Difference between revisions of "Team:Leiden"

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<html>
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  <title>
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   iGEM Leiden Wiki
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</title>
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  iGEM Leiden Wiki
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<meta name="viewport" content="width=device-width, initial-scale=1" />
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<meta http-equiv="X-UA-Compatible" content="IE=edge" />
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<meta charset="utf-8" />
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  <meta http-equiv="X-UA-Compatible" content="IE=edge" />
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<link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/libraries/bootstrap-3_3_6-dist/css/bootstrap_min_css?action=raw&amp;ctype=text/css" />
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  <meta charset="utf-8" />
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<link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/libraries/font-awesome-4_6_3/css/font-awesome_min_css?action=raw&amp;ctype=text/css" type="text/css" />
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  <link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/libraries/bootstrap-3_3_6-dist/css/bootstrap_min_css?action=raw&amp;ctype=text/css" />
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<script type="text/javascript" src="https://2016.igem.org/Team:Leiden/libraries/jquery-1_12_4_min_js?action=raw&amp;ctype=text/js">
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  <link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/libraries/font-awesome-4_6_3/css/font-awesome_min_css?action=raw&amp;ctype=text/css" type="text/css" />
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</script>
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  <script type="text/javascript" src="https://2016.igem.org/Team:Leiden/libraries/jquery-1_12_4_min_js?action=raw&amp;ctype=text/js">
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<script type="text/javascript" src="https://2016.igem.org/Team:Leiden/libraries/bootstrap-3_3_6-dist/js/bootstrap_min_js?action=raw&amp;ctype=text/js">
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  </script>
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</script>
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  <script type="text/javascript" src="https://2016.igem.org/Team:Leiden/libraries/bootstrap-3_3_6-dist/js/bootstrap_min_js?action=raw&amp;ctype=text/js">
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<link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/style/fonts/Montserrat_css?action=raw&amp;ctype=text/css" />
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  </script>
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<link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/style/fonts/Lato_css?action=raw&amp;ctype=text/css" />
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  <link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/style/fonts/Montserrat_css?action=raw&amp;ctype=text/css" />
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<link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/style/main_css?action=raw&amp;ctype=text/css" />
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  <link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/style/fonts/Lato_css?action=raw&amp;ctype=text/css" />
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<script type="text/javascript" src="https://2016.igem.org/Team:Leiden/scripts/smooth-scrolling_js?action=raw&amp;ctype=text/js">
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  <link rel="stylesheet" href="https://2016.igem.org/Team:Leiden/style/main_css?action=raw&amp;ctype=text/css" />
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</script>
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  <script type="text/javascript" src="https://2016.igem.org/Team:Leiden/scripts/smooth-scrolling_js?action=raw&amp;ctype=text/js">
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<style type="text/css">
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  </script>
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  #top_title, #sideMenu{
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  <style type="text/css">
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  #top_title, #sideMenu{
 
         display: none;
 
         display: none;
 
       }
 
       }
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         padding: 0;
 
         padding: 0;
 
       }
 
       }
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</style>
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  </style>
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<style>
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  </head>
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  .dropdown-content {
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<body id="myPage" data-spy="scroll" data-target=".navbar" data-offset="60">
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    display: none;
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  <div id="body-wrapper">
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    position: absolute;
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  <div id="nav-background" style="position: fixed; top: 15px;">
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background-color: #f9f9f9;
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  </div>
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    right: 0;
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  <nav class="navbar navbar-default navbar-fixed-top" style="position: fixed; top: 15px;">
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    <div class="container">
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}
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    <div class="navbar-header">
−
 
