Difference between revisions of "Team:Aachen"

Line 1: Line 1:
−
{{Aachen}}
+
<html >
−
<html>
+
<head>
 +
  <title>Welcome to iGEM Aachen 2016</title>
 +
  <meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
 +
  <meta http-equiv="X-UA-Compatible" content="IE=edge">
 +
<meta charset="utf-8">
 +
<meta name="description" content="">
 +
<meta name="viewport" content="width=device-width, initial-scale=1.0">
 +
<link href="Team:Aachen/style.css" rel="stylesheet" media="screen,projection">
 +
 +
<!-- light Slider -->
 +
<link rel="stylesheet"  href="Team:Aachen/lightslider.css"/>
 +
<style>
 +
ul{
 +
list-style: none outside none;
 +
padding-left: 0;
 +
margin: 0;
 +
}
 +
.content-slider li{
 +
background-color: #ed3020;
 +
text-align: center;
 +
color: #FFF;
 +
}
 +
.content-slider h3 {
 +
margin: 0;
 +
padding: 70px 0;
 +
}
  
−
<div class="column full_size" >
+
</style>
  
−
<img src="https://static.igem.org/mediawiki/2016/4/49/Aachen_Team2016.jpeg" align="center"  >
+
</head>
−
</div>
+
  
−
<div class="column full_size" >
+
<body>
−
<h2> Welcome visitor of the iGEM Team Aachen’s Wiki of 2016! </h2>
+
<a href="#" class="go-top"><i class="fa fa-chevron-circle-up fa-3x"></i></a>
−
<h4> Project Description </h4>
+
<div class="header_area " >
−
<p> The following text shall inform you about what we will try to achieve this year and give you a little insight about how and why we chose the topic we will work on.<br></br>
+
<div class=" header ">
−
In our brainstorming phase, the initial idea that met with broad approval in the team, included reversible inhibition of an enzyme to improve a lab method. So we dived into research about enzyme inhibition and came up with several possibilities and approaches. Especially "Photocaging", a method using photoliable molecules to reversibly inactivate all kinds of compounds and reactivate them with light, really awakened interest in all of us. Along with knowledge about inhibition, more and more application possibilities occurred and gained shape as we talked to several supporters in academics as well as in industry. <br></br>
+
<div class=" floatleft">
−
In the end, the project that suits the iGEM spirit most and offers a highly educational and interesting experience for us, was the inhibition of a protease for washing detergents.
+
<nav class="main-navigation ">
−
<br></br>
+
<ul>
−
So far, proteases in washing detergents are being inhibited by boric acid and tons of it are needed every year. Its handling in this scale is complicated and additionally, the ECHA (European Chemicals Agency) classified this chemical as a substance of very high concern. If we can make our idea work, the protease in the washing detergents would be produced inactive and could be activated with a small, inexpensive device that can be used with any normal washing machine. Thus, the amount of chemical needed could be reduced by a great deal, as only one molecule per enzyme is necessary for inhibition. That would make a difference, especially for chemical workers, who have to handle tons of boric acid, but also for every household and sewage disposal.
+
<li>
−
<br></br>
+
<img src="images/T--Aachen--logo_2016.png" alt="logo" >
−
As a side project to the development of the “uncaging” device for the washing machine, our engineers will also work on an affordable “Dark Bench” that will make sterile handling of light-sensitive chemicals, needed for our work, more easy.
+
<ul class="sub-menu" style="width: auto">
−
</p>
+
<li align="middle"><a href="https://2015.igem.org/Team:Aachen" style="text-decoration: none ">
 +
<img src="images/T--Aachen--logo_2015.png" alt="logo" ></a>
 +
</li>
 +
<li align="middle"><a href="https://2014.igem.org/Team:Aachen" style="text-decoration: none" >
 +
<img src="images/T--Aachen--logo_2014.png" alt="logo"></a>
 +
</li>
 +
</ul>
 +
</li>
 +
</ul>
 +
</nav>
 +
</div>
 +
<div class="mainmenu floatright ">
 +
<nav class="main-navigation pull-right hidden-xs hidden-sm">
 +
<ul>
 +
<li ><a href="index.html" class='active-page'>Home</a></li>
 +
<li><a href="project.html" class="has-submenu">Project Idea</a>
 +
<ul class="sub-menu">
 +
<li><a href="project.html#ecoli" >E-coli-Subgroup</a></li>
 +
<li><a href="project.html#yeast">Yeast-Subgroup</a></li>
 +
<li><a href="project.html#synthetase">Synthetase-Subgroup</a></li>
 +
<li><a href="project.html#hardware" >Hardware-Subgroup</a></li>
 +
<li><a href="glossary.html">Glossary</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="lab.html" class="has-submenu">Lab</a>
 +
<ul class="sub-menu">
 +
<li><a href="labBook.html">Lab Book</a></li>
 +
<li><a href="collaboration.html">Collaboration</a></li>
 +
<li><a href="parts.html">Parts&nbsp;</a></li>
 +
<li><a href="safety.html">Safety</a></li>
 +
<li><a href="interLab.html">Interlab Study</a></li>
 +
<li><a href="protocol.html">Protocols/Methods</a></li>
 +
<li><a href="useable.html">Useables</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="humanPractise.html" class="has-submenu">Human Practices</a>
 +
<ul class="sub-menu">
 +
<li><a href="engagement.html">Engagement</a></li>
 +
<li><a href="integratedPractise.html " >Integrated Practices</a></li>
 +
<li><a href="beyondBasic.html ">Beyond the Basics</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="achievements.html" class="has-submenu">Achievements</a>
 +
<ul class="sub-menu">
 +
<li><a href="medalCriteria.html " >Medal Criteria</a></li>
 +
<li><a href="result.html " >Result</a></li>
 +
<li><a href="proofConcept.html " >Proof Of Concept</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="Team.html" class="has-submenu">Team</a>
 +
<ul class="sub-menu">
 +
<li><a href="Team.html#members">Members</a></li>
 +
<li><a href="Team.html#advisors">Advisors</a></li>
 +
<li><a href="Team.html#supervisor">Supervisor</a></li>
 +
<li><a href="attribution.html">Attribution</a></li>
 +
<li><a href="supporters.html">Supporters</a></li>
 +
</ul>
 +
</li>
 +
</ul>
 +
</nav>
 +
</div>
 +
</div>
 +
</div>
  
