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Revision as of 16:36, 19 October 2016
Main Heading UI iGEM Team 2016
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Our Project: HI, Vax!
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HIV is one of the biggest health issues the world has ever faced, and although antiretroviral therapy (ART) has made it possible to prevent mortality in HIV patients, it has several limitations, including the logistic and economic burden that arises from the need for lifelong treatment. To end HIV, we still need a cure. Today, the best hope for a cure is DNA vaccines, which are DNA molecules that harbour a gene encoding an antigen. When administered, cells will take up these molecules and produce the antigen. Dendritic cells will take this antigen to lymph nodes and present them to T cells, activating them and licensing them to hunt and kill infected cells. In theory, this would allow for the elimination of viral reservoir in the body. In reality, however, DNA vaccination for HIV hasn't worked in humans.
Our Parts
