Difference between revisions of "Team:SYSU-MEDICINE/Collaborations"

 
(9 intermediate revisions by 2 users not shown)
Line 1: Line 1:
−
{{SYSU-MEDICINE}}
+
<html lang="en">
−
<html>
+
  
 +
<head>
 +
    <meta charset="UTF-8">
 +
    <link rel="icon" type="image/png" href="https://static.igem.org/mediawiki/2016/2/2a/T--SYSU-MEDICINE--logo_32%2A32.png" sizes="16x16">
 +
    <link rel="icon" type="image/png" href="https://static.igem.org/mediawiki/2016/2/2a/T--SYSU-MEDICINE--logo_32%2A32.png" sizes="32x32">
 +
    <!-- Latest compiled and minified CSS -->
 +
    <!--<link href='//cdn.webfont.youziku.com/webfonts/nomal/92549/46882/57f3d7e1f629d81a5077d03f.css' rel='stylesheet' type='text/css' />-->
 +
    <link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css" integrity="sha384-BVYiiSIFeK1dGmJRAkycuHAHRg32OmUcww7on3RYdg4Va+PmSTsz/K68vbdEjh4u" crossorigin="anonymous">
 +
    <!--jQuery-->
 +
    <script  src="https://code.jquery.com/jquery-3.1.1.min.js"  integrity="sha256-hVVnYaiADRTO2PzUGmuLJr8BLUSjGIZsDYGmIJLv2b8="  crossorigin="anonymous"></script>
 +
    <!-- Latest compiled and minified JavaScript -->
 +
    <script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/js/bootstrap.min.js" integrity="sha384-Tc5IQib027qvyjSMfHjOMaLkfuWVxZxUPnCJA7l2mCWNIpG9mGCD8wGNIcPD7Txa" crossorigin="anonymous"></script>
 +
    <style>
 +
        /*font*/
 +
        @font-face{font-family:"HelveticaNeueW02-45Ligh";src:url('//www.eyeem.com/css/fonts/88fcd49a-13c7-4d0c-86b1-ad1e258bd75d.eot?#iefix');src:url('//www.eyeem.com/css/fonts/88fcd49a-13c7-4d0c-86b1-ad1e258bd75d.eot?#iefix') format("eot"),url('//www.eyeem.com/css/fonts/9a2e4855-380f-477f-950e-d98e8db54eac.woff') format("woff"),url('//www.eyeem.com/css/fonts/fa82d0ee-4fbd-4cc9-bf9f-226ad1fcbae2.ttf') format("truetype"),url('//www.eyeem.com/css/fonts/48d599a6-92b5-4d43-a4ac-8959f6971853.svg#48d599a6-92b5-4d43-a4ac-8959f6971853') format("svg")}
 +
        *{
 +
            font-family:"HelveticaNeueW02-45Ligh","Arial",sans-serif;
 +
            letter-spacing: 0.4px;
 +
            line-height: 1.5em;
 +
        }
 +
        #HQ_page h1,#HQ_page h2,#HQ_page h3,#HQ_page h4,#HQ_page h5,#HQ_page p{
 +
            font-family:"HelveticaNeueW02-45Ligh","Arial",sans-serif;
 +
        }
 +
        #HQ_page p{
 +
            font-size: 20px;
 +
        }
 +
        #HQ_page td{
 +
            /*padding:0;*/
 +
            border:0;
 +
            vertical-align: top;
 +
        }
 +
        #HQ_page table {
 +
            border:0;
 +
        }
 +
        #HQ_page th{
 +
            border:0;
 +
            /*padding: 0;*/
 +
        }
 +
        /*override wiki*/
 +
        .menu_wrapper, #top_title, #sideMenu{display: none;}
 +
        #content {
 +
            width:100%;
 +
            padding:0;
 +
            margin: 16px auto;
 +
        }
 +
        #top_menu_under {
 +
            height: 0;
 +
        }
 +
        #top_menu_14 {
 +
            border-bottom: 0;
 +
        }
 +
        #globalWrapper {
 +
            font-size: 100%;
 +
            padding-bottom: 0;
 +
        }
 +
        #content {
 +
            margin-bottom: 0;
 +
        }
 +
        /*nav*/
 +
        .navbar {
 +
            border-radius: 0;
 +
            height: 50px;
 +
            margin-bottom:0;
 +
            z-index: 25;
 +
        }
 +
        .navbar-inverse .navbar-brand {
 +
            color: #fff;
 +
        }
 +
        .navbar-inverse .navbar-nav>.active>a, .navbar-inverse .navbar-nav>.active>a:focus, .navbar-inverse .navbar-nav>.active>a:hover {
 +
            background-color: rgba(0,0,0,0);
 +
            color: #999;
 +
            font-weight:600;
 +
        }
 +
        .navbar-inverse .navbar-nav>li>a {
 +
            color: #fff;
 +
            font-weight:600;
 +
        }
 +
        .navbar-inverse .navbar-nav>li>a:hover {
 +
            color: #999;
 +
            font-weight:600;
 +
        }
 +
        .navbar-nav>li{
 +
            top: -5px;
 +
        }
 +
        /*.mw-content-ltr ul, .mw-content-rtl .mw-content-ltr ul {*/
 +
        /*margin: 0 0.1;*/
 +
        /*}*/
 +
        .dropdown-menu>li>a {
 +
            font-weight: 600;
 +
        }
 +
        .third-level-list {
 +
            top: -10px;
 +
            left: 150px;
 +
        }
 +
        .jumbotron{
 +
            margin-bottom:0;
 +
            padding-top:10px;
 +
            padding-bottom:20px;
 +
        }
 +
        #jumbo-footer.jumbotron {
 +
            padding-top: 10px;
 +
            padding-bottom: 30px;
 +
            margin-bottom: 0;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container{
 +
            width: 1170px;
 +
            margin: 20px auto;
 +
            font-size: 18px;
 +
            color: #888;
 +
            /*font-weight: bold;*/
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .line{
