Difference between revisions of "Team:USTC-Software"

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<div class="description">
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<h2>Project Description</h2>
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<p>What already done:</p>
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<p>We had a long-time brainstorm and find an appropriate project for the team. Although there're many aspects that can be solved by computing, things that can be done perfectly by us seem restricted. Before we finally decide which project to work on, we used to investigate those projects: </p>
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<ol>
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<li>GRN (genetic regulatory networks) research</li>
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<li>Software for NgAgo</li>
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<li>CNN application in protein picture analysis</li>
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<li>Biopano further development (Biopano 2.0)</li>
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<li>Aptamer analysis</li>
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</ol>
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<p>Finally, we discussed with our primary PI Haiyan Liu, and reached an agreement that Biopano has a better prospect than other alternatives. Moreover, a developed Biopano platform can be friendly to users who need to analyze genetic networks, which is part of project 1. After months of surveying, discussing, and brainstorming, our team selected Biopano 2.0 as the ultimate project.</p>
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<p><a href="https://2014.igem.org/Team:USTC-Software">Biopano</a> is an open source software based on visual editor servicing for editing large-scale gene networks. It helps in group work as well. Target gene can be licked to the existed network form the public database easily with the searching functions built in the software. The software also supports external plug-in, which allows users adding features they need. News in the second generation are:</p>
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<ol>
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<li>Real-time simulation for the expression of the gene network.</li>
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<li>To design the prototype gene lines with the truth table.</li>
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<li>To imply the gene network according to the result of the expression.</li>
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<li>To export into other software formats.</li>
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</ol>
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</div>
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<img src="http://placehold.it/800x300/d3d3d3/f2f2f2">
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<h2> Welcome to iGEM 2016! </h2>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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</div>
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<div class="column half_size" >
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<h5>Before you start: </h5>
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<p> Please read the following pages:</p>
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<ul>
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<li>  <a href="https://2016.igem.org/Requirements">Requirements page </a> </li>
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<li> <a href="https://2016.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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<li> <a href="https://2016.igem.org/Resources/Template_Documentation"> Template Documentation </a></li>
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</ul>
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</div>
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<div class="column half_size" >
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<div class="highlight">
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<h5> Styling your wiki </h5>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
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</div>
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</div>
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<div class="column full_size" >
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<h5> Wiki template information </h5>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2016.igem.org/Judging/Pages_for_Awards/Instructions">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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</div>
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<div class="column half_size" >
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<h5> Editing your wiki </h5>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
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</div>
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<div class="column half_size" >
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<h5>Tips</h5>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<ul>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2016.igem.org/Calendar">iGEM 2016 calendar</a> </li>
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<li>Have lots of fun! </li>
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</ul>
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</div>
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<div class="column half_size" >
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<h5>Inspiration</h5>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<ul>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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</ul>
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</div>
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<div class="column half_size" >
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<h5> Uploading pictures and files </h5>
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<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<div class="button_click"  onClick=" parent.location= 'https://2016.igem.org/Special:Upload '"
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UPLOAD FILES
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</div>
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</div>
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    <main data-sticky-container>
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        <div class="title-bar" data-responsive-toggle="navbar-global-mobile" data-hide-for="large">
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                    </ul>
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                <li>
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                    <a href="#">Human Practice</a>
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                    <ul class="menu vertical">
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                        <li><a href="#">One</a></li>
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                </li>
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                <li>
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                    <ul class="menu vertical">
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                        <li><a href="#">One</a></li>
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                        <li><a href="#">Three</a></li>
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                    <a href="#">Attributions</a>
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                    <ul class="menu vertical">
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                        <li><a href="#">One</a></li>
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                        <li><a href="#">Two</a></li>
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                        <li><a href="#">Three</a></li>
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            </ul>
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        </div>
  
