1. From senior citizens: I am curious about your project since it is closely related to the medicine production. I wonder whether your project can help with the treatment of disease?

2. Residents in Shanghai: I wonder whether genetically modified organisms can pose negative impact on human life. Although it can facilitate the food production in China, what are the consequences for people if they had this type of food for decades?

3. From children at the age of 6: I was heard that the cell was negligible, but I could not imagine how complicated is the cell mechanism under my observation of VR. It is not easy for a little cell to conduct such sophisticated process!! It is amazing!!

4. From parents: Thank you so much for inspiring our children with so fascinating tools, actually it is quite nice with vivid animation. I hope the teachers can use more active teaching tools like your VR model. If so, my children will not feel boring in his study!

5. From middle school students in Suzhou: I think your project is interesting in terms of mutagenesis and it can have a huge impact on the society. But I cannot fully understand your project, especially retrohoming of Group II intron.

From senior high in Guangya Middle school: Your popular lectures are interesting. Although we are facing university entrance examination, it is worthwhile broadening our horizons through popular topics that we are interested in. Thank you for your nice preparation.

6. From teachers in traditional Chinese university: Honestly speaking, it is so difficult for students to generate random mutation through research. But think bravely and do bravely, maybe it can be true in the future. Who knows! Your example is encouraging. We need to encourage more students to conduct research of their interest!

7. From leaders in Ministry of Education in China: I am so very happy to see your research project. I cannot imagine how much effort you had devoted in your research project. In future, China is paramount to be equipped with elites in science and technology! You guys are the future of China!

8 From United Kingdom Minister for Universities and Science: I am happy to know what you are engaged in. It is significant to explore your interesting area when you are young.  

We took the feedback from the public raised seriously and aimed to make improvement in our project as well as our future human practice activities. During the activity, we have mentioned about the mutation breeding during the development of spaceflight. Through the UV light in space, the mutation can be randomly generated. Some of the benefit mutations are applied into agriculture to solve the food problem. The random mutation is similar to our mutagenesis project. Some local citizens showed worried to the mutations that may pose negative consequences in our daily life. They tend to be afraid of the super-bacteria that will be difficult to be treated. Stimulated by this comment, we paid much attention in particular doing the experiments. After working with the bacteria, we auto-cleaved them instead of simply flowing into water tank to avoid the mutation generated. When working in the lab, harsh rules were made including always wearing gloves in the lab to avoid being infected by bacteria accidentally.

Furthermore, since they are worried about the super-bacteria, we educate the public with scientific knowledge to clear their misunderstanding. The high frequency of antibiotic resistance has currently become an enormous threat to human being. The increasing number of multi-drug resistance bacteria has made current antibiotics hard to cope with because of the abuse of antibiotics by individual and hospitals. Thus, we strongly emphasize the significance of antibiotics use in daily life properly. In our project, we desire to generate more benefit mutations through our in vivo process. To modify our project, we can identify more possible mutations that can fight against the antibiotic resistance problem.