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| <link rel="icon" type="image/png" href="https://static.igem.org/mediawiki/2016/2/2a/T--SYSU-MEDICINE--logo_32%2A32.png" sizes="32x32"> | | <link rel="icon" type="image/png" href="https://static.igem.org/mediawiki/2016/2/2a/T--SYSU-MEDICINE--logo_32%2A32.png" sizes="32x32"> |
| <!-- Latest compiled and minified CSS --> | | <!-- Latest compiled and minified CSS --> |
− | <link href='//cdn.webfont.youziku.com/webfonts/nomal/92549/46882/57f3d7e1f629d81a5077d03f.css' rel='stylesheet' type='text/css' /> | + | <!--<link href='//cdn.webfont.youziku.com/webfonts/nomal/92549/46882/57f3d7e1f629d81a5077d03f.css' rel='stylesheet' type='text/css' />--> |
| <link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css" integrity="sha384-BVYiiSIFeK1dGmJRAkycuHAHRg32OmUcww7on3RYdg4Va+PmSTsz/K68vbdEjh4u" crossorigin="anonymous"> | | <link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css" integrity="sha384-BVYiiSIFeK1dGmJRAkycuHAHRg32OmUcww7on3RYdg4Va+PmSTsz/K68vbdEjh4u" crossorigin="anonymous"> |
| <!--jQuery--> | | <!--jQuery--> |
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| <style> | | <style> |
| /*font*/ | | /*font*/ |
| + | @font-face{font-family:"HelveticaNeueW02-45Ligh";src:url('//www.eyeem.com/css/fonts/88fcd49a-13c7-4d0c-86b1-ad1e258bd75d.eot?#iefix');src:url('//www.eyeem.com/css/fonts/88fcd49a-13c7-4d0c-86b1-ad1e258bd75d.eot?#iefix') format("eot"),url('//www.eyeem.com/css/fonts/9a2e4855-380f-477f-950e-d98e8db54eac.woff') format("woff"),url('//www.eyeem.com/css/fonts/fa82d0ee-4fbd-4cc9-bf9f-226ad1fcbae2.ttf') format("truetype"),url('//www.eyeem.com/css/fonts/48d599a6-92b5-4d43-a4ac-8959f6971853.svg#48d599a6-92b5-4d43-a4ac-8959f6971853') format("svg")} |
| *{ | | *{ |
− | font-family:"Helvetica-Neue-635ac8fbe16985","Arial",sans-serif; | + | font-family:"HelveticaNeueW02-45Ligh","Arial",sans-serif; |
− | letter-spacing: 0.1em; | + | letter-spacing: 0.4px; |
− | | + | line-height: 1.5em; |
| } | | } |
| #HQ_page h1,#HQ_page h2,#HQ_page h3,#HQ_page h4,#HQ_page h5,#HQ_page p{ | | #HQ_page h1,#HQ_page h2,#HQ_page h3,#HQ_page h4,#HQ_page h5,#HQ_page p{ |
− | font-family:"Helvetica-Neue-635ac8fbe16985","Arial",sans-serif; | + | font-family:"HelveticaNeueW02-45Ligh","Arial",sans-serif; |
| } | | } |
| #HQ_page p{ | | #HQ_page p{ |
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| #globalWrapper { | | #globalWrapper { |
| font-size: 100%; | | font-size: 100%; |
| + | padding-bottom: 0; |
| + | } |
| + | #content { |
| + | margin-bottom: 0; |
| } | | } |
− | /*.mw-content-ltr ol, .mw-content-rtl .mw-content-ltr ol{*/
| |
− | /*margin: 0 0.1;*/
| |
− | /*}*/
| |
| /*nav*/ | | /*nav*/ |
| .navbar { | | .navbar { |
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| height: 50px; | | height: 50px; |
| margin-bottom:0; | | margin-bottom:0; |
| + | z-index: 25; |
| } | | } |
| .navbar-inverse .navbar-brand { | | .navbar-inverse .navbar-brand { |
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| .navbar-inverse .navbar-nav>li>a { | | .navbar-inverse .navbar-nav>li>a { |
| color: #fff; | | color: #fff; |
− | font-weight:600; | + | font-weight:bold; |
| } | | } |
| .navbar-inverse .navbar-nav>li>a:hover { | | .navbar-inverse .navbar-nav>li>a:hover { |
| color: #999; | | color: #999; |
− | font-weight:600; | + | font-weight:bold; |
| + | } |
| + | .navbar-nav>li{ |
| + | top: -5px; |
| } | | } |
| /*.mw-content-ltr ul, .mw-content-rtl .mw-content-ltr ul {*/ | | /*.mw-content-ltr ul, .mw-content-rtl .mw-content-ltr ul {*/ |
− | /*margin: 0 0.1;*/
| + | /*margin: 0 0.1;*/ |
| /*}*/ | | /*}*/ |
| .dropdown-menu>li>a { | | .dropdown-menu>li>a { |
| font-weight: 600; | | font-weight: 600; |
| + | } |
| + | .third-level-list { |
| + | top: -10px; |
| + | left: 150px; |
| } | | } |