 +
            height: 2px;
 +
            background-color: #bbb;
 +
            width: 100%;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact {
 +
            margin-top: 20px;
 +
            margin-left: 10px;
 +
            height: 140px;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .title{
 +
            font-weight: bold;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact ul{
 +
            list-style: none;
 +
            padding-left: 0;
 +
            margin-left: 0;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact ul.float-contact {
 +
            float:left;
 +
            width: 400px;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact ul li {
 +
            margin-top: 5px;
 +
            margin-bottom: 5px;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact ul li a img{
 +
            width: 30px;
 +
            height: 30px;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact ul li a {
 +
            color: #888;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact ul li a:hover, #jumbo-footer.jumbotron>.footer-container .contact ul li a:active, #jumbo-footer.jumbotron>.footer-container .contact ul li a:focus {
 +
            color: #888;
 +
            text-decoration: none;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .contact .float-contact-right {
 +
            float:right;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .copyright{
 +
            margin-top: 5px;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .copyright .text {
 +
            font-size: 16px;
 +
            float: left;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .copyright .icon{
 +
            float: right;
 +
        }
 +
        #jumbo-footer.jumbotron>.footer-container .copyright .icon img {
 +
            width: 25px;
 +
            height: 25px;
 +
        }
 +
        #wechatModal .modal-dialog{
 +
            width: 332px;
 +
            margin-top: 100px;
 +
            z-index: 2000;
 +
        }
 +
        /*content*/
 +
        .jumbotron .my-content{
 +
            margin: 0 auto;
 +
            width: 960px;
 +
        }
 +
        .jumbotron .my-content h2 {
 +
            text-align: center;
 +
            font-weight: bolder;
 +
            font-size: 40px;
 +
            margin-bottom:30px;
 +
        }
 +
        .jumbotron .my-content p {
 +
            line-height: 1.5em;
 +
            font-size: 20px;
 +
            color: #333;
 +
        }
 +
        .jumbotron#safety-head {
 +
            padding-bottom: 0;
 +
        }
 +
        /*table*/
 +
        table tr td.left{
 +
            width: 250px;
 +
            vertical-align: text-top;
 +
        }
 +
        table tr td.center{
 +
            width: 1px;
 +
            background-color: rgba(0,0,0,0.8);
 +
        }
 +
        table tr td.padding{
 +
            width: 20px;
 +
        }
 +
        table tr td.left>h1{
 +
            text-align: left;
 +
            font-size: 28px;
 +
            font-weight: bolder;
 +
            vertical-align: text-top;
 +
            margin-top: -10px;
 +
            color: #333;
 +
        }
 +
        table tr td.left>h3{
 +
            text-align: left;
 +
            font-size: 28px;
 +
            font-weight: bolder;
 +
            vertical-align: text-top;
 +
            margin-top:0;
 +
            color: #333;
 +
        }
 +
        table tr td.right{
 +
            width: 689px;
 +
            margin-left: 20px;
 +
            vertical-align: text-top;
 +
            font-size: 18px;
 +
            color: #333;
 +
        }
 +
        table tr.blank{
 +
            height: 30px;
 +
        }
 +
        /*content*/
 +
        .jumbotron .my-content{
 +
            margin: 0 auto;
 +
            width: 960px;
 +
        }
 +
        .jumbotron .my-content h2 {
 +
            text-align: center;
 +
            font-weight: bolder;
 +
            font-size: 40px;
 +
            margin-bottom:30px;
 +
        }
 +
        .jumbotron .my-content p {
 +
            line-height: 1.5em;
 +
            font-size: 20px;
 +
            color: #333;
 +
        }
 +
        .jumbotron#content{
 +
            background-color: #fff;
 +
        }
 +
        .jumbotron#content p a{
 +
            color: #333;
 +
        }
 +
        .jumbotron#content img{
 +
            width: 90%;
 +
            margin: 10px auto;
 +
            display: block;
 +
        }
 +
        .jumbotron#content span.note{
 +
            width: 80%;
 +
            font-size: 16px;
 +
            color: #999;
 +
            margin: 0 auto;
 +
            display: block;
 +
        }
 +
        .jumbotron#table-content {
 +
            background-color: #fff;
 +
        }
 +
        .table-striped thead tr{
 +
            background-color: #f2f2f2;
 +
        }
  