 +
        <nav class="top-bar show-for-large" id="navbar-global">
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            <div class="top-bar-left">
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                <ul class="menu">
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                    <li class="menu-text">
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                        <a href="#">USTC-Software</a>
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                    </li>
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                </ul>
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            </div>
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            <div class="top-bar-left">
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                <ul class=" medium-horizontal vertical dropdown menu" data-responsive-menu="accordion medium-dropdown">
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                </ul>
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            </div>
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            <div class="top-bar-right">
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                <ul class="dropdown menu" data-dropdown-menu>
 +
                    <li>
 +
                        <a href="#">Home</a>
 +
                        <ul class="menu vertical">
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                            <li><a href="#">One</a></li>
 +
                            <li><a href="#">Two</a></li>
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                            <li><a href="#">Three</a></li>
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                            <li><a href="#">Another action</a></li>
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                        </ul>
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                    </li>
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                    <li>
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                        <a href="#">Project</a>
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                        <ul class="menu vertical">
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                            <li><a href="#">One</a></li>
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                            <li><a href="#">Two</a></li>
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                            <li><a href="#">Three</a></li>
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                            <li><a href="#">Another action</a></li>
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                        </ul>
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                    </li>
 +
                    <li>
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                        <a href="#">Technology</a>
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                        <ul class="menu vertical">
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                            <li><a href="#">One</a></li>
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                            <li><a href="#">Two</a></li>
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                            <li><a href="#">Three</a></li>
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                        </ul>
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                    </li>
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                    <li>
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                        <a href="#">Human Practice</a>
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                        <ul class="menu vertical">
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                            <li><a href="#">One</a></li>
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                            <li><a href="#">Two</a></li>
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                            <li><a href="#">Three</a></li>
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                    </li>
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                    <li>
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                        <a href="#">Team</a>
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                        <ul class="menu vertical">
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                            <li><a href="#">One</a></li>
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                    </li>
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                        <a href="#">Attributions</a>
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                        <ul class="menu vertical">
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                            <li><a href="#">One</a></li>
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                            <li><a href="#">Two</a></li>
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                    </li>
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            </div>
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        </nav>
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        <div id="main-img-container">
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            <div class="orbit" role="region" aria-label="Some Pictures" data-orbit data-options="animInFromLeft:fade-in; animInFromRight:fade-in; animOutToLeft:fade-out; animOutToRight:fade-out;" data-timer-delay="3000">
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                <ul class="orbit-container">
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                    <button class="orbit-previous"><span class="show-for-sr">Previous Slide</span>&#9664;&#xFE0E;</button>
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                    <button class="orbit-next"><span class="show-for-sr">Next Slide</span>&#9654;&#xFE0E;</button>
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                    <li class="is-active orbit-slide">
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                        <img class="orbit-image" src="imgs/USTC-index-background-4.jpg" alt="image">
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                        <h3 style="position:absolute;top:50vh;left:50vw;">Head</h3>
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                        <!--<figcaption class="orbit-caption">image, the final frontier.</figcaption>-->
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                        <img class="orbit-image" src="imgs/nature.jpg" alt="image">
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                        <!--<figcaption class="orbit-caption">Lets Rocket!</figcaption>-->
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                    <li class="orbit-slide">
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                        <img class="orbit-image" src="imgs/EveryOne.jpg" alt="image">
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                        <!--<figcaption class="orbit-caption">Encapsulating</figcaption>-->
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                    <!--<li class="orbit-slide">-->
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                    <!--<img class="orbit-image" src="imgs/USTC-index-background-4.jpg" alt="image">-->
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                    <!--<figcaption class="orbit-caption">Outta This World</figcaption>-->
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                    <!--</li>-->
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                <!--
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                <nav class="orbit-bullets">
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                    <button class="is-active" data-slide="0"><span class="show-for-sr">First slide details.</span><span class="show-for-sr">Current Slide</span></button>
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                    <button data-slide="1"><span class="show-for-sr">Second slide details.</span></button>
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                    <button data-slide="2"><span class="show-for-sr">Third slide details.</span></button>
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                    <button data-slide="3"><span class="show-for-sr">Fourth slide details.</span></button>
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        <div data-sticky-container id="sticky-wrapper">
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            <nav class="top-bar show-for-large sticky" id="navbar-head" data-sticky data-top-anchor="sticky-wrapper" data-stick-to="top" data-margin-top="0">
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                <div class="top-bar-title">
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                    <ul class="menu">
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                        <li class="menu-text" id="nav-top">
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                            <a href="#">USTC-Software</a>
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                        </li>
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                    </ul>
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                </div>
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                <div class="top-bar-right">
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                    <ul class="menu" data-magellan>
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                        <!--
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                        <li id="nav-link1">
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                            <h3>Logic</h3>
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                        </li>
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                        <li id="nav-link2">
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                            <h3>Gene Network</h3>
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                        </li>
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                        <li id="nav-link3">
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                            <h3>Simulation</h3>
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                        </li>
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                        <li id="nav-link4">
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                            <h3>Analysis</h3>
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                        </li>
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                        <li id="nav-link5">
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                            <h3>DNA</h3>
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                        </li>
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                        -->
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                        <li id="nav-link1"><a href="#link1">Logic</a></li>
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                        <li id="nav-link2"><a href="#link2">Gene Network</a></li>
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                        <li id="nav-link3"><a href="#link3">Simulation</a></li>
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                        <li id="nav-link4"><a href="#link4">Analysis</a></li>
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                        <li id="nav-link5"><a href="#link5">DNA</a></li>
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                    </ul>
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                </div>
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            </nav>
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        </div>
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        <section id="main-section">
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            <div class="row animation" id="link1" data-magellan-target="link1">
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                <div class="small-12 columns">
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                    <h2 style="text-align:center;color:#3883d8;">An Extendable Platform For Synthetic Biology Researchers</h2>
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                </div>
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                <div class="small-12 large-6 columns silde-in-left" id="text1">
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                    <p>合成生物学研究者在工作中经常需要使用到许多不同来源的数据,例如蛋白编码DNA,基因表达调控原件,非编码RNA,转录调节蛋白等,在同一个课题中需要同时对这些相关联的原件进行排列,描述它们的关系进行,并以此进行对相关联的原件同时进行修改。我们因此希望设计一个软件平台biohub,合成生物学研究者可以使用一个平台就可以统一编辑多种相关联的不同类型的原件及其属性,并对一个课题进行系统性的管理。同时,考虑到同一课题组的合成生物学研究者常常一同管理一个课题,因此biohub提供了服务器端与网页形式的服务,服务器端假设在实验室公共服务器上,而用户则通过浏览器访问biohub。
 +
                        当研究中需要对大规模基因网络进行调控时,一个友好的图形用户界面显得尤为重要,它可以帮助用户迅速理清繁杂的网络,找到需要的部分。在这一点上,biohub继承了往年ustc-software队伍biopano的工作,并进一步优化了图形界面,使他看起来更加赏心悦目。同时相对于往届工作 biohub成为了一个插件系统,并添加了许多自带小工具插件,例如快速查询数据库,一键blast,通过基因调控关系求解并显示基因表达的的结果,以方便用户使用。所有用户都可以依据自己的研究习惯与喜好添加,删除,以及自己编写插件。</p>
 +
                </div>
 +
                <div class="small-12 large-6 columns inner-text-container slide-in-right" id="animation1">
 +
                    <img src="imgs/animation1.png">
 +
                    <h3 class="inner-text">some image</h3>
 +
                </div>
 +
            </div>
 +
            <div class="row" id="link2" data-magellan-target="link2">
 +
                <div class="small-12 columns">
 +
                    <h2 style="text-align:center;color:#38ced7"><span>See the detailed structure of a designed gene circuit</span></h2>
 +
                </div>
 +
                <div class="small-12 columns">
 +
                    <p>Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder
 +
                        speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.</p>
 +
                    <p>Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock.
 +
                        Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.</p>
 +
                    <p>Pork loin tail pork belly shank ham. Kielbasa venison ham, short loin ham hock beef ribs tri-tip ball tip pork belly. Ribeye sirloin sausage tenderloin hamburger. Strip steak tongue turkey, andouille bacon beef ribs venison. T-bone
 +
                        ball tip bresaola fatback, ground round meatball chicken sausage tongue pork chop leberkas sirloin jerky shank bacon. Turducken sirloin cow shankle pig, leberkas venison boudin pastrami.</p>
 +
                    <p>Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick
 +
                        pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin
 +
                        short ribs pig, rump tail chuck turducken.
 +
                    </p>
 +
                    <p>Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.</p>
 +
                    <p>Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder
 +
                        speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.</p>
 +
                </div>
 +
                <!-- slides-->
 +
            </div>
  
