Difference between revisions of "Team:NTU-Singapore"
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<h2> Welcome to NTU-Singapore's wiki :) </h2> | <h2> Welcome to NTU-Singapore's wiki :) </h2> | ||
| − | <h3> | + | <h3>Description</h3> |
<p>The power of targeted genome editing for gene therapy is the primary inspiration for our team to study on the CRISPR-Cas9 system. With the accuracy of this CRISPR-Cas system, it can undoubtedly spur the development of molecular therapeutic for human diseases. However, as CRISPR-Cas system is still a newly developed genome editing tool, there are challenges faced by using CRISPR-Cas system. For instance, off-target mutagenesis, efficiency of Cas9 nucleases are still not well-compared among different bacterial species and the existed Cas9 nuclease might achieves only moderate efficiency for genome targeting. Hence, our team would like to firstly conduct a comprehensive study on characterization and evaluation of Cas9 nucleases from different species. Besides, research works on improving the efficiency of HDR for double stranded donor template will be performed as well.</p> | <p>The power of targeted genome editing for gene therapy is the primary inspiration for our team to study on the CRISPR-Cas9 system. With the accuracy of this CRISPR-Cas system, it can undoubtedly spur the development of molecular therapeutic for human diseases. However, as CRISPR-Cas system is still a newly developed genome editing tool, there are challenges faced by using CRISPR-Cas system. For instance, off-target mutagenesis, efficiency of Cas9 nucleases are still not well-compared among different bacterial species and the existed Cas9 nuclease might achieves only moderate efficiency for genome targeting. Hence, our team would like to firstly conduct a comprehensive study on characterization and evaluation of Cas9 nucleases from different species. Besides, research works on improving the efficiency of HDR for double stranded donor template will be performed as well.</p> | ||
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<h5> Editing your wiki </h5> | <h5> Editing your wiki </h5> | ||
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p> | <p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p> | ||
| − | <p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> | + | <p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> Click here to edit this page! </a></p> |
</div> | </div> | ||
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<h5> Uploading pictures and files </h5> | <h5> Uploading pictures and files </h5> | ||
<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br /> | <p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br /> | ||
| − | When you upload, set the "Destination Filename" to | + | When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p> |
Revision as of 18:29, 21 September 2016
Welcome to NTU-Singapore's wiki :)
Description
The power of targeted genome editing for gene therapy is the primary inspiration for our team to study on the CRISPR-Cas9 system. With the accuracy of this CRISPR-Cas system, it can undoubtedly spur the development of molecular therapeutic for human diseases. However, as CRISPR-Cas system is still a newly developed genome editing tool, there are challenges faced by using CRISPR-Cas system. For instance, off-target mutagenesis, efficiency of Cas9 nucleases are still not well-compared among different bacterial species and the existed Cas9 nuclease might achieves only moderate efficiency for genome targeting. Hence, our team would like to firstly conduct a comprehensive study on characterization and evaluation of Cas9 nucleases from different species. Besides, research works on improving the efficiency of HDR for double stranded donor template will be performed as well.
Before you start:
Please read the following pages:
Styling your wiki
You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.
While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.
Wiki template information
We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!
Editing your wiki
On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!
Tips
This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:
- State your accomplishments! Tell people what you have achieved from the start.
- Be clear about what you are doing and how you plan to do this.
- You have a global audience! Consider the different backgrounds that your users come from.
- Make sure information is easy to find; nothing should be more than 3 clicks away.
- Avoid using very small fonts and low contrast colors; information should be easy to read.
- Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2016 calendar
- Have lots of fun!
Inspiration
You can also view other team wikis for inspiration! Here are some examples:
Uploading pictures and files
You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to Team:YourOfficialTeamName/NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)