 +
    </style>
 +
    <style>
 +
        /*backtoTop*/
 +
        .backtoTop{
 +
            height: 50px;
 +
            width: 50px;
 +
            position: absolute; //绝对定位
 +
            padding-top: 8px;
 +
            right: 10px;
 +
            z-index: 9999;
 +
            /*避免闪烁*/
 +
            -moz-transition: all 1s ease;
 +
            -webkit-transition: all 1s ease;
 +
            -o-transition: all 1s ease;
 +
            transition: all 1s ease;
 +
            /*避免闪烁*/
 +
            /*background: blue;*/
 +
            cursor: pointer;
 +
            text-align: center;
 +
        }
 +
    </style>
 +
    <script type="text/javascript">
 +
        $(document).ready(function() {
 +
//          wechat qr code
 +
            var canHide= true;
 +
            $('#wechatModal').on('show.bs.modal', function (e) {
 +
                // do something...
 +
                $("#wechatModal").after('<div class="modal-backdrop fade in"></div>');
 +
            });
 +
            $(".modal").click(function() {
 +
//                console.log("click");
 +
                //$(this).remove();
 +
                if (canHide) {
 +
                    $(".modal-backdrop").remove();
 +
                    $('#wechatModal').modal('hide');
 +
                }
 +
            });
 +
            $(".modal-dialog").click(function() {
 +
                canHide = false;
 +
            });
 +
            $(".modal").mousemove(function() {
 +
                canHide = true;
 +
            });
 +
            $(".third-level-list").css("left", "120px");
 +
//          third level menu on nav
 +
            $(".third-level-menu").mouseenter(function() {
 +
                console.log("mouse in");
 +
                $(this).addClass("open");
  
 +
            });
 +
            $(".third-level-menu").mouseleave(function() {
 +
                console.log("mouse in");
 +
                $(this).removeClass("open");
 +
            });
 +
            $(".dropdown").mouseenter(function() {
 +
                $(this).addClass("open");
 +
            });
 +
            $(".dropdown").mouseleave(function() {
 +
                $(this).removeClass("open");
 +
            });
  
 +
//            backtotop
 +
            $(window).scroll( function() {              //滚动时触发
 +
                var top = $(document).scrollTop(),      //获取滚动条到顶部的垂直高度
 +
                        height = $(window).height();
 +
//                      height = 600;
 +
                console.log(height+" "+top);//获得可视浏览器的高度
 +
                if(top > 100){
 +
                    $("#backToTop").show(200, function(){
 +
                        $("#backToTop").css({
 +
                            top: height + top - 80
 +
                        })
 +
                    });
 +
                }
 +
            });
 +
            /*点击回到顶部*/
 +
            $('#backToTop').click(function(){
 +
                $('html, body').animate({
 +
                    scrollTop: 0
 +
                }, 500);
 +
            });
 +
        });
 +
    </script>
 +
</head>
  
−
<div class="column full_size">
+
<body>
  
 +
<nav class="navbar navbar-inverse">
 +
    <div class="container-fluid">
 +
        <!-- Brand and toggle get grouped for better mobile display -->
 +
        <div class="navbar-header">
 +
            <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#bs-example-navbar-collapse-1" aria-expanded="false">
 +
                <span class="sr-only">Toggle navigation</span>
 +
                <span class="icon-bar"></span>
 +
                <span class="icon-bar"></span>
 +
                <span class="icon-bar"></span>
 +
            </button>
 +
            <a class="navbar-brand" href="https://2016.igem.org/Team:SYSU-MEDICINE">
 +
                <img style="height: 40px; width: 40px; margin-top: -10px " src="https://2016.igem.org/wiki/skins/Igem/images/IGEM_white_letters.png">
 +
            </a>
 +
            <a class="navbar-brand" href="https://2016.igem.org/Team:SYSU-MEDICINE">SYSU-MEDICINE</a>
 +
        </div>
  
−
<p>
+
        <!-- Collect the nav links, forms, and other content for toggling -->
−
Sharing and collaboration are core values of iGEM. We encourage you to reach out and work with other teams on difficult problems that you can more easily solve together.
+
        <div class="collapse navbar-collapse" id="bs-example-navbar-collapse-1">
−
</p>
+
            <ul class="nav navbar-nav navbar-right">
 +
                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE">HOME</a></li>
 +
                <li class="dropdown">
 +
                    <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">PROJECT<span class="caret"></span></a>
 +
                    <ul class="dropdown-menu">
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Description">Description</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Results">Results</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Protocol">Protocol</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Notebook">Notebook</a></li>
 +
                        <li class="dropdown third-level-menu">
 +
                            <a href="#" class="dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">For Judgement <span class="glyphicon glyphicon-chevron-right"></span></a>
 +
                            <ul class="third-level-list dropdown-menu">
 +
                                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Proof">Proof of Concept</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Demonstrate">Demonstrate</a></li>
 +
                            </ul>
 +
                        </li>
 +
                    </ul>
 +
                </li>
 +
                <li class="dropdown">
 +
                    <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">HUMAN PRACTICES<span class="caret"></span></a>
 +
                    <ul class="dropdown-menu">
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Our_Story">Our Story</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Interview">Interview</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Ethics">Ethics</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Legislation">Legislation</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Products">Products</a></li>
 +
                        <li class="dropdown third-level-menu">
 +
                            <a href="#" class="dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">For Judgement <span class="glyphicon glyphicon-chevron-right"></span></a>
 +
                            <ul class="third-level-list dropdown-menu">
 +
                                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/HP/Silver">Silver</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/HP/Gold">Gold</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Integrated_Practices">Integrated Practices</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Engagement">Engagement</a></li>
 +
                            </ul>
 +
                        </li>
 +
                    </ul>
 +
                </li>
 +
                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Modeling">MODELING</a></li>
 +
                <li class="dropdown active">
 +
                    <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">TEAM<span class="caret"></span></a>
 +
                    <ul class="dropdown-menu">
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Team">Team</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Attributions">Attributions</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Collaborations">Collaborations</a></li>
 +
                    </ul>
 +
                </li>
 +
 
