You will find on this page the basic parts which have been designed by our team. For further details, you can also go on [http://www.parts.igem.org parts page] and have a look to the corresponding BioBrick's page.

This DNA sequence codes a [http://metacyc.org/gene?orgid=META&id=SCO2782 Lysine decarboxylase] (''Streptomyces'') which is an enzyme from the lyase family that converts lysine into cadaverine. The enzyme releases the carbonyl group of the lysin amino acid. Cadaverine (or 1,5-diaminopentane) is a primary diamine which renders the medium alkaline. The lysine decarboxylase is an enzyme whose synthesis is promoted by anaerobiosis and an acidic pH.  

This sequence codes a [http://metacyc.org/gene?orgid=META&id=SCO2783-MONOMER monooxygenase] which is an enzyme that incorporate one hydroxyl group into substrates in many metabolic pathways. In this reaction, the two atoms of dioxygen are reduced to one hydroxyl and one H2O molecule by the concomitant oxidation of NAD(P)H. It is also the second step in the production of Desferrioxamine B in ''Streptomyces'', allowing the transformation of cadeverine into N-hydroxycadaverine.

This coding sequence codes [http://metacyc.org/gene?orgid=META&id=SCO2785-MONOMER DesD] of ''Streptomyces coelicolor'', which is the last protein involved in the metabolic pathway of Desferrioxamine B. This enzyme is called Desferrioxamine biosynthesis protein or DesD and allows the transformation of N-acetyl N-hydroxycadaverine into Desferrioxamine B (by the transformation of 3 nucleoside triphosphate into 3 nucleoside 5'monophosphate-3-diphosphate).

[http://ecocyc.org/gene?orgid=ECOLI&id=EG11489-MONOMER CsgA] is the major and structural subunit of the curli fimbriae. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli are the major proteinaceous component of a complex extracellular matrix produced by many ''Enterobacteriaceae''. They were first discovered in the late 1980s on ''Escherichia coli'' strains that caused bovine mastitis, and have since been implicated in many physiological and pathogenic processes of ''E. coli'' and ''Salmonella'' spp. Curli fibers are involved in adhesion to surfaces, cell aggregation, and biofilm formation. They also mediate host cell adhesion and invasion, and they are potent inducers of the host inflammatory response. It has been shown that amyloid proteins, like curli, can bind some metals <ref name="metal_adhesion">[http://www.nature.com/nnano/journal/v11/n4/full/nnano.2015.310.html Sreenath Bolisetty and Raffaele Mezzenga 2016, Nature Nanotechnology]</ref> and thats why we wanted to use it in our project.