(Edited text) |
|||
Line 297: | Line 297: | ||
<header id="top" class="header"> | <header id="top" class="header"> | ||
<div class="text-vertical-center"> | <div class="text-vertical-center"> | ||
− | <h1></br> | + | <h1></br> Fluigi</h1> |
− | <h3>iGem Special Track: Hardware</h3> | + | <h3>Boston University iGem Special Track 2016: Hardware</h3> |
<br> | <br> | ||
<a href="#about" class="btn btn-lg btn-dark">Find Out More</a> | <a href="#about" class="btn btn-lg btn-dark">Find Out More</a> | ||
Line 309: | Line 309: | ||
<div class="row"> | <div class="row"> | ||
<div class="col-lg-12 text-center"> | <div class="col-lg-12 text-center"> | ||
− | <h2>Fluigi is a specify, design, build | + | <h2>Fluigi is a tool used to specify, design, and build a microfluidic device.</h2> |
</div> | </div> | ||
Line 324: | Line 324: | ||
<div class="row text-center"> | <div class="row text-center"> | ||
<div class="col-lg-10 col-lg-offset-1"> | <div class="col-lg-10 col-lg-offset-1"> | ||
− | <h2> | + | <h2>What are Microfluidics?</h2> |
+ | |||
<hr class="small"> | <hr class="small"> | ||
<div class="row"> | <div class="row"> | ||
− | <div align=" | + | <div align="left"> |
− | <div class="service-item"> | + | <div class="service-item" > |
− | <span class="fa-stack fa-4x"> | + | <span class="fa-stack fa-4x" > |
− | <i class="fa fa-circle fa-stack-2x"></i> | + | <i class="fa fa-circle fa-stack-2x" ></i> |
<i class="fa fa-cloud fa-stack-1x text-primary"></i> | <i class="fa fa-cloud fa-stack-1x text-primary"></i> | ||
− | </span> | + | </span> |
− | + | ||
− | + | ||
</br> | </br> | ||
− | Microfluidic devices consist of valves and channels that can manipulate small volumes of liquids | + | Microfluidic devices are modular and consist of valves and channels that can manipulate small volumes of liquids. Using this, scientists can reduce reagent costs, automate experiments, and attain a high and more precise throughput with predictable fluid flow. |
</br> | </br> | ||
− | However, due to the technical agility, high cost and long build time, microfluidics are not | + | However, due to the technical agility, high cost and long build time, microfluidics are not often used. The current method of photolithography costs about $80,000, and also requires an expert. |
<br/> | <br/> | ||
Here's where Fluigi comes into use! | Here's where Fluigi comes into use! | ||
Line 359: | Line 358: | ||
<div class="col-lg-10 col-lg-offset-1"> | <div class="col-lg-10 col-lg-offset-1"> | ||
− | <h2 align="center"> Where can we use | + | <h2 align="center"> Where can we use Microfluidics? </h2> |
<br> | <br> | ||
− | - Synthetic Biology | + | - Synthetic Biology: |
<a href="http://pubs.rsc.org/en/content/articlepdf/2014/lc/c4lc00509k"> 'Lab on a Chip', 2014</a> | <a href="http://pubs.rsc.org/en/content/articlepdf/2014/lc/c4lc00509k"> 'Lab on a Chip', 2014</a> | ||
− | <br> | + | </br> |
− | - Experiments to monitor precise control of the number and concentration of input | + | - Experiments to monitor precise control of the number and concentration of input: |
<a href="http://stke.sciencemag.org/content/5/213/ra17.full"> 'Diverse Sensitivity Thresholds in Dynamic Signaling Response by Social Amoebae', 2012</a> | <a href="http://stke.sciencemag.org/content/5/213/ra17.full"> 'Diverse Sensitivity Thresholds in Dynamic Signaling Response by Social Amoebae', 2012</a> | ||
− | <br> | + | </br> |
− | - Single-cell tracking | + | - Single-cell tracking: |
<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836382"> 'Microfluidics for Synthetic Biology: From Design to Execution'</a> | <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836382"> 'Microfluidics for Synthetic Biology: From Design to Execution'</a> | ||
− | <br> | + | </br> |
− | - Microchemostat | + | - Microchemostat for environmental control: |
<a href="http://science.sciencemag.org/content/309/5731/137.full">'Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat', 2005</a> | <a href="http://science.sciencemag.org/content/309/5731/137.full">'Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat', 2005</a> | ||
<br> | <br> | ||
Line 407: | Line 406: | ||
<i class="fa fa-cloud fa-stack-1x text-primary"></i> | <i class="fa fa-cloud fa-stack-1x text-primary"></i> | ||
</span> | </span> | ||