 +
                <li class="dropdown">
 +
                    <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">PARTS<span class="caret"></span></a>
 +
                    <ul class="dropdown-menu">
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Parts">Parts</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Basic_Part">Basic Parts</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Composite_Part">Composite Parts</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Part_Collection">Part Collection</a></li>
 +
                    </ul>
 +
                </li>
 +
                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Safety">SAFETY</a></li>
 +
                <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Judging">JUDGING</a></li>
 +
            </ul>
 +
        </div><!-- /.navbar-collapse -->
 +
    </div><!-- /.container-fluid -->
 +
 
 +
</nav>
 +
 
 +
 
 +
 
 +
<div class="jumbotron" id="safety-head">
 +
    <div class="my-content">
 +
        <table>
 +
            <tr>
 +
                <td class="left">
 +
                    <h1>Collaboration</h1>
 +
                </td>
 +
                <td class="padding"></td>
 +
                <td class="right">
 +
                    As a hallmark of iGEM, collaboration has been an important part to strengthen contacts and promote friendships with other teams. In 2016 iGEM, we, SYSU-MEDICINE, communicated with several teams and gained a lot.
 +
                    <br/>
 +
                    <br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#1" name="1">ShanghaiTechChina_B</a><br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#2" name="2">AHUT_China and NAU-China</a><br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#3" name="3">Newsletter held by XMU-China</a><br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#4" name="4">NEU-China</a><br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#5" name="5">TMMU_China</a><br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#6" name="6">CCiC</a><br/>
 +
                    <span class="glyphicon glyphicon-stop"></span> <a href="#7" name="7">SYSU_China</a><br/>
 +
                    <br/>
 +
                </td>
 +
            </tr>
 +
        </table>
 +
    </div>
 
</div>
 
</div>
  
−
<div class="column half_size">
 
  
−
<h4> Which other teams can we work with? </h4>
 
−
<p>
 
−
You can work with any other team in the competition, including software, hardware, high school and other tracks. You can also work with non-iGEM research groups, but they do not count towards the iGEM team collaboration silver medal criterion.
 
−
</p>
 
  
−
<p>
+
<div class="jumbotron" id="content">
−
In order to meet the silver medal criteria on helping another team, you must complete this page and detail the nature of your collaboration with another iGEM team.
+
    <div class="my-content">
−
</p>
+
        <p>
 +
        </p>
  