−
</div>
+
<div class="header_bottom_area"></div>
 +
<div class="main_content_area ">
 +
<div class=" content_area structure">
 +
<ul id="image-gallery" class="gallery list-unstyled cS-hidden">
 +
 
 +
<li  data-thumb="images/thumbs/T--Aachen--001.jpg">
 +
<img src="images/T--Aachen--001.jpg" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--002.jpg">
 +
<img src="images/T--Aachen--002.jpg" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--003.jpg">
 +
<img src="images/Aachen_2016_3.jpg" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--004.jpg">
 +
<img src="images/T--Aachen--004.jpg" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--005.jpg">
 +
<img src="images/T--Aachen--005.JPG" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--006.jpg">
 +
<img src="images/T--Aachen--006.JPG" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--007.jpg" >
 +
<img src="images/T--Aachen--007.jpg" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--008.jpg">
 +
<img src="images/T--Aachen--008.jpg" />
 +
</li>
 +
<li data-thumb="images/thumbs/T--Aachen--009.jpg">
 +
<img src="images/T--Aachen--009.JPG" />
 +
</li>
 +
</ul>
 +
 
 +
 
 +
</div>
 +
<div style="margin-bottom:50px;"></div>
 +
 
 +
<div class=" content_area structure">
 +
 
 +
<h2>Project Description</h2>
 +
<p> The following text shall inform you about what we will try to achieve this year and give you a little insight
 +
about how and why we chose the topic we will work on. <br/>
 +
In our brainstorming phase, the initial idea that met with broad approval in the team, included reversible inhibition of
 +
an enzyme to improve a lab method. So we dived into research about enzyme inhibition and came up with several possibilities
 +
and approaches. Especially "Photocaging", a method using photoliable molecules to reversibly inactivate all kinds of compounds
 +
and reactivate them with light, really awakened interest in all of us. Along with knowledge about inhibition, more and more
 +
application possibilities occurred and gained shape as we talked to several supporters in academics as well as in industry.
 +
<br/>
 +
In the end, the project that suits the iGEM spirit most and offers a highly educational and interesting experience for us,
 +
was the inhibition of a protease for washing detergents.
 +
<br/>
 +
So far, proteases in washing detergents are being inhibited by boric acid and tons of it are needed every year.
 +
Its handling in this scale is complicated and additionally, the ECHA (European Chemicals Agency) classified this chemical
 +
as a substance of very high concern. If we can make our idea work, the protease in the washing detergents would be produced
 +
inactive and could be activated with a small, inexpensive device that can be used with any normal washing machine. Thus,
 +
the amount of chemical needed could be reduced by a great deal, as only one molecule per enzyme is necessary for inhibition.
 +
That would make a difference, especially for chemical workers, who have to handle tons of boric acid, but also for every
 +
household and sewage disposal. <br/>
 +
As a side project to the development of the “uncaging” device for the washing machine,
 +
our engineers will also work on an affordable “Dark Bench” that will make sterile handling of light-sensitive chemicals,
 +
needed for our work, more easy.<br/>
 +
</p>
 +
</div>
 +
</div>
 +
<div class=" footer_area">
 +
<div class=" footer">
 +
<div class=" single_footer_container">
 +
<div class=" single_footer floatleft">
 +
 