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      <a class="navbar-brand" href="https://2016.igem.org/Team:Leiden">
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.dropdown-content a {
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      <img alt="iGEM" src="https://static.igem.org/mediawiki/2016/c/c8/Team-Leiden-images-logo_iGEM_Leiden.png" width="40" style="position: relative; top: -10px;" />
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    color: black;
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    padding: 12px 16px;
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    text-decoration: none;
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    display: block;
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}
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.dropdown-content a:hover {background-color: }
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.dropdown:hover .dropdown-content {
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    display: block;
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  </style>
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</head>
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<body id="myPage" data-spy="scroll" data-target=".navbar" data-offset="60">
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<div id="body-wrapper">
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  <div id="nav-background" style="position: fixed; top: 15px;">
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  </div>
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  <nav class="navbar navbar-default navbar-fixed-top" style="position: fixed; top: 15px;">
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  <div class="container">
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    <div class="navbar-header">
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−
    <a class="navbar-brand" href="https://2016.igem.org/Team:Leiden">
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      <img alt="iGEM" src="https://static.igem.org/mediawiki/2016/c/c8/Team-Leiden-images-logo_iGEM_Leiden.png" width="40" style="position: relative; top: -10px;" />
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−
    </a>
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    <button type="button" class="navbar-toggle" data-toggle="dropdown" data-target="#myNavbar">
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      <span class="icon-bar">
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      </span>
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      <span class="icon-bar">
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      </span>
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      <span class="icon-bar">
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      </span>
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    </button>
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    <a class="navbar-brand" href="https://2016.igem.org/Team:Leiden/#">
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−
      LEIDEN
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−
    </a>
+
−
    </div>
+
−
    <ul class="nav navbar-nav navbar-right">
+
−
    <li class="dropdown">
+
−
      <a href="https://2016.igem.org/Team:Leiden">
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−
      OVERVIEW
+
 
       </a>
 
       </a>
−
       <div class="dropdown-content">
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       <button type="button" class="navbar-toggle" data-toggle="collapse" data-target="#myNavbar">
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      </div>
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      <span class="icon-bar">
−
    </li>
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      </span>
−
    <li class="dropdown">
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      <span class="icon-bar">
−
       <a href="https://2016.igem.org/Team:Leiden/description">
+
      </span>
−
       PROJECT
+
      <span class="icon-bar">
 +
      </span>
 +
      </button>
 +
       <a class="navbar-brand" href="https://2016.igem.org/Team:Leiden/#">
 +
       LEIDEN
 
       </a>
 
       </a>
−
      <div class="dropdown-content">
+
    </div>
−
      <!-- &lt;a href="#"&gt;DESCRIPTION&lt;/a&gt;
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    <div class="collapse navbar-collapse" id="myNavbar" style="position: relative; top: -5px;">
−
&lt;a href="science.html"&gt;SCIENCE&lt;/a&gt;
+
      <ul class="nav navbar-nav navbar-right">
−
&lt;/div&gt; -->
+
      <li>
−
      </div>
+
        <a href="https://2016.igem.org/Team:Leiden">
−
    </li>
+
        OVERVIEW
−
    <li class="dropdown">
+
        </a>
−
      <a href="https://2016.igem.org/Team:Leiden/events">
+
      </li>
−
      EVENTS
+
      <li>
−
      </a>
+
        <a href="https://2016.igem.org/Team:Leiden/description">
−
      <div class="dropdown-content">
+
        PROJECT
−
       <!-- &lt;a href="#"&gt;OVERVIEW&lt;/a&gt;
+
        </a>
−
&lt;a href="#"&gt;COLLABORATIONS&lt;/a&gt;
+
      </li>
−
&lt;/div&gt;
+
       <li>
−
&lt;!--&lt;li class="dropdown" &gt;
+
        <a href="https://2016.igem.org/Team:Leiden/events">
−
  &lt;a href="index.html"&gt; LABJOURNAL&lt;/a&gt;
+
        EVENTS
−
  &lt;div class="dropdown-content"&gt;
+
        </a>
−
&lt;/div&gt;
+
      </li>
−
&lt;/li&gt; -->
+
       </ul>
−
       </div>
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     </div>
−
     </li>
+
     </div>
−
     </ul>
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  </nav>
 +
  <div id="header-background">
 
