Difference between revisions of "Team:Sheffield/project/device"
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| − | <p>Our | + | <p> Our design process began with the idea of using microfluidics in a lab-on-a-chip device. Our work at the Insigneo Insitute for in silico medicine allowed us to test different patterns of this device and optimize desired characteristics such as mixing times and flow rates. This idea evolved into several others such as the use of freeze drying as a technique to store genetically modified bacteria in a state of dormancy. This then evolved into our final idea: a capsule-and-chamber device that met our requirements better overall. The capsule-and-chamber device takes inspiration from how glowsticks work (yes, glowsticks!) wherein you bend and twist the tube which releases the engineered E. coli into the reacting chamber. This entire capsule is then enclosed by an outer chamber which detects how strong a signal the reporter system is producing to deduce whether a bacterial infection is likely to be present. |
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Revision as of 23:37, 18 October 2016
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Our design process began with the idea of using microfluidics in a lab-on-a-chip device. Our work at the Insigneo Insitute for in silico medicine allowed us to test different patterns of this device and optimize desired characteristics such as mixing times and flow rates. This idea evolved into several others such as the use of freeze drying as a technique to store genetically modified bacteria in a state of dormancy. This then evolved into our final idea: a capsule-and-chamber device that met our requirements better overall. The capsule-and-chamber device takes inspiration from how glowsticks work (yes, glowsticks!) wherein you bend and twist the tube which releases the engineered E. coli into the reacting chamber. This entire capsule is then enclosed by an outer chamber which detects how strong a signal the reporter system is producing to deduce whether a bacterial infection is likely to be present.