 +
        <br/>
 +
        <h2 id="1">Collaboration with Team ShanghaiTechChina_B</h2>
 +
 +
        <p>
 +
            <br/>
 +
            · Team ShanghaiTechChina_B aimed to confirm the therapeutic effect of the over-expression epidermal growth factor (EGF) on E.coli in colitis microenvironment and hoped to utilize the peptide EGF secreted by the engineered bacteria to repair the colon tissue in patients.<br/>
 +
            · Our team established the inflammatory bowel disease (IBD) model to confirm the homing capability of the modified bone marrow derived mesenchymal stem cells (MSCs). <br/>
 +
            As a result, we assisted Team ShanghaiTechChina_B with animal model establishment to confirm the function of EGF derived from modified E.coli to prove the effect of the peptide in vivo. <br/>
 +
            <br/>
 +
            <b><big>Experiment Design</big></b><br/>
 +
            During the competition, we received the purified EGF peptide expressed by the engineered bacteria from Team ShanghaiTechChina_B. We established the IBD mice model and injected the EGF solution into the colon by cocolysis.<br/>
 +
            We referred to the related article to select the effective way (TNBS) to establish the model and examine the effect of EGF.<sup>[1][2]</sup>After IBD mice model establishment,<br/>
 +
            1. Selected several similar mice and weighed them on the second day of fasting.<br/>
 +
            2. Chose half of them for EGF solution enema as an experiment group, and the rest of them were dealt with normal saline as the control group.<br/>
 +
            3. Weighed each of them at the same time every day.<br/>
 +
            4. After the fifth day, sacrificed the mice by cervical dislocation and measured the length of colons.<br/>
 +
            <br/>
 +
            <b><big>Experiment Results</big></b><br/>
 +
 +
        </p>
 +
 +
        <table class="table table-hover table-striped" style="color:#666;font-size:14px">
 +
            <caption style="text-align:center">Table of Mice Weight</caption>
 +
            <thead>
 +
            <tr>
 +
                <th>Sample</th>
 +
                <th>Day 1</th>
 +
                <th>Day 2</th>
 +
                <th>Day 3</th>
 +
                <th>Day 4</th>
 +
                <th>Day 5</th>
 +
            </tr>
 +
            </thead>
 +
 +
            <tfoot>
 +
            <tr>
 +
                <td style="text-align:center; " colspan="6">Unit:Gram</th>
 +
            </tr>
 +
            <tr>
 +
            </tfoot>
 +
 +
            <tbody>
 +
            <tr>
 +
                <td>1</td>
 +
                <td>20.45</td>
 +
                <td>19.64</td>
 +
                <td>18.89</td>
 +
                <td>17.63</td>
 +
                <td>17.66</td>
 +
            </tr>
 +
 +
            <tr>
 +
                <td>1</td>
 +
                <td>20.45</td>
 +
                <td>19.64</td>
 +
                <td>18.89</td>
 +
                <td>17.63</td>
 +
                <td>17.66</td>
 +
            </tr>
 +
 +
            <tr>
 +
                <td>2</td>
 +
                <td>19.55</td>
 +
                <td>18.31</td>
 +
                <td>18.08</td>
 +
                <td>17.98</td>
 +
                <td>18.03</td>
 +
            </tr>
 +
 +
            <tr>
 +
                <td>3</td>
 +
                <td>22.53</td>
 +
                <td>22.01</td>
 +
                <td>22.10</td>
 +
                <td>22.49</td>
 +
                <td>22.17</td>
 +
            </tr>
 +
 +
            <tr>
 +
                <td>4</td>
 +
                <td>23.46</td>
 +
                <td>22.98</td>
 +
                <td>22.88</td>
 +
                <td>23.36</td>
 +
                <td>23.98</td>
 +
            </tr>
 +
            </tbody>
 +
        </table>
 +
 +
        <p>
 +
            <span class="note" style="text-align: center">
 +
                Figure 7.1
 +
            </span>
 +
            <br/>
 +
        </p>
 +
        <table>
 +
            <tr>
 +
                <td style="text-align: center; width:450px">
 +
                    <img src="https://static.igem.org/mediawiki/2016/2/2e/T--SYSU-MEDICINE--collaboration-7.2.png">
 +
                </td>
 +
                <td style="text-align: center; width:450px">
 +
                    <img src="https://static.igem.org/mediawiki/2016/1/13/T--SYSU-MEDICINE--collaboration-7.3.png">
 +
                </td>
 +
            </tr>
 +
            <tr>
 +
                <td style="text-align: center">
 +
                    <span class="note" style="text-align: center;">
 +
                        Figure 7.2
 +
                    </span>
 +
                </td>
 +
                <td style="text-align: center">
 +
                    <span class="note" style="text-align: center;">
 +
                        Figure 7.3
 +
                    </span>
 +
                </td>
 +
            </tr>
 +
        </table>
 +
 +
        <p>
 +
            After injecting EGF solution into the colon by coloclysis, we were excited to see that the colon length and the weight loss improved a lot comparing with the IBD mice without injection, which indicated that EGF derived from modified E.coli had repair effect on the damaged colon in IBD model.<br/>
 +
            <br/>
 +
            Reference:
 +
            <a href="https://2016.igem.org/Team:ShanghaiTechChina_B/Collaborations#SYSU_MEDICINE" target="_blank">https://2016.igem.org/Team:ShanghaiTechChina_B/Collaborations#SYSU_MEDICINE</a><br/>
 +
        </p>
 +
        <br/>
 +
 +
        <h2 id="2" style="font-size: 30px">Conference with Team AHUT_China and NAU-China</h2>
 +
        <p>
 +
            <br/>
 +
            On 28th, September, 2016, we were invited and held a conference on iGEM projects with Team AHUT_China and NAU-China. It was a great opportunity for us to publicize our team and projects in other cities. On this conference, we introduced great therapeutic effects of our engineered MSCs on inflammatory diseases and shared different opinions on cell therapy. We were excited to find that most audience were interested in this new chassis (MSCs) including its phenotype, function and low immunogenicity. After that, they raised questions on our biosafety of our engineered MSCs and gave some suggestion to us. We were pleased to communicate with people from different fields.<br/>