 +
 
 +
<p><a href="http://igem.rwth-aachen.de/" style="text-decoration: none" >Link to our website</a><br/>
 +
<a href="https://2014.igem.org/Team:Aachen" style="text-decoration: none"> Wiki 2014 Aachen</a><br/>
 +
<a href="https://2015.igem.org/Team:Aachen" style="text-decoration: none" > Wiki  2015 Aachen</a><br/>
 +
<a href="#">igem@rwth-aachen.de</a></p>
 +
</div>
 +
<div class=" single_footer floatleft"></div>
 +
<div class=" single_footer ">
 +
 
 +
<a href="https://www.facebook.com/iGEMAachen"  title="facebook"><i class="fa fa-facebook-square fa-3x "></i></a>&nbsp;&nbsp;&nbsp;&nbsp;
 +
<a href="https://twitter.com/iGEMAachen"  title="twitter"><i class="fa fa-twitter-square fa-3x"></i></a>&nbsp;&nbsp;&nbsp;&nbsp;
 +
<a href="https://www.instagram.com/igem.Aachen"  title="Instgram"><i class="fa fa-instagram fa-3x"></i> </a>&nbsp;&nbsp;&nbsp;&nbsp;
 +
<a href="https://www.youtube.com/channel/UCnIsgLJVUFhwqUYJtdd2tIA?app=desktop"  title="YouTube">
 +
<i class="fa fa-youtube-square fa-3x"></i></a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 +
 
 +
</div>
 +
 
 +
 
 +
 
 +
        </div>
 +
            </div>
 +
</div>
 +
 
 +
 
 +
    <script src="Team:Aachen/jquery.min.js"></script>
 +
    <script src="Team:Aachen/custom.js"></script>
 +
    <script src="Team:Aachen/lightslider.js"></script>
 +
 
 +
<script>
 +
$(document).ready(function() {
 +
$("#content-slider").lightSlider({
 +
loop:true,
 +
keyPress:true
 +
});
 +
$('#image-gallery').lightSlider({
 +
gallery:true,
 +
item:1,
 +
thumbItem:9,
 +
slideMargin: 0,
 +
speed:500,
 +
auto:true,
 +
loop:true,
 +
onSliderLoad: function() {
 +
$('#image-gallery').removeClass('cS-hidden');
 +
}
 +
});
 +
});
 +
</script>
 +
 
 +
 
 +
</body>
 +
</html>

Revision as of 11:44, 25 August 2016

Welcome to iGEM Aachen 2016

Project Description

The following text shall inform you about what we will try to achieve this year and give you a little insight about how and why we chose the topic we will work on.
In our brainstorming phase, the initial idea that met with broad approval in the team, included reversible inhibition of an enzyme to improve a lab method. So we dived into research about enzyme inhibition and came up with several possibilities and approaches. Especially "Photocaging", a method using photoliable molecules to reversibly inactivate all kinds of compounds and reactivate them with light, really awakened interest in all of us. Along with knowledge about inhibition, more and more application possibilities occurred and gained shape as we talked to several supporters in academics as well as in industry.
In the end, the project that suits the iGEM spirit most and offers a highly educational and interesting experience for us, was the inhibition of a protease for washing detergents.
So far, proteases in washing detergents are being inhibited by boric acid and tons of it are needed every year. Its handling in this scale is complicated and additionally, the ECHA (European Chemicals Agency) classified this chemical as a substance of very high concern. If we can make our idea work, the protease in the washing detergents would be produced inactive and could be activated with a small, inexpensive device that can be used with any normal washing machine. Thus, the amount of chemical needed could be reduced by a great deal, as only one molecule per enzyme is necessary for inhibition. That would make a difference, especially for chemical workers, who have to handle tons of boric acid, but also for every household and sewage disposal.
As a side project to the development of the “uncaging” device for the washing machine, our engineers will also work on an affordable “Dark Bench” that will make sterile handling of light-sensitive chemicals, needed for our work, more easy.

Link to our website
Wiki 2014 Aachen
Wiki 2015 Aachen
igem@rwth-aachen.de