| /*carousel*/ | | /*carousel*/ |
| .carousel { | | .carousel { |
| margin-bottom: -30px; | | margin-bottom: -30px; |
| + | background-color: #f2f2f2; |
| } | | } |
| .carousel-control.left, .carousel-control.left:hover, .carousel-control.right, .carousel-control.right:hover{ | | .carousel-control.left, .carousel-control.left:hover, .carousel-control.right, .carousel-control.right:hover{ |
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| } | | } |
| .carousel-inner{ | | .carousel-inner{ |
− | top:-25px; | + | top:-35px; |
| } | | } |
| .carousel-caption { | | .carousel-caption { |
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| } | | } |
| /*video container*/ | | /*video container*/ |
− | .jumbotron { | + | #jumbo-video.jumbotron { |
| background-color: #f2f2f2; | | background-color: #f2f2f2; |
| padding-top: 0; | | padding-top: 0; |
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| .video-container>.video { | | .video-container>.video { |
| width: 100%; | | width: 100%; |
| + | margin-top: -10px; |
| } | | } |
| .video-container>.text{ | | .video-container>.text{ |
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| } | | } |
| .video-container>.text>.right p{ | | .video-container>.text>.right p{ |
− | line-height: 1.2em; | + | line-height: 1.5em; |
| font-size: 20px; | | font-size: 20px; |
| + | color: #333; |
| } | | } |
| .video-container>.text>.left h1{ | | .video-container>.text>.left h1{ |
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| font-size: 30px; | | font-size: 30px; |
| line-height: 1.3em; | | line-height: 1.3em; |
| + | margin-top: -20px; |
| + | color: #333; |
| + | } |
| + | #jumbo-footer.jumbotron { |
| + | padding-top: 20px; |
| + | padding-bottom: 30px; |
| + | margin-bottom: 0; |
| + | } |
| + | #jumbo-footer.jumbotron>.container { |
| + | width: 1300px; |
| + | } |
| + | #jumbo-footer.jumbotron>.container>.col-md-4{ |
| + | padding-left:10px; |
| + | padding-right:10px; |
| + | height: 250px; |
| + | } |
| + | #jumbo-footer.jumbotron>.container>.col-md-4 .img-container{ |
| + | height: 100%; |
| + | text-align:center; |
| + | overflow: hidden; |
| + | } |
| + | #jumbo-footer.jumbotron>.container>.col-md-4 img{ |
| + | width: 100%; |
| + | height: 100%; |
| + | margin-top: 0; |
| + | margin-left: 0; |
| + | } |
| + | #jumbo-footer.jumbotron>.container>.col-md-4 img:hover{ |
| + | width: 105%; |
| + | height: 105%; |
| + | margin-top: -6px; |
| + | margin-left: -8px; |
| + | cursor: pointer; |
| + | -webkit-transition: width 0.5s, height 0.5s, margin-top 0.5s, margin-left 0.5s; |
| + | -moz-transition: width 0.5s, height 0.5s, margin-top 0.5s, margin-left 0.5s; |
| + | -ms-transition: width 0.5s, height 0.5s, margin-top 0.5s, margin-left 0.5s; |
| + | -o-transition: width 0.5s, height 0.5s, margin-top 0.5s, margin-left 0.5s; |
| + | transition: width 0.5s, height 0.5s, margin-top 0.5s, margin-left 0.5s; |
| + | |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container{ |
| + | width: 1170px; |
| + | margin: 20px auto; |
| + | font-size: 18px; |
| + | color: #888; |
| + | /*font-weight: bold;*/ |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .line{ |
| + | height: 2px; |
| + | background-color: #bbb; |
| + | width: 100%; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact { |
| + | margin-top: 20px; |
| + | margin-left: 10px; |
| + | height: 140px; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .title{ |
| + | font-weight: bold; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact ul{ |
| + | list-style: none; |
| + | padding-left: 0; |
| + | margin-left: 0; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact ul.float-contact { |
| + | float:left; |
| + | width: 400px; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact ul li { |
| + | margin-top: 5px; |
