Difference between revisions of "Team:Exeter"
AndrewWild (Talk | contribs) |
|||
| Line 554: | Line 554: | ||
Biosafety is an important issue facing synthetic biology. Concerns surrounding synthetic organisms escaping into the environment has prompted the development of novel methods of bio-containment. Despite this, kill switches - inducible genetic devices that cause cell death - are poorly categorised in the standard registry of genetic parts. There is a distinct lack of quantitative data which prevents them being used with confidence.</p> | Biosafety is an important issue facing synthetic biology. Concerns surrounding synthetic organisms escaping into the environment has prompted the development of novel methods of bio-containment. Despite this, kill switches - inducible genetic devices that cause cell death - are poorly categorised in the standard registry of genetic parts. There is a distinct lack of quantitative data which prevents them being used with confidence.</p> | ||
| − | <p id="pp">Many iGEM projects that focus on bioremediation or require an organism to be released from the lab use kill switches to address concerns about the effect of GMOs on the environment. Our project seeks to investigate the effectiveness of different types of kill switch.We want to quantify their robustness after several generations and compare the stability of these devices when integrated into the genome or carried on a plasmid. We are testing three types of kill switch: a chemical kill switch using the fluorescent proteins KillerOrange and KillerRed, an enzymatic kill switch that lyses the cell on production and a DNAse kill switch that targets DNA disruption | + | <p id="pp">Many iGEM projects that focus on bioremediation or require an organism to be released from the lab use kill switches to address concerns about the effect of GMOs on the environment. Our project seeks to investigate the effectiveness of different types of kill switch.We want to quantify their robustness after several generations and compare the stability of these devices when integrated into the genome or carried on a plasmid. We are testing three types of kill switch: a chemical kill switch using the fluorescent proteins KillerOrange and KillerRed, an enzymatic kill switch that lyses the cell on production and a DNAse kill switch that targets DNA disruption. |
</p> | </p> | ||
Revision as of 09:08, 26 August 2016
