-little-projet">
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<div class="title-part-projet" style="text-align:center;">Project</div>
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<div style="text-align:justify; word-wrap: break-word;position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:80%; line-height:24px;">Discover the context of the <b>Paleotilis</b> project, and the three modules of its design: <b>Predation</b>, <b>Antifungals</b>, and <b>Confinement</b>. Click on the link to learn more about these constructions.<br><br></div>
<div style="border-bottom: 1px solid #fff; color:white; font-family:'Open Sans'; position:absolute; bottom:25px; right:22px; font-size:16px;">Read more</div>
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<div class="title-part-projet" style="color:white; ">Paleotilis</div>
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<a href="https://2016.igem.org/Team:Toulouse_France/Demonstrate" class="part-little-projet">
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<div  style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">To develop a predictive model</div>
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<div  style="text-align:justify;  word-wrap: break-word; position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:80%; line-height:24px">The different biobricks we constructed have been tested to measure their efficiency. There you will have an overview of the results.<br></div>
<div style="border-bottom: 1px solid #fff; color:white; font-family:'Open Sans'; position:absolute; bottom:28px; left:34px; font-size:16px;">Read more</div>
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<div  style="text-align:justify;  word-wrap: break-word; position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:80%; line-height:24px">Lot of projects and events have been done by the iGEM Toulouse team. We aimed <b>to explain synthetic biology, to debate about the use of GMOs and to transmit what we have learnt</b>.<br><br></div>
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To virtually visit the Lascaux cave !
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http://www.lascaux.culture.fr/#/fr/00.xml
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Latest revision as of 20:11, 19 October 2016

iGEM Toulouse 2016


iGEM Toulouse Team presents
Paleotilis, a shield for the Lascaux cave

Back to the origins


What if iGEM stepped 18,000 years back?

At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are monthly used and the cave is still in danger due to their limited efficiency.


At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered Bacillus subtilis strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.




Contacts