− | < | + | <h3> |
− | + | Specify | |
− | + | </br> </br> | |
− | <p> | + | <p>Let's start by defining what the inputs and outputs are to your microfluidic chip! Are there any limitations in terms of port size, channel width? </p> |
− | <p> | + | <p>Fluigi will best place and route the control layer (valves to push/pull fluid through using pressure) and flow layer (through which fluid flows) of the microfluidic chip.</p> |
− | <p> | + | <p>iGem Work: The mapper (MM) tool. Click the button below to learn more about our MM tool. </p> |
− | <a href="#" class="btn btn-light">Learn More</a> | + | <a href="#" class="btn btn-light">Learn More </a> |
+ | |||
+ | </h3> | ||
</div> | </div> | ||
</div> | </div> | ||
Line 422: | Line 423: | ||
<i class="fa fa-compass fa-stack-1x text-primary"></i> | <i class="fa fa-compass fa-stack-1x text-primary"></i> | ||
</span> | </span> | ||
− | < | + | <h3> |
− | + | Design | |
− | + | </br> </br> | |
− | <p> | + | <p>Check and visualize your device layout using the Fluigi graphical user interface. </p> |
− | <p> This graphical user interface | + | <p> This graphical user interface also allows you to edit your design and control the fluids in the microfluidic chip. The interface has been made completely by the iGEM Team</p> |
− | <a href="#" class="btn btn-light">Learn More</a> | + | <a href="#" class="btn btn-light">Learn More </a> |
+ | </h3> | ||
</div> | </div> | ||
</div> | </div> | ||
Line 436: | Line 438: | ||
<i class="fa fa-flask fa-stack-1x text-primary"></i> | <i class="fa fa-flask fa-stack-1x text-primary"></i> | ||
</span> | </span> | ||
− | + | <h3> | |
− | + | Build | |
− | + | </br> </br> | |
− | <p>Ready to make your chip? Import our design files into a 3D Printer and CNC mill to make the chip! You can also make/change the setup using our parameterized designs.</p> | + | <p>Ready to make your chip? Import our design files into a 3D Printer and CNC mill to make the chip and the pump setup! You can also make/change the setup using our parameterized designs.</p> |
<p> The design of the setup is BU iGEM work, whilst the chip manufacturing is the work of our mentors. </P> | <p> The design of the setup is BU iGEM work, whilst the chip manufacturing is the work of our mentors. </P> | ||
<a href="#" class="btn btn-light">Learn More</a> | <a href="#" class="btn btn-light">Learn More</a> | ||
+ | </h3> | ||
</div> | </div> | ||
</div> | </div> | ||
Line 454: | Line 457: | ||
<!-- /.container --> | <!-- /.container --> | ||
</section> | </section> | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
<!-- Portfolio --> | <!-- Portfolio --> | ||
Line 471: | Line 467: | ||
<div class="row"> | <div class="row"> | ||
<div class="col-md-6"> | <div class="col-md-6"> | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
<div class="col-md-6"> | <div class="col-md-6"> | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
<div class="col-md-6"> | <div class="col-md-6"> | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
<div class="col-md-6"> | <div class="col-md-6"> | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
</div> | </div> | ||
<!-- /.row (nested) --> | <!-- /.row (nested) --> | ||
− | |||
</div> | </div> | ||
<!-- /.col-lg-10 --> | <!-- /.col-lg-10 --> | ||
Line 523: | Line 508: | ||
<a href="http://twitter.com/iGemHWBU">Twitter</a> | <a href="http://twitter.com/iGemHWBU">Twitter</a> | ||
<br/> | <br/> | ||
− | <a href="mailto:bu.igemhw2016@gmail.com">Email us | + | <a href="mailto:bu.igemhw2016@gmail.com">Email us</a> |
<br/> | <br/> | ||
<a href="http://cidarlab.org/Fluigi">About us</a> | <a href="http://cidarlab.org/Fluigi">About us</a> |
Revision as of 22:37, 26 June 2016
Fluigi is a tool used to specify, design, and build a microfluidic device.
What are Microfluidics?
Here's where Fluigi comes into use!
Where can we use Microfluidics?
- Synthetic Biology: 'Lab on a Chip', 2014 - Experiments to monitor precise control of the number and concentration of input: 'Diverse Sensitivity Thresholds in Dynamic Signaling Response by Social Amoebae', 2012 - Single-cell tracking: 'Microfluidics for Synthetic Biology: From Design to Execution' - Microchemostat for environmental control: 'Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat', 2005