| + | margin-bottom: 5px; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact ul li a img{ |
| + | width: 30px; |
| + | height: 30px; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact ul li a { |
| + | color: #888; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact ul li a:hover, #jumbo-footer.jumbotron>.footer-container .contact ul li a:active, #jumbo-footer.jumbotron>.footer-container .contact ul li a:focus { |
| + | color: #888; |
| + | text-decoration: none; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .contact .float-contact-right { |
| + | float:right; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .copyright{ |
| + | margin-top: 5px; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .copyright .text { |
| + | font-size: 16px; |
| + | float: left; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .copyright .icon{ |
| + | float: right; |
| + | } |
| + | #jumbo-footer.jumbotron>.footer-container .copyright .icon img { |
| + | width: 25px; |
| + | height: 25px; |
| + | } |
| + | #wechatModal .modal-dialog{ |
| + | width: 332px; |
| + | margin-top: 100px; |
| + | z-index: 2000; |
| + | } |
| + | /*img content*/ |
| + | .index-content .img-container{ |
| + | width: 1070px; |
| + | margin: 0 auto; |
| + | background-image: url("https://static.igem.org/mediawiki/2016/6/64/T--SYSU-MEDICINE--home-home-body-img2.png"); |
| + | background-repeat: no-repeat; |
| + | background-size: cover; |
| + | height: 1400px; |
| + | } |
| + | .index-content .img-container .my-icon{ |
| + | position:relative; |
| + | width: 60px; |
| + | height: 60px; |
| + | |
| + | } |
| + | .index-content .img-container .my-icon>img{ |
| + | position: absolute; |
| + | width: 100%; |
| + | height: 100%; |
| + | z-index:2; |
| + | } |
| + | .index-content .img-container .my-icon>img:hover{ |
| + | cursor: pointer; |
| + | } |
| + | .index-content .img-container .my-card{ |
| + | position: relative; |
| + | display: none; |
| + | width: 500px; |
| + | top: 25px; |
| + | left: 25px; |
| + | z-index: 10; |
| + | right: 470px; |
| + | } |
| + | .index-content .img-container .my-card>img{ |
| + | width: 100%; |
| + | } |
| + | .index-content .img-container .my-card>.card-text{ |
| + | position: relative; |
| + | left: 100px; |
| + | top: -72px; |
| + | |
| + | } |
| + | .index-content .img-container .my-card>.card-text>a{ |
| + | font-size: 20px; |
| + | color: dodgerblue; |
| + | } |
| + | #icon-1{ |
| + | left: 550px; |
| + | top: 110px; |
| + | } |
| + | #icon-2{ |
| + | left: 20px; |
| + | top: 120px; |
| + | } |
| + | #icon-3{ |
| + | left: 20px; |
| + | top: 120px; |
| + | } |
| + | #icon-4{ |
| + | left: 20px; |
| + | top: 120px; |
| + | } |
| + | #icon-5{ |
| + | left: 550px; |
| + | top: 100px; |
| + | } |
| + | #icon-6{ |
| + | left: 800px; |
| + | top: 530px; |
| + | } |
| + | #icon-7{ |
| + | left: 480px; |
| + | top: 820px; |
| + | } |
| + | #icon-8{ |
| + | left: 40px; |
| + | top: 730px; |
| } | | } |
| </style> | | </style> |
| + | <script type="text/javascript"> |
| + | $(document).ready(function() { |
| + | // wechat qr code |
| + | var canHide= true; |
| + | $('#wechatModal').on('show.bs.modal', function (e) { |
| + | // do something... |
| + | $("#wechatModal").after('<div class="modal-backdrop fade in"></div>'); |
| + | }); |
| + | $(".modal").click(function() { |
| + | // console.log("click"); |
| + | //$(this).remove(); |
| + | if (canHide) { |
| + | $(".modal-backdrop").remove(); |
| + | $('#wechatModal').modal('hide'); |
| + | } |
| + | }); |
| + | $(".modal-dialog").click(function() { |
| + | canHide = false; |
| + | }); |
| + | $(".modal").mousemove(function() { |
| + | canHide = true; |
| + | }); |
| + | $(".third-level-list").css("left", "120px"); |
| + | // third level menu on nav |
| + | $(".third-level-menu").mouseenter(function() { |