 +
            <br/>
 +
 +
            <img src="https://static.igem.org/mediawiki/2016/8/82/T--SYSU-MEDICINE--collaboration-7.4.png">
 +
            <span class="note" style="text-align: center">
 +
                Figure 7.4
 +
            </span>
 +
            <br/>
 +
        </p>
 +
        <h2 id="3">Participation in Newsletter held by XMU-China</h2>
 +
        <p>
 +
            <br/>
 +
            Since it was the first time for our team, SYSU-MEDICINE, to participate in iGEM competition, we were eager to publicize us as well as our projects. Learning that Newsletter is a great stage for iGEMers to communicate and collaborate with each other, we showed ourselves by publishing our ideas, questionnaire, photos and so on. Surprisingly, we received some replies and suggestions.<br/>
 +
            <br/>
 +
            <img src="https://static.igem.org/mediawiki/2016/b/ba/T--SYSU-MEDICINE--collaboration-7.5.png">
 +
            <span class="note" style="text-align: center">
 +
                Figure 7.5
 +
            </span>
 +
            <br/>
 +
        </p>
 +
        <h2 id="4">Meet-up with Team NEU-China</h2>
 +
        <p>
 +
            <br/>
 +
            It’s important to find new friends in iGEM. On 20th, August, the team leader of NEU-China happened to come to Guangzhou, China for a summer camp. We met him and bring him to sight-seeing around. Referring to collaboration, he mentioned that their team might need modelling help at later phase of the project. We discussed about assistance and drew a conclusion that if time and energy permit, we will help them with modelling.<br/>
 +
            <br/>
 +
            <img src="https://static.igem.org/mediawiki/2016/3/38/T--SYSU-MEDICINE--collaboration-7.6.png">
 +
            <span class="note" style="text-align: center">
 +
                Figure 7.6
 +
            </span>
 +
            <br/>
 +
            In September, we had cooperation with them. Since our experiments had a lot of things in common, we cooperated in various aspects of the whole project. Especially, we had a deep discussion of the concept of modelling and exchanged views about the details, such as the way to predict the density of factors in the mice. At first, they were interested in our parts’confirmation in animal models, like fitting of fluorescence intensity. Later, they wanted to introduce that in their own models. We also gave them a little instruction about how to predict the factors in mice and analysis the data.<br/>
 +
            <br/>
 +
        </p>
 +
        <h2 id="5">Communication with Team TMMU_China</h2>
 +
        <p>
 +
            <br/>
 +
            At the very beginning, we talked about the Neutral Network with regards to its usage as classification, and regression model. We were excited to find out that both of our teams took similar ways to predict values. When realizing that there was a problem about how to define parameters, we both found a method to solve it. It was so happy to get the chance to communicate with someone who owned passion towards data analysis and we even promised to meet in Boston and attended some biostatistics classes in Harward.<br/>
 +
            <br/>
 +
        </p>
 +
        <h2 id="6">Participation in CCiC<br/>(Conference of China iGEMer Committee, 2016)</h2>
 +
        <p>
 +
            <br/>
 +
            This year, Conference of China iGEMer Committee, 2016 is successfully held by School of Life Sciences, Sun Yat-sen University. (2nd~4th, September)<br/>
 +
            After invited, our team presented a poster and share our story in SYSU-CCiC conference. As a medical team, we brought a new therapeutical tool, mesenchymal stem cells, to participants, who were mostly not familiar with them. Surprisingly, we were excited that our project, MSCavalry: MSCs of next generation, attracted many attenders, which arose utmost praise and encouragement to us all.<br/>
 +
            SYSU-CCiC conference also provided us with an opportunity to communicate with other teams. During the conference, we found both advantages and disadvantages in our project and acquire significant suggestions, such as biosafety, ethics, efficiency of parts, etc. when we communicated with others. In next 2 months, we tried to solve them and change into better. We sincerely hoped conference next year can attract more teams and be more influential.<br/>
 +
            <br/>
 +
            <img src="https://static.igem.org/mediawiki/2016/1/11/T--SYSU-MEDICINE--collaboration-7.7.png">
 +
            <span class="note" style="text-align: center">
 +
                Figure 7.7
 +
            </span>
 +
            <br/>
 +
        </p>
 +
 +
        <h2 id="7">Collaboration with SYSU_China</h2>
 +
        <p>
 +
            <br/>
 +
            As a new team for iGEM competition, we had confronted various problems since we established our team. Consequently, we asked SYSU-China, SYSU’s first iGEM team, for help, such as details of registration and how to understand judging criteria. As for part submission, they provided us backbone plasmid, pSB1C3. In addition, we gave them reagent for Interlab. We were pleased to learn from each other.<br/>
 +
            <br/>
 +
            <img src="https://static.igem.org/mediawiki/2016/a/ac/T--SYSU-MEDICINE--collaboration-7.8.png">
 +
            <span class="note" style="text-align: center">
 +
                Figure 7.8
 +
            </span>
 +
            <br/>
 +
            Reference can be seen in <a href="https://2016.igem.org/Team:SYSU-CHINA/HumanPractice/Collaboration" target="_blank" >https://2016.igem.org/Team:SYSU-CHINA/HumanPractice/Collaboration</a><br/>
 +
            <br/>
 +
 +
            <br/>
 +
            <b><big>Reference:</big></b><br/>
 +
            [1] Wirtz S, Neufert C, Weigmann B, et al. Chemically induced mouse models of intestinal inflammation [J]. Nature protocols, 2007, 2(3): 541-546.<br/>
 +
            [2] Chen Q Q, Yan L, Wang C Z, et al. Mesenchymal stem cells alleviate TNBS-induced colitis by modulating inflammatory and autoimmune responses[J]. World J Gastroenterol, 2013, 19(29): 4702-4717.<br/>
 +
        </p>
 +
 +
    </div>
 
