Difference between revisions of "Team:BostonU HW/CSS"
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| − | <h1>BU 2016</h1> | + | <h1></br> BU 2016</h1> |
<h3>iGem Special Track: Hardware</h3> | <h3>iGem Special Track: Hardware</h3> | ||
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Microfluidic devices consist of valves and channels that can manipulate small volumes of liquids laid out in a customizable fashion. Using this, scientists can reduce reagent costs, automate experiments, and attain a high and more precise throughput with predictable fluid flow. | Microfluidic devices consist of valves and channels that can manipulate small volumes of liquids laid out in a customizable fashion. Using this, scientists can reduce reagent costs, automate experiments, and attain a high and more precise throughput with predictable fluid flow. | ||
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However, due to the technical agility, high cost and long build time, microfluidics are not very highly used. The current method of photolithography costs $80,000 and an expert to use. | However, due to the technical agility, high cost and long build time, microfluidics are not very highly used. The current method of photolithography costs $80,000 and an expert to use. | ||
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<h2 align="center"> Where can we use microfluidics? </h2> | <h2 align="center"> Where can we use microfluidics? </h2> | ||
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| − | + | - Synthetic Biology. Reference: | |
| + | <a href="http://pubs.rsc.org/en/content/articlepdf/2014/lc/c4lc00509k"> 'Lab on a Chip', 2014</a> | ||
<br> | <br> | ||
| − | Experiments to monitor precise control of the number and concentration of input. | + | - Experiments to monitor precise control of the number and concentration of input. Reference: |
| + | <a href="http://stke.sciencemag.org/content/5/213/ra17.full"> 'Diverse Sensitivity Thresholds in Dynamic Signaling Response by Social Amoebae', 2012</a> | ||
<br> | <br> | ||
| − | Single-cell tracking. | + | - Single-cell tracking. Reference: |
| + | <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836382"> 'Microfluidics for Synthetic Biology: From Design to Execution'</a> | ||
<br> | <br> | ||
| − | Microchemostat: environment control. | + | - Microchemostat: environment control. Reference: |
| + | <a href="http://science.sciencemag.org/content/309/5731/137.full">'Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat', 2005</a> | ||
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Revision as of 21:23, 26 June 2016
Fluigi is a specify, design, build workflow to aid microfluidic device development.
Background in Microfluidics
Microfluidic devices consist of valves and channels that can manipulate small volumes of liquids laid out in a customizable fashion. Using this, scientists can reduce reagent costs, automate experiments, and attain a high and more precise throughput with predictable fluid flow.
However, due to the technical agility, high cost and long build time, microfluidics are not very highly used. The current method of photolithography costs $80,000 and an expert to use.
Here's where Fluigi comes into use!
Here's where Fluigi comes into use!
Where can we use microfluidics?
- Synthetic Biology. Reference: 'Lab on a Chip', 2014
- Experiments to monitor precise control of the number and concentration of input. Reference: 'Diverse Sensitivity Thresholds in Dynamic Signaling Response by Social Amoebae', 2012
- Single-cell tracking. Reference: 'Microfluidics for Synthetic Biology: From Design to Execution'
- Microchemostat: environment control. Reference: 'Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat', 2005