| + | console.log("mouse in"); |
| + | $(this).addClass("open"); |
| + | |
| + | }); |
| + | $(".third-level-menu").mouseleave(function() { |
| + | console.log("mouse in"); |
| + | $(this).removeClass("open"); |
| + | }); |
| + | $(".dropdown").mouseenter(function() { |
| + | $(this).addClass("open"); |
| + | }); |
| + | $(".dropdown").mouseleave(function() { |
| + | $(this).removeClass("open"); |
| + | }); |
| + | // card display |
| + | var containerTop = $(".img-container").offset().top; |
| + | var containerLeft= $(".img-container").offset().left; |
| + | var iconToCard = []; |
| + | for (var i = 1; i <= 8; ++i) { |
| + | var icon = $("#icon-" + i), |
| + | card = $("#card-" + i), |
| + | left, |
| + | top; |
| + | iconToCard.push(card); |
| + | left = icon.offset().left + icon.width() - containerLeft; |
| + | top = icon.offset().top - containerTop; |
| + | console.log("left: "+left+" top: "+top); |
| + | if (left > 700) { |
| + | console.log(card); |
| + | // card.css("right", "470"); |
| + | card.css("left", "auto"); |
| + | } |
| + | } |
| + | $(".my-icon").mouseenter(function() { |
| + | var id = $(this).attr("id"); |
| + | var num = parseInt(id.split("-")[1]); |
| + | $(this).children("img").css("z-index", "20"); |
| + | // iconToCard[num-1].css("display", "block"); |
| + | iconToCard[num-1].fadeIn('fast'); |
| + | }); |
| + | $(".my-icon").mouseleave(function() { |
| + | var id = $(this).attr("id"); |
| + | var num = parseInt(id.split("-")[1]); |
| + | |
| + | // iconToCard[num-1].css("display", "none"); |
| + | var t = $(this); |
| + | iconToCard[num-1].fadeOut({ |
| + | duration:'fast', |
| + | done: function() { |
| + | (function(t) { |
| + | t.children("img").css("z-index", "2"); |
| + | })(t); |
| + | } |
| + | }); |
| + | }); |
| + | }); |
| + | </script> |
| </head> | | </head> |
| <body> | | <body> |
− | <nav class="navbar navbar-inverse">
| + | <nav class="navbar navbar-inverse"> |
− | <div class="container-fluid">
| + | <div class="container-fluid"> |
− | <!-- Brand and toggle get grouped for better mobile display -->
| + | <!-- Brand and toggle get grouped for better mobile display --> |
− | <div class="navbar-header">
| + | <div class="navbar-header"> |
− | <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#bs-example-navbar-collapse-1" aria-expanded="false">
| + | <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#bs-example-navbar-collapse-1" aria-expanded="false"> |
− | <span class="sr-only">Toggle navigation</span>
| + | <span class="sr-only">Toggle navigation</span> |
− | <span class="icon-bar"></span>
| + | <span class="icon-bar"></span> |
− | <span class="icon-bar"></span>
| + | <span class="icon-bar"></span> |
− | <span class="icon-bar"></span>
| + | <span class="icon-bar"></span> |
− | </button>
| + | </button> |
− | <a class="navbar-brand" href="https://2016.igem.org/Team:SYSU-MEDICINE">
| + | <a class="navbar-brand" href="https://2016.igem.org/Team:SYSU-MEDICINE"> |
− | <img style="height: 40px; width: 40px; margin-top: -10px " src="https://2016.igem.org/wiki/skins/Igem/images/IGEM_white_letters.png">
| + | <img style="height: 40px; width: 40px; margin-top: -10px " src="https://2016.igem.org/wiki/skins/Igem/images/IGEM_white_letters.png"> |
− | </a>
| + | </a> |
− | <a class="navbar-brand" href="https://2016.igem.org/Team:SYSU-MEDICINE">SYSU-MEDICINE</a>
| + | <a class="navbar-brand" href="https://2016.igem.org/Team:SYSU-MEDICINE">SYSU-MEDICINE</a> |
− | </div>
| + | </div> |
| + | |
| + | <!-- Collect the nav links, forms, and other content for toggling --> |
| + | <div class="collapse navbar-collapse" id="bs-example-navbar-collapse-1"> |
| + | <ul class="nav navbar-nav navbar-right"> |
| + | <li class="active"><a href="https://2016.igem.org/Team:SYSU-MEDICINE">HOME</a></li> |