   </div>
 
   </div>
−
  </nav>
+
  <div class="jumbotron text-center">
−
</div>
+
    <img src="https://static.igem.org/mediawiki/2016/2/27/Team-Leiden-images-logo-radiating.png" width="300" />
−
<div id="header-background">
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    <p style="font-size: 42px; color: white; text-align: center; font-family: Montserrat, sans-serif; font-weight: normal;">
−
</div>
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−
<div class="jumbotron text-center">
+
−
  <img src="https://static.igem.org/mediawiki/2016/2/27/Team-Leiden-images-logo-radiating.png" width="300" />
+
−
  <p style="font-size: 42px; color: white; text-align: center; font-family: Montserrat, sans-serif; font-weight: normal;">
+
−
  <i>
+
−
    E. colinizer
+
−
  </i>
+
−
  </p>
+
−
  <!-- &lt;p style='font-size: 1em; position: relative; top: -25px; margin-bottom: -15px;'&gt; Conquering Mars, one gene at a time &lt;/p&gt; -->
+
−
  <a class="smooth" href="https://2016.igem.org/Team:Leiden/#abstract">
+
−
  <i class="fa fa-angle-down fa-5x" aria-hidden="true">
+
−
  </i>
+
−
  </a>
+
−
</div>
+
−
<div id="abstract" style="margin-top: -55px;" class="container-fluid bg-grey">
+
−
  <div class="row">
+
−
  <div class="col-sm-2">
+
−
  </div>
+
−
  <div class="col-sm-8">
+
−
    <p>
+
−
    <b>
+
−
      Abstract
+
−
    </b>
+
−
    </p>
+
−
    <p>
+
−
    <b>
+
−
      In the near future, we will finally set foot on our neighbour planet Mars. The soil, however, is highly toxic, which makes agriculture problematic. Luckily, the bacteria of the Leiden iGEM team will be able to detoxify the soil and even produce oxygen out of it!
+
−
    </b>
+
−
    </p>
+
−
    <p class="text-justify">
+
−
    Almost 47 years ago, Neil Armstrong spoke his famous words: “That’s one small step for man, one giant leap for mankind”. The first man on the moon was a fact. Since then, scientist from all around the world are trying to put the first man on Mars. However, before this is even possible, an important obstacle needs to be overcome: 0.5 - 1% of all mars soil contains the, for humans, very toxic perchlorate (ClO
+
−
    <sub>
+
−
      4
+
−
    </sub>
+
−
    <sup>
+
−
      -
+
−
    </sup>
+
−
    ). This perchlorate is toxic for humans because it disrupts iodine uptake by the thyroid gland, thereby interfering with our overall metabolism. This would mean that, once humans are able to go to Mars, it isn’t even possible to survive there for long.
+
−
Luckily, we have found a solution.
+
−
Like the beginning of life on earth, bacteria can possibly be the beginning of life on Mars. By transferring eight genes to an
+
 
     <i>
 
     <i>
−
       E.coli
+
       E. colinizer
 
     </i>
 
     </i>
−
    bacterium, we will engineer a system that is capable of turning perchlorate in non-toxic chloride ions and oxygen.  This way we will not only detoxify the soil, but also produce oxygen, which is fundamental for human life.
 
−
    </p>
 
−
    <p>
 
−
    Possibly, the small step made with these bacteria, can be a great leap for mankind.
 
 
     </p>
 
     </p>
 +
    <!-- &lt;p style='font-size: 1em; position: relative; top: -25px; margin-bottom: -15px;'&gt; Conquering Mars, one gene at a time &lt;/p&gt; -->
 +
    <a class="smooth" href="https://2016.igem.org/Team:Leiden/#abstract">
 +
    <i class="fa fa-angle-down fa-5x" aria-hidden="true">
 +
    </i>
 +
    </a>
 
