Difference between revisions of "Team:UiOslo Norway"

 
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<h2 class="boxheader">The 2016 Oslo team</h2>
 
<h2 class="boxheader">The 2016 Oslo team</h2>
<p class="boxnotes">Hello! We are the 2016 iGEM team from the University of Oslo, which lies in Oslo, the heart of Norway. We are a total of 7 students who studies in different areas; informatics, pharmacy, nanotechnology and molecular biology. We have 2 supervisors, Dirk Linke and Eric de Muinck. If you want to get to know us better press the TEAM button.</p>
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<p class="boxnotes">We are the 2016 iGEM team from the University of Oslo, found in Oslo, the heart of Norway. We are a total of seven students with different areas of expertise; informatics, pharmacy, nanotechnology and molecular biology. We have two main supervisors, Dirk Linke and Eric de Muinck. If you want to get to know us better, press the TEAM button.</p>
 
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We are one out of two iGEM teams from Norway, along with NTNU, the team from Trondheim. iGEM is not a well known course in Norway but we certainly made sure that is changing this year. Read more about it under PRACTICES.
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Our project, URINETROUBLE, is about detecting Extended Spectrum β-lactamase (ESBL) producing bacteria in urinary tract infections. ESBL producing bacteria are antibiotic resistant bacteria which produce an enzyme called β-lactamase. β-lactamase cleaves the β-lactamring, a structure found in many of our most common antibiotics, thereby making these antibiotics ineffective. Effective detection of these bacteria would enable medical personnel to more accurately prescribe the right antibiotics the first time a patient comes in with an infection.
 
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<h2 class="boxheader">Antibiotic resistance</h2>
 
<h2 class="boxheader">Antibiotic resistance</h2>
<p class="boxnotes">This year we will try to involve us in the fight against antibiotic resistance. The World Health Organizaion (WHO), has listed antibiotic resistance as one of the biggest threat to global health. This threat affects all of us, independent of age and country. The consequences of antibiotic resistance are that smaller operations and treatable infections today, such as pneumonia and urinary tract infections, can become deadly.</p>
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<p class="boxnotes"> We pick up the mantle in the battle towards antibiotic resistance, officially listed by the WHO as one of the biggest threats to the world as we know it. This affects all of us, independent of age and country. The consequences of antibiotic resistance are that smaller operations and common infections that today are treatable, such as pneumonia and urinary tract infections, can become deadly.</p>
 
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The most effective way to keep antibiotic resistance away, is to STOP THE MISUSE OF ANTIBIOTICS. Antibiotics ONLY treat bacteria, so it won't help you if you have a cold. You can read more about antibiotic resistance on WHO's website.
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By improving diagnostics, unnecessary and futile use of antibiotics can be prevented, enabling us to contain the spread of
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resistant microbes before it is too late for all of us.
 
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<h2 class="boxheader">URINETROUBLE</h2>
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<h2 class="boxheader">Phonelab</h2>
<p class="boxnotes">We decided to name our project URINETROUBLE. Our project is about detecting ESBL resistant bacteria in urine, for people who have urinary tract infections. ESBL resistant bacteria are bacteria which secrete a substance called betalactamase. Betelactamase will cleave a ring in betalactam antibiotics and make them ineffective. This would affect what kind of antibiotics the doctor should presvribe to you, as betalactam antibiotics would be ineffective.</p>
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<p class="boxnotes">We present PhoneLab, a functioning diagnostic tool that could easily be commercialized. By combining our own unique hardware and software with traditional molecular biology and the power residing in modern smartphones, we have created the chassis for a mobile, easy-to-use and cheap detection tool. PhoneLab is a product that could play a role in changing the face of modern diagnostics.</p>
 
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Today the only way to know if a bacteria secrete betalactamase is to grow them overnight. Our goal is to detect those bacteria with a fast equipment which doctors can use in their offices and you can get the right antibiotics right away. </p> <span class="read_more"></span>
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Current detection methods are either too expensive, require expertise, take too much time and/or generate problematic waste. Therefore, many patients are prescribed antibiotics without being tested for the presence of antibiotic resistant microbes. PhoneLab can potentially eliminate these problems, allowing such tests to be done inexpensively, easily and safely within minutes. Thus, antibiotics can be prescribed in a more accurate way.</p> <span class="read_more"></span>
 
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Latest revision as of 21:35, 19 October 2016

Urinetrouble

The 2016 Oslo team

We are the 2016 iGEM team from the University of Oslo, found in Oslo, the heart of Norway. We are a total of seven students with different areas of expertise; informatics, pharmacy, nanotechnology and molecular biology. We have two main supervisors, Dirk Linke and Eric de Muinck. If you want to get to know us better, press the TEAM button.

Our project, URINETROUBLE, is about detecting Extended Spectrum β-lactamase (ESBL) producing bacteria in urinary tract infections. ESBL producing bacteria are antibiotic resistant bacteria which produce an enzyme called β-lactamase. β-lactamase cleaves the β-lactamring, a structure found in many of our most common antibiotics, thereby making these antibiotics ineffective. Effective detection of these bacteria would enable medical personnel to more accurately prescribe the right antibiotics the first time a patient comes in with an infection.

Antibiotic resistance

We pick up the mantle in the battle towards antibiotic resistance, officially listed by the WHO as one of the biggest threats to the world as we know it. This affects all of us, independent of age and country. The consequences of antibiotic resistance are that smaller operations and common infections that today are treatable, such as pneumonia and urinary tract infections, can become deadly.

By improving diagnostics, unnecessary and futile use of antibiotics can be prevented, enabling us to contain the spread of resistant microbes before it is too late for all of us.

Phonelab

We present PhoneLab, a functioning diagnostic tool that could easily be commercialized. By combining our own unique hardware and software with traditional molecular biology and the power residing in modern smartphones, we have created the chassis for a mobile, easy-to-use and cheap detection tool. PhoneLab is a product that could play a role in changing the face of modern diagnostics.

Current detection methods are either too expensive, require expertise, take too much time and/or generate problematic waste. Therefore, many patients are prescribed antibiotics without being tested for the presence of antibiotic resistant microbes. PhoneLab can potentially eliminate these problems, allowing such tests to be done inexpensively, easily and safely within minutes. Thus, antibiotics can be prescribed in a more accurate way.