 +
            <div class="row animation" id="link3" data-magellan-target="link3">
 +
                <div class="small-12 columns">
 +
                    <h2 style="text-align:center;color:#22d659">Get concentration-time simulation results</h2>
 +
                </div>
 +
                <div class="small-12 large-6 columns inner-text-container" id="animation2">
 +
                    <img src="imgs/animation1.png">
 +
                    <h3 class="inner-text">some image</h3>
 +
                </div>
 +
                <div class="small-12 large-6 columns" id="text2">
 +
                    <p>Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick
 +
                        pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin
 +
                        short ribs pig, rump tail chuck turducken.</p>
 +
                    <p>Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.</p>
 +
                    <p>Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock.
 +
                        Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.</p>
 +
                </div>
 +
            </div>
 +
            <div class="row" id="link4" data-magellan-target="link4">
 +
                <div class="small-12 columns">
 +
                    <h2 style="text-align:center;color:#953543">Get robustness and sensitivity analysis</h2>
 +
                </div>
 +
                <div class="small-12 columns">
 +
                    <p>Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock.
 +
                        Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.</p>
 +
                    <p>Pork loin tail pork belly shank ham. Kielbasa venison ham, short loin ham hock beef ribs tri-tip ball tip pork belly. Ribeye sirloin sausage tenderloin hamburger. Strip steak tongue turkey, andouille bacon beef ribs venison. T-bone
 +
                        ball tip bresaola fatback, ground round meatball chicken sausage tongue pork chop leberkas sirloin jerky shank bacon. Turducken sirloin cow shankle pig, leberkas venison boudin pastrami.</p>
 +
                    <p>Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick
 +
                        pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin
 +
                        short ribs pig, rump tail chuck turducken.
 +
                    </p>
 +
                    <p>Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.</p>
 +
                    <p>Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder
 +
                        speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.</p>
 +
                    <p>Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock.
 +
                        Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.</p>
 +
                </div>
 +
            </div>
 +
            <div class="row" id="link5" data-magellan-target="link5">
 +
                <div class="small-12 columns">
 +
                    <h2 style="text-align:center;">Get the DNA sequence!</h2>
 +
                </div>
 +
                <div class="col-md-10">
 +
                    <p>Pork loin tail pork belly shank ham. Kielbasa venison ham, short loin ham hock beef ribs tri-tip ball tip pork belly. Ribeye sirloin sausage tenderloin hamburger. Strip steak tongue turkey, andouille bacon beef ribs venison. T-bone
 +
                        ball tip bresaola fatback, ground round meatball chicken sausage tongue pork chop leberkas sirloin jerky shank bacon. Turducken sirloin cow shankle pig, leberkas venison boudin pastrami.</p>
 +
                    <p>Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick
 +
                        pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin
 +
                        short ribs pig, rump tail chuck turducken.
 +
                    </p>
 +
                    <p>Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.</p>
 +
                </div>
 +
            </div>
 +
            <div class="img-fixed-position content-container" style="background-image:url(imgs/EveryOne.jpg);">
 +
            </div>
 +
            <div class="row">
 +
                <div class="small-12 columns">
 +
                    <p>Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder
 +
                        speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.</p>
 +
                    <p>Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock.
 +
                        Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.</p>
 +
                    <p> Users have the freedom to drag specific BioBricks on our canvas and combine them into a functional gene circuit. Then the DNA sequence and other information of the designed circuit are available for users to check and download.</p>
 +
                    <p>
 +
                        Wet lab protocols are partly incorporated into our DNA sequences which may make the design better and applicable in laboratories.
 +
                    </p>
 +
                </div>
 +
            </div>
 +
        </section>
 +
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An Extendable Platform For Synthetic Biology Researchers

