Difference between revisions of "Team:Slovenia/Basic Part"
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<p>The BioBrick nominated for best part is MscS (<a href="http://parts.igem.org/Part:BBa_K1965000">BBa_K1965000</a>) from our Mechanosensing Collection. This part | <p>The BioBrick nominated for best part is MscS (<a href="http://parts.igem.org/Part:BBa_K1965000">BBa_K1965000</a>) from our Mechanosensing Collection. This part | ||
| − | contains the coding sequence of the bacterial mechanosensitive channel of small conductance | + | contains the coding sequence of the bacterial mechanosensitive channel of small conductance (MscS). It has been previously described as an important receptor involved |
in bacterial sensing of mechanical stress. We expressed and characterized it in mammalian cells, where it served as the sensor that translates the ultrasound stimulation | in bacterial sensing of mechanical stress. We expressed and characterized it in mammalian cells, where it served as the sensor that translates the ultrasound stimulation | ||
into calcium ion influx, thereby playing a central role our design of ultrasound responsive cells as well as cells responsive to the touch (Touchpaint).</p> | into calcium ion influx, thereby playing a central role our design of ultrasound responsive cells as well as cells responsive to the touch (Touchpaint).</p> | ||
Revision as of 13:55, 18 October 2016
New Basic part
The BioBrick nominated for best part is MscS (BBa_K1965000) from our Mechanosensing Collection. This part contains the coding sequence of the bacterial mechanosensitive channel of small conductance (MscS). It has been previously described as an important receptor involved in bacterial sensing of mechanical stress. We expressed and characterized it in mammalian cells, where it served as the sensor that translates the ultrasound stimulation into calcium ion influx, thereby playing a central role our design of ultrasound responsive cells as well as cells responsive to the touch (Touchpaint).