</div>
 
</div>
  
 +
<!--backToTop-->
 +
<div id="backToTop" class="backtoTop">
 +
    <img width="100%" src="https://static.igem.org/mediawiki/2016/3/30/T--SYSU-MEDICINE--scrollup.png">
 +
</div>
  
 +
<!--footer-->
 +
<div class="jumbotron" id="jumbo-footer">
 +
    <div class="footer-container">
 +
        <div class="title">
 +
            Contact us
 +
        </div>
 +
        <div class="line"></div>
 +
        <div class="contact">
 +
            <ul class="float-contact">
 +
                <li>
 +
                    <a href="http://weibo.com/u/5999650333">
 +
                        <img style="height: 32px; width: 32px" src="https://static.igem.org/mediawiki/2016/0/06/T--SYSU-MEDICINE--weibo.png">
 +
                        iGEMxSYSU-MEDICINE
 +
                    </a>
 +
                </li>
 +
                <li>
 +
                    <a href="https://www.facebook.com/IGEM-SYSU-Medicine">
 +
                        <img style="height: 27px; width: 27px; margin-left: 2px;margin-right:2px;" src="https://static.igem.org/mediawiki/2016/a/a1/T--SYSU-MEDICINE--facebook.png">
 +
                        IGEM SYSU-Medicine
 +
                    </a>
 +
                </li>
 +
                <li>
 +
                    <a href="#">
 +
                        <img src="https://static.igem.org/mediawiki/2016/4/43/T--SYSU-MEDICINE--email.png">
 +
                        SYSU_MEDICINE@163.com
 +
                    </a>
 +
                </li>
 +
            </ul>
 +
            <ul class="float-contact">
 +
                <li>
 +
                    <a href="#" data-toggle="modal" data-target="#wechatModal">
 +
                        <img src="https://static.igem.org/mediawiki/2016/6/6e/T--SYSU-MEDICINE--wechat.png">
 +
                        SYSU-MEDICINE
 +
                    </a>
 +
                </li>
 +
                <li>
 +
                    <a href="https://twitter.com/IgemSysu">
 +
                        <img src="https://static.igem.org/mediawiki/2016/1/1c/T--SYSU-MEDICINE--twitter.png">
 +
                        iGEM SYSU-MEDICINE
 +
                    </a>
 +
                </li>
  
−
<div class="column half_size">
+
            </ul>
−
<p>
+
            <div class="float-contact-right">
−
Here are some suggestions for projects you could work on with other teams:
+
                <img style="width: 140px" src="https://static.igem.org/mediawiki/2016/5/5e/T--SYSU-MEDICINE--Igemlogo_banner.png">
−
</p>
+
                <img style="height: 100px" src="https://static.igem.org/mediawiki/2016/d/df/T--SYSU-MEDICINE--SYSU-MEDICINE.png">
 +
            </div>
 +
        </div>
 +
        <div class="line"></div>
 +
        <div class="copyright">
 +
            <div class="text">
 +
                &copy; 2016 SYSU-MEDICINE. All Rights Reserved.
 +
            </div>
 +
            <div class="icon" >
 +
                <img src="https://static.igem.org/mediawiki/2016/f/f5/T--SYSU-MEDICINE--china_2x.png">
 +
                <img src="https://static.igem.org/mediawiki/2016/a/a9/T--SYSU-MEDICINE--SYSU.png">
 +
            </div>
 +
        </div>
 +
    </div>
  
−
<ul>
 
−
<li> Improve the function of another team's BioBrick Part or Device</li>
 
−
<li> Characterize another team's part </li>
 
−
<li> Debug a construct </li>
 
−
<li> Model or simulating another team's system </li>
 
−
<li> Test another team's software</li>
 
−
<li> Help build and test another team's hardware project</li>
 
−
<li> Mentor a high-school team</li>
 
−
</ul>
 
 
</div>
 
</div>
  
 +
<!-- Wechat QRCode Modal -->
 +
<div class="modal fade" id="wechatModal" tabindex="-1" role="dialog" aria-labelledby="myModalLabel" data-backdrop="false">
 +
    <div class="modal-dialog" role="document">
 +
        <div class="modal-content">
 +
 +
            <div class="modal-body">
 +
                <img style="height: 300px;width: 300px;" src="https://static.igem.org/mediawiki/2016/0/07/T--SYSU-MEDICINE--wechat-qrcode.png">
 +
            </div>
 +
 +
        </div>
 +
    </div>
 +
</div>
  
 +
</body>
 
</html>
 
</html>

Latest revision as of 21:12, 19 October 2016

Collaboration

 As a hallmark of iGEM, collaboration has been an important part to strengthen contacts and promote friendships with other teams. In 2016 iGEM, we, SYSU-MEDICINE, communicated with several teams and gained a lot.

ShanghaiTechChina_B
AHUT_China and NAU-China
Newsletter held by XMU-China
NEU-China
TMMU_China
CCiC
SYSU_China


Collaboration with Team ShanghaiTechChina_B


· Team ShanghaiTechChina_B aimed to confirm the therapeutic effect of the over-expression epidermal growth factor (EGF) on E.coli in colitis microenvironment and hoped to utilize the peptide EGF secreted by the engineered bacteria to repair the colon tissue in patients.
· Our team established the inflammatory bowel disease (IBD) model to confirm the homing capability of the modified bone marrow derived mesenchymal stem cells (MSCs).
As a result, we assisted Team ShanghaiTechChina_B with animal model establishment to confirm the function of EGF derived from modified E.coli to prove the effect of the peptide in vivo.