| + | <li class="dropdown"> |
| + | <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">PROJECT<span class="caret"></span></a> |
| + | <ul class="dropdown-menu"> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Description">Description</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Results">Results</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Protocol">Protocol</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Notebook">Notebook</a></li> |
| + | <li class="dropdown third-level-menu"> |
| + | <a href="#" class="dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">For Judgement <span class="glyphicon glyphicon-chevron-right"></span></a> |
| + | <ul class="third-level-list dropdown-menu"> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Proof">Proof of Concept</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Demonstrate">Demonstrate</a></li> |
| + | </ul> |
| + | </li> |
| + | </ul> |
| + | </li> |
| + | <li class="dropdown"> |
| + | <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">HUMAN PRACTICES<span class="caret"></span></a> |
| + | <ul class="dropdown-menu"> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Our_Story">Our Story</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Interview">Interview</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Ethics">Ethics</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Legislation">Legislation</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Products">Products</a></li> |
| + | <li class="dropdown third-level-menu"> |
| + | <a href="#" class="dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">For Judgement <span class="glyphicon glyphicon-chevron-right"></span></a> |
| + | <ul class="third-level-list dropdown-menu"> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/HP/Silver">Silver</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/HP/Gold">Gold</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Integrated_Practices">Integrated Practices</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Engagement">Engagement</a></li> |
| + | </ul> |
| + | </li> |
| + | </ul> |
| + | </li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Modeling">MODELING</a></li> |
| + | <li class="dropdown"> |
| + | <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">TEAM<span class="caret"></span></a> |
| + | <ul class="dropdown-menu"> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Team">Team</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Attributions">Attributions</a></li> |
| + | <li><a href="https://2016.igem.org/Team:SYSU-MEDICINE/Collaborations">Collaborations</a></li> |
| + | </ul> |
| + | </li> |
| | | |
− | <!-- Collect the nav links, forms, and other content for toggling -->
| + | <li class="dropdown"> |
− | <div class="collapse navbar-collapse" id="bs-example-navbar-collapse-1">
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− | <h2>MSCalvalry: MSCs of Next Generation</h2>
| + | <h1 style="font-size:80px">SYSU-MEDICINE</h1> |
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| + | <h1>MSCavalry</h1> |
| + | <h3>-----MSCs of<br/>Next Generation</h3> |
| </div> | | </div> |
− | <div class="text"> | + | <div class="right"> |
− | <div class="left"> | + | <p> |
− | <h1>MSCavalry</h1> | + | Inflammatory diseases are an increasing cause of disability and even fatality. |
− | <h3>-----MSCs of<br/>next generation</h3>
| + | Currently, apart from common treatments, MSCs therapy is a promising candidate for curing inflammatory diseases. |
− | </div>
| + | However, intravascular injected MSCs are criticized for its low homing efficiency and ambiguous distribution in human body. |
− | <div class="right">
| + | </p> |
− | <p>
| + | <p> |
− | Inflammatory diseases are an increasing cause of disability and even fatality.
