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| − | <h2> <span class="mw-headline" id="PhyscoFilter_.E2.80.93_Clean_different."> The Boomerang system: synthetic machine for cancer therapy </span></h2>
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| − | <p>Despite recent treatment advancements, cancer is still a major cause of mortality worldwide. One of the fundamental problems preventing the development of effective therapy is the difficulty to target cancer cells exclusively.
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| − | <br />In Boomerang, we're engineering a genetic device based on a simple concept of AND logic gate: the activation of our CRISPR/Cas9-based system is dependent on the existence of two cancer-specific promoters that control the expression of Cas9 and gRNA, and the combination of these two will occur only in cancer cells. CRISPR/Cas9 system allows several applications of Boomerang: 1) disruption of genes essential for cancer survival; and 2) activation of suicide genes, or color proteins for cancer cell detection (e.g., for complete surgical removal). <br />Our system can be potentially designed according to unique characteristics of a patient's tumor, paving the way to personalized medicine. We hope that our strategy will change the approach to cancer treatments.</p>
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| − | <h2> <span class="mw-headline" id="Sponsors"> Sponsors </span></h2>
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| − | <a class="sponsor" href="http://www.tum.de/"><img src="https://static.igem.org/mediawiki/2013/9/97/Logo_TU-Muenchen_01.png" width="190px"></a>
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| − | <a class="sponsor" href="http://wzw.tum.de/"><img src="https://static.igem.org/mediawiki/2013/a/ac/Wzwlogo2.png" width="210px"></a>
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| − | <a class="sponsor" href="http://biologische-chemie.userweb.mwn.de/index.html"><img src="https://static.igem.org/mediawiki/2013/0/05/Unbenannt.PNG" width="190px"></a>
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| − | <a class="sponsor" href="http://www.daad.de/de/index.html"><img src="https://static.igem.org/mediawiki/2013/f/f7/TUM13_DAAD.jpg" width="120px"></a>
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| − | <a class="sponsor" href="http://www.geneious.com/"><img src="https://static.igem.org/mediawiki/2012/8/82/TUM_Geneious.png" width="190px"></a>
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| − | <a class="sponsor" href="http://www.eurofins.de/"><img src="https://static.igem.org/mediawiki/2013/b/bc/TUM_Eurofins.png" width="200px"></a>
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| − | <a class="sponsor" href="http://www.mathworks.de/"><img src="https://static.igem.org/mediawiki/2013/0/0c/TUM13_MathWorks.png" width="200px"></a>
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| − | <a class="sponsor" href="http://www.ika.com/"><img src="https://static.igem.org/mediawiki/2013/9/9d/TUM13_IKA.png" width="105px"></a>
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| − | <a class="sponsor" href="http://www.neb.com/"><img src="https://static.igem.org/mediawiki/2013/5/50/TUM13_Sponsor_NEB.jpg" width="155px"></a>
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| − | <a class="sponsor" href="http://www.promega.de/"><img src="https://static.igem.org/mediawiki/2013/f/f0/Promega-300.jpg" width="175px"></a>
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| − | <a class="sponsor" href="http://www.qiagen.com/"><img src="https://static.igem.org/mediawiki/2013/6/60/TUM13_Sponsor_Qiagen.png" width="100px"></a>
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| − | <a class="sponsor" href="http://www.iba-lifesciences.com/"><img src="https://static.igem.org/mediawiki/2013/9/9c/Iba_logo_claim_r_farbe.jpg" width="180px"></a>
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| − | <a class="sponsor" href="http://eu.idtdna.com/site/"><img src="https://static.igem.org/mediawiki/2013/1/13/Bonn_sponsor_idt.jpg" width="180px"></a>
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| − | <a class="sponsor" href="http://www.thermoscientific.com"><img src="https://static.igem.org/mediawiki/2013/e/ed/TUM13_Sponsor_logo_Thermo.jpg" width="140px"></a>
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| − | <a class="sponsor" href="http://www.erasynbio.eu/"><img src="https://static.igem.org/mediawiki/2013/5/58/Logo_ERASynBio.png" width="180px"></a>
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| − | <div class="visualClear"></div>
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| − | <a class="sponsor" style="float: none; margin: 10px auto;" href="http://www.roche.com/"><img src="https://static.igem.org/mediawiki/2015/b/b7/Medalcheck.png" height="80px"></a>
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| − | <a href="https://2015.igem.org/Team:BGU_Israel/Achievements">
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| − | <h2>Follow us:</h2>
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| − | <a id="adress" href="http://igembgu2015hp.wix.com/boomerang" target="blank"></a>
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| − | <!-- <a id="mail" href="mailto:igembgu2015@gmail.com"></a> -->
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| − | <a id="facebook" href="https://www.facebook.com/iGEMBGU" target="blank"></a>
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| − | <a id="twitter" href="https://twitter.com/BGU_iGEM" target="blank"></a>
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| − | <a id="youtube" href="https://www.youtube.com/watch?v=B8qtBpE3RDE" target="blank"></a>
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| − | <h2>Address:</h2>
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