Experiment Design
During the competition, we received the purified EGF peptide expressed by the engineered bacteria from Team ShanghaiTechChina_B. We established the IBD mice model and injected the EGF solution into the colon by cocolysis.
We referred to the related article to select the effective way (TNBS) to establish the model and examine the effect of EGF.[1][2]After IBD mice model establishment,
1. Selected several similar mice and weighed them on the second day of fasting.
2. Chose half of them for EGF solution enema as an experiment group, and the rest of them were dealt with normal saline as the control group.
3. Weighed each of them at the same time every day.
4. After the fifth day, sacrificed the mice by cervical dislocation and measured the length of colons.

Experiment Results

Table of Mice Weight
Sample Day 1 Day 2 Day 3 Day 4 Day 5
Unit:Gram
1 20.45 19.64 18.89 17.63 17.66
1 20.45 19.64 18.89 17.63 17.66
2 19.55 18.31 18.08 17.98 18.03
3 22.53 22.01 22.10 22.49 22.17
4 23.46 22.98 22.88 23.36 23.98

Figure 7.1

Figure 7.2 Figure 7.3

After injecting EGF solution into the colon by coloclysis, we were excited to see that the colon length and the weight loss improved a lot comparing with the IBD mice without injection, which indicated that EGF derived from modified E.coli had repair effect on the damaged colon in IBD model.

Reference: https://2016.igem.org/Team:ShanghaiTechChina_B/Collaborations#SYSU_MEDICINE


Conference with Team AHUT_China and NAU-China


On 28th, September, 2016, we were invited and held a conference on iGEM projects with Team AHUT_China and NAU-China. It was a great opportunity for us to publicize our team and projects in other cities. On this conference, we introduced great therapeutic effects of our engineered MSCs on inflammatory diseases and shared different opinions on cell therapy. We were excited to find that most audience were interested in this new chassis (MSCs) including its phenotype, function and low immunogenicity. After that, they raised questions on our biosafety of our engineered MSCs and gave some suggestion to us. We were pleased to communicate with people from different fields.

Figure 7.4

Participation in Newsletter held by XMU-China


Since it was the first time for our team, SYSU-MEDICINE, to participate in iGEM competition, we were eager to publicize us as well as our projects. Learning that Newsletter is a great stage for iGEMers to communicate and collaborate with each other, we showed ourselves by publishing our ideas, questionnaire, photos and so on. Surprisingly, we received some replies and suggestions.

Figure 7.5

Meet-up with Team NEU-China


It’s important to find new friends in iGEM. On 20th, August, the team leader of NEU-China happened to come to Guangzhou, China for a summer camp. We met him and bring him to sight-seeing around. Referring to collaboration, he mentioned that their team might need modelling help at later phase of the project. We discussed about assistance and drew a conclusion that if time and energy permit, we will help them with modelling.

Figure 7.6
In September, we had cooperation with them. Since our experiments had a lot of things in common, we cooperated in various aspects of the whole project. Especially, we had a deep discussion of the concept of modelling and exchanged views about the details, such as the way to predict the density of factors in the mice. At first, they were interested in our parts’confirmation in animal models, like fitting of fluorescence intensity. Later, they wanted to introduce that in their own models. We also gave them a little instruction about how to predict the factors in mice and analysis the data.

Communication with Team TMMU_China


At the very beginning, we talked about the Neutral Network with regards to its usage as classification, and regression model. We were excited to find out that both of our teams took similar ways to predict values. When realizing that there was a problem about how to define parameters, we both found a method to solve it. It was so happy to get the chance to communicate with someone who owned passion towards data analysis and we even promised to meet in Boston and attended some biostatistics classes in Harward.

Participation in CCiC
(Conference of China iGEMer Committee, 2016)


This year, Conference of China iGEMer Committee, 2016 is successfully held by School of Life Sciences, Sun Yat-sen University. (2nd~4th, September)
After invited, our team presented a poster and share our story in SYSU-CCiC conference. As a medical team, we brought a new therapeutical tool, mesenchymal stem cells, to participants, who were mostly not familiar with them. Surprisingly, we were excited that our project, MSCavalry: MSCs of next generation, attracted many attenders, which arose utmost praise and encouragement to us all.
SYSU-CCiC conference also provided us with an opportunity to communicate with other teams. During the conference, we found both advantages and disadvantages in our project and acquire significant suggestions, such as biosafety, ethics, efficiency of parts, etc. when we communicated with others. In next 2 months, we tried to solve them and change into better. We sincerely hoped conference next year can attract more teams and be more influential.

Figure 7.7

Collaboration with SYSU_China


As a new team for iGEM competition, we had confronted various problems since we established our team. Consequently, we asked SYSU-China, SYSU’s first iGEM team, for help, such as details of registration and how to understand judging criteria. As for part submission, they provided us backbone plasmid, pSB1C3. In addition, we gave them reagent for Interlab. We were pleased to learn from each other.

Figure 7.8
Reference can be seen in https://2016.igem.org/Team:SYSU-CHINA/HumanPractice/Collaboration


Reference:
[1] Wirtz S, Neufert C, Weigmann B, et al. Chemically induced mouse models of intestinal inflammation [J]. Nature protocols, 2007, 2(3): 541-546.
[2] Chen Q Q, Yan L, Wang C Z, et al. Mesenchymal stem cells alleviate TNBS-induced colitis by modulating inflammatory and autoimmune responses[J]. World J Gastroenterol, 2013, 19(29): 4702-4717.