| + | This year, MSCavalry: MSCs of Next Generation is coming. |
− | Currently, apart from common treatments, MSCs therapy is a promising candidate for curing inflammatory diseases.
| + | SYSU-MEDICINE decided to engineer a set of MSCs (homo sapiens) with higher accuracy and we hope that our project can pave the way for future MSCs clinical application. |
− | However, intravascular injected MSCs are criticized for its low homing efficiency and ambiguous distribution in human body.
| + | </p> |
− | </p>
| + | |
− | <p>
| + | |
− | This year, MSCavalry: MSCs of next generation is coming.
| + | |
− | SYSU-MEDICINE decide to engineer a set of MSCs (homo sapiens) with higher accuracy and we hope that our project can pave the way for future MSCs clinical application.
| + | |
− | </p>
| + | |
− | </div>
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− | <div class="column full_size" > | + | </div> |
− | <h2> Background </h2>
| + | |
− | <p>
| + | |
− | Mesenchymal stem cells (MSCs) are promising candidates for cell-based therapy to treat several diseases. Up to now, MSCs are used in over 600 ongoing clinical trials (June, 2016) like treating IBD, diabetes, encephalitis, etc. MSCs in current clinical use are isolated from bone marrow, adipose tissue and the umbilical cord. Different from the embryonic stem cells, MSCs have been shown to be highly immunosuppressive. In many studies, MSCs were found to suppress adaptive immune system as well as inherent immune system in multiple inflammatory diseases, which make MSCs a promising tool in treating inflammatory disease.
| + | |
− | <br>
| + | |
− | <br>
| + | |
− | Despite significant advantages, clinical trials of MSCs have produced mixed results which may significantly impede the advancement of MSC-based therapies. One of the most important reasons is for the inefficient homing ability of MSC that only a few MSC can indeed arrived the inflamed tissue after systematic administration and exert their immunomodulatory function.
| + | |
− | <br>
| + | |
− | <br>
| + | |
− | </p >
| + | |
− | | + | |
− | <h2>Current Design</h2>
| + | |
− | <p>
| + | |
− | This summer, next generation of MSCs are coming. We intend to construct a circuit of three plasmids that will be able to reinforce the locating function of MSCs. Previous studies have demonstrated that immune cells depend on chemokine receptors to accomplish directional moving. In our project, we are going to empower MSCs with chemokine receptors in order to ensure its effective homing. At the same time, with the purpose of locating in vivo MSC and assuring their arrival at the inflamed tissue, we will introduce several kinds of positioning system into our system and detect them by various methods.
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− | <div class="column half_size" > | + | <!-- Wechat QRCode Modal --> |
− | <div class="highlight"> | + | <div class="modal fade" id="wechatModal" tabindex="-1" role="dialog" aria-labelledby="myModalLabel" data-backdrop="false"> |
− | <h5> Styling your wiki </h5>
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− | <p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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− | <p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p> | + | |
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− | <h5> Wiki template information </h5> | + | <img style="height: 300px;width: 300px;" src="https://static.igem.org/mediawiki/2016/0/07/T--SYSU-MEDICINE--wechat-qrcode.png"> |
− | <p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2016.igem.org/Judging/Pages_for_Awards/Instructions">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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− | <h5> Editing your wiki </h5>
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− | <p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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− | <p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
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− | <h5>Tips</h5>
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− | <p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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− | <ul>
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− | <li>State your accomplishments! Tell people what you have achieved from the start. </li>
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− | <li>Be clear about what you are doing and how you plan to do this.</li>
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− | <li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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− | <li>Make sure information is easy to find; nothing should be more than 3 clicks away. </li>
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− | <li>Avoid using very small fonts and low contrast colors; information should be easy to read. </li>
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− | <li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2016.igem.org/Calendar">iGEM 2016 calendar</a> </li>
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− | <li>Have lots of fun! </li>
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− | </ul>
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− | </div>
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− | <h5>Inspiration</h5>
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− | <p> You can also view other team wikis for inspiration! Here are some examples:</p>
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− | <ul>
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− | <li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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− | <li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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− | <li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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− | <li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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− | <li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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− | <li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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− | </ul>
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− | </div>
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