Difference between revisions of "Team:NRP-UEA-Norwich"

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<h2>Project Description</h2>
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<h3 style="color:#72c9b6">The Team</h3>
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We are a group of undergraduate students from the University of East Anglia, which is renowned for its environmental awareness and climate change research. We are studying subjects that range from Biological Sciences, Biochemistry, Biomedicine, Computing Sciences, Molecular Biology and Natural Sciences. Having been selected for this year’s iGEM team, we are identifying ways to bring synthetic biology techniques to an interdisciplinary research project that is currently ongoing within our university.
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<h3 style="color:#72c9b6">The Science</h3>
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<p>NRP-UEA-Norwich</p>
Increasing fuel poverty and global climate change are driving the global demand for clean energy. Renewable sources of energy, such as sunlight, remain largely untapped due to challenges arising from the intermittent nature of the source. In a coal fire power plant or a nuclear fission reactor it is possible to control energy output in line with fluctuating demands for power. However with renewable sources, such as wind or solar power, electricity is only generated when the wind is blowing or the sun is shining. Thus, a major challenge for renewable energy sources is in converting these types of renewable energy into fuels that can be used to release the harnessed renewable energy as it is needed. The aim of our project is to use the methods of synthetic biology to prepare biological systems that will store solar energy as hydrogen due to the channelling of electrons from photovoltaic cells into bacteria via proteins termed “molecular nanowires”. In this way bacteria can then use this energy to drive the production of hydrogen, and this can be used to sustainably power vehicles or be burned to produce electricity on demand.
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<span>We're here to rock your world</span>
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<h3 style="color:#72c9b6">The Research</h3>
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‘Rock-breathing’ bacteria such as Shewanella oneidensis MR-1, are microbes that couple the generation of proton-motive force across the cytoplasmic membrane to reduction of minerals, located outside of the cell. The MtrC, MtrA and MtrB proteins come together to form the MtrCAB complex that spans the outer membrane in S. oneidensis MR-1. This complex has been shown to contain a network of iron atoms that conduct electrons between the cell and its environment, leading to them being termed “molecular nanowires”. The electrons transferred across the membrane can then be used by hydrogenase proteins that catalyse the reduction of protons (2H+) to dihydrogen (H2). The process is inefficient however and we aim to explore ways of increasing its efficiency, for example through use of alternative hydrogenases or alternate subunits. Additionally we wish to control protein expression at a genetic level in order to optimise the protein ratio for maximum cellular H2 production. Lastly we are also looking into ways of increasing the efficiency of electron recruitment to hydrogenase by experimenting with various modifications to the enzyme. The MtrCAB proteins have been the focus of several previous iGEM projects and one additional aim of our project will be to improve the utility of biobricks that are already housed within the iGEM repository.
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Ultimately, we hope to increase the yield of clean hydrogen produced from S. oneidensis MR-1 in a microbial-photovoltaic fuel cell. The development of efficient mechanisms for storing of energy produced from renewable sources will help counteract intermittency costs and aid their development and economic viability.
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<h2> Welcome to iGEM 2016! </h2>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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<strong>We’re a small team, doing many things!</strong><br/>We hope to increase the yield of clean hydrogen produced from S. oneidensis MR-1 in a  
 
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microbial-photovoltaic fuel cell. The development of efficient mechanisms for storing of energy produced from renewable sources will
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help counteract intermittency costs and aid their development and economic viability.
 
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<div id="introPlayVideoButton">Watch a short video about our daily lives</div>
<h5>Before you start: </h5>
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<p> Please read the following pages:</p>
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<li>  <a href="https://2016.igem.org/Requirements">Requirements page </a> </li>
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<li> <a href="https://2016.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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<li> <a href="https://2016.igem.org/Resources/Template_Documentation"> Template Documentation </a></li>
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<h5> Styling your wiki </h5>
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<h2>Learn About</h2>
<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
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<h5> Wiki template information </h5>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2016.igem.org/Judging/Pages_for_Awards/Instructions">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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<h5> Editing your wiki </h5>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
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<h2>Interact</h2>
  
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<h5>Tips</h5>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2016.igem.org/Calendar">iGEM 2016 calendar</a> </li>
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<li>Have lots of fun! </li>
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<h5>Inspiration</h5>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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<h5> Uploading pictures and files </h5>
 
<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
 
When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
 
 
 
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Revision as of 21:09, 17 October 2016

NRP-UEA-NORWICH iGEM


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NRP-UEA-Norwich

We're here to rock your world

We’re a small team, doing many things!
We hope to increase the yield of clean hydrogen produced from S. oneidensis MR-1 in a microbial-photovoltaic fuel cell. The development of efficient mechanisms for storing of energy produced from renewable sources will help counteract intermittency costs and aid their development and economic viability.

Watch a short video about our daily lives

Learn About

Interact

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