合成生物学研究者在工作中经常需要使用到许多不同来源的数据,例如蛋白编码DNA,基因表达调控原件,非编码RNA,转录调节蛋白等,在同一个课题中需要同时对这些相关联的原件进行排列,描述它们的关系进行,并以此进行对相关联的原件同时进行修改。我们因此希望设计一个软件平台biohub,合成生物学研究者可以使用一个平台就可以统一编辑多种相关联的不同类型的原件及其属性,并对一个课题进行系统性的管理。同时,考虑到同一课题组的合成生物学研究者常常一同管理一个课题,因此biohub提供了服务器端与网页形式的服务,服务器端假设在实验室公共服务器上,而用户则通过浏览器访问biohub。 当研究中需要对大规模基因网络进行调控时,一个友好的图形用户界面显得尤为重要,它可以帮助用户迅速理清繁杂的网络,找到需要的部分。在这一点上,biohub继承了往年ustc-software队伍biopano的工作,并进一步优化了图形界面,使他看起来更加赏心悦目。同时相对于往届工作 biohub成为了一个插件系统,并添加了许多自带小工具插件,例如快速查询数据库,一键blast,通过基因调控关系求解并显示基因表达的的结果,以方便用户使用。所有用户都可以依据自己的研究习惯与喜好添加,删除,以及自己编写插件。

some image

See the detailed structure of a designed gene circuit

Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.

Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock. Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.

Pork loin tail pork belly shank ham. Kielbasa venison ham, short loin ham hock beef ribs tri-tip ball tip pork belly. Ribeye sirloin sausage tenderloin hamburger. Strip steak tongue turkey, andouille bacon beef ribs venison. T-bone ball tip bresaola fatback, ground round meatball chicken sausage tongue pork chop leberkas sirloin jerky shank bacon. Turducken sirloin cow shankle pig, leberkas venison boudin pastrami.

Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin short ribs pig, rump tail chuck turducken.

Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.

Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.

Get concentration-time simulation results

some image

Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin short ribs pig, rump tail chuck turducken.

Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.

Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock. Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.

Get robustness and sensitivity analysis

Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock. Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.

Pork loin tail pork belly shank ham. Kielbasa venison ham, short loin ham hock beef ribs tri-tip ball tip pork belly. Ribeye sirloin sausage tenderloin hamburger. Strip steak tongue turkey, andouille bacon beef ribs venison. T-bone ball tip bresaola fatback, ground round meatball chicken sausage tongue pork chop leberkas sirloin jerky shank bacon. Turducken sirloin cow shankle pig, leberkas venison boudin pastrami.

Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin short ribs pig, rump tail chuck turducken.

Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.

Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.

Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock. Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.

Get the DNA sequence!

Pork loin tail pork belly shank ham. Kielbasa venison ham, short loin ham hock beef ribs tri-tip ball tip pork belly. Ribeye sirloin sausage tenderloin hamburger. Strip steak tongue turkey, andouille bacon beef ribs venison. T-bone ball tip bresaola fatback, ground round meatball chicken sausage tongue pork chop leberkas sirloin jerky shank bacon. Turducken sirloin cow shankle pig, leberkas venison boudin pastrami.

Cow fatback short loin, hamburger speck jowl turducken capicola ham hock. Hamburger corned beef strip steak shank filet mignon, jerky capicola chicken jowl ribeye pork ham hock ground round bresaola. Jowl ribeye kielbasa drumstick pork belly leberkas. Spare ribs fatback shankle, hamburger meatloaf sausage pork loin andouille pork kielbasa. Pancetta shank tongue, leberkas turducken shoulder rump meatball pork belly pig hamburger brisket biltong. Tenderloin short ribs pig, rump tail chuck turducken.

Cow tri-tip pork loin salami corned beef. T-bone turkey ham frankfurter, brisket cow chicken bacon rump sirloin. Pancetta ribeye salami leberkas speck shank. Ribeye prosciutto swine venison speck beef.

Biltong pastrami kielbasa short ribs, turducken shoulder pork chop boudin ground round speck cow. Fatback leberkas shank hamburger, tail pork belly tongue bresaola short ribs corned beef speck tri-tip ribeye. Filet mignon shoulder speck pastrami. Ham hock turducken corned beef shankle. Meatloaf shankle sausage boudin, shank flank turducken tenderloin pancetta ball tip. Biltong boudin jowl drumstick pig.

Sirloin venison bresaola andouille pastrami short ribs. Short loin cow capicola tail ham hock leberkas. Frankfurter meatloaf capicola, swine ball tip jerky pork loin pork belly cow ribeye brisket strip steak jowl beef ribs ham hock. Pastrami ham hock rump turkey, pork belly capicola jerky. Turkey chuck beef, bresaola filet mignon jerky tri-tip pastrami. Bacon capicola jowl fatback short ribs. Speck shankle bacon chuck.

Users have the freedom to drag specific BioBricks on our canvas and combine them into a functional gene circuit. Then the DNA sequence and other information of the designed circuit are available for users to check and download.

Wet lab protocols are partly incorporated into our DNA sequences which may make the design better and applicable in laboratories.