   </div>
 
   </div>
−
   <div class="col-sm-2">
+
   <div id="abstract" style="margin-top: -55px;" class="container-fluid bg-grey">
 +
    <div class="row">
 +
    <div class="col-sm-2">
 +
    </div>
 +
    <div class="col-sm-8">
 +
      <p>
 +
      <b>
 +
        Abstract
 +
      </b>
 +
      </p>
 +
      <p>
 +
      <b>
 +
        In the near future, we will finally set foot on our neighbour planet Mars. The soil, however, is highly toxic, which makes agriculture problematic. Luckily, the bacteria of the Leiden iGEM team will be able to detoxify the soil and even produce oxygen out of it!
 +
      </b>
 +
      </p>
 +
      <p class="text-justify">
 +
      Almost 47 years ago, Neil Armstrong spoke his famous words: “That’s one small step for man, one giant leap for mankind”. The first man on the moon was a fact. Since then, scientist from all around the world are trying to put the first man on Mars. However, before this is even possible, an important obstacle needs to be overcome: 0.5 - 1% of all mars soil contains the, for humans, very toxic perchlorate (ClO
 +
      <sub>
 +
        4
 +
      </sub>
 +
      <sup>
 +
        -
 +
      </sup>
 +
      ). This perchlorate is toxic for humans because it disrupts iodine uptake by the thyroid gland, thereby interfering with our overall metabolism. This would mean that, once humans are able to go to Mars, it isn’t even possible to survive there for long.
 +
Luckily, we have found a solution.
 +
Like the beginning of life on earth, bacteria can possibly be the beginning of life on Mars. By transferring eight genes to an
 +
      <i>
 +
        E.coli
 +
      </i>
 +
      bacterium, we will engineer a system that is capable of turning perchlorate in non-toxic chloride ions and oxygen.  This way we will not only detoxify the soil, but also produce oxygen, which is fundamental for human life.
 +
      </p>
 +
      <p>
 +
      Possibly, the small step made with these bacteria, can be a great leap for mankind.
 +
      </p>
 +
    </div>
 +
    <div class="col-sm-2">
 +
    </div>
 +
    </div>
 
   </div>
 
   </div>
 
   </div>
 
   </div>
−
</div>
+
  <div id="contact" class="container-fluid bg-white">
−
<div id="contact" class="container-fluid bg-white">
+
  <div class="row">
−
  <div class="row">
+
    <div class="col-sm-2">
−
  <div class="col-sm-2">
+
    </div>
 +
    <div class="col-sm-8">
 +
    <h3>
 +
      Contact information
 +
    </h3>
 +
    <p>
 +
      We would love to get in touch with you! You can direct any questions that you may have to
 +
      <a style="font-family: Montserrat, sans-serif; font-size: 12pt; color: rgb(51, 122, 183);" href="https://2016.igem.org/Team:Leiden/mailto:igem@science_leidenuniv_nl">
 +
      igem@science.leidenuniv.nl
 +
      </a>
 +
    </p>
 +
    </div>
 +
    <div class="col-sm-2">
 +
    </div>
 
   </div>
 
   </div>
−
  <div class="col-sm-8">
+
  </div>
−
    <h3>
+
  <div class="container-fluid text-center bg-grey">
−
    Contact information
+
  <div class="row">
−
     </h3>
+
     <div class="col-sm-12">
−
    <p>
+
     <a class="smooth" href="https://2016.igem.org/Team:Leiden/#myPage" title="To Top">
−
    We would love to get in touch with you! You can direct any questions that you may have to
+
−
     <a style="font-family: Montserrat, sans-serif; font-size: 12pt; color: rgb(51, 122, 183);" href="https://2016.igem.org/Team:Leiden/mailto:igem@science_leidenuniv_nl">
+
−
      igem@science.leidenuniv.nl
+
 
     </a>
 
     </a>
−
     </p>
+
    <a class="smooth" href="https://2016.igem.org/Team:Leiden/#myPage">
 +
      <i class="fa fa-angle-up" aria-hidden="true">
 +
      </i>
 +
    </a>
 +
     </div>
 
   </div>
 
   </div>
−
   <div class="col-sm-2">
+
   <div class="row" style="position: relative; left: -22px;">
−
  </div>
+
    <div class="col-sm-4">
−
  </div>
+
    <ul style="list-style-type: none;">
−
</div>
+
      <!-- &lt;li&gt; About &lt;/li&gt;
−
<div class="container-fluid text-center bg-grey">
+
−
  <div class="row">
+
−
  <div class="col-sm-12">
+
−
    <a class="smooth" href="https://2016.igem.org/Team:Leiden/#myPage" title="To Top">
+
−
    </a>
+
−
    <a class="smooth" href="https://2016.igem.org/Team:Leiden/#myPage">
+
−
    <i class="fa fa-angle-up" aria-hidden="true">
+
−
    </i>
+
−
    </a>
+
−
  </div>
+
−
  </div>
+
−
  <div class="row" style="position: relative; left: -22px;">
+
−
  <div class="col-sm-4">
+
−
    <ul style="list-style-type: none;">
+
−
    <!-- &lt;li&gt; About &lt;/li&gt;
+
 
               &lt;li&gt; Society &lt;/li&gt;
 
               &lt;li&gt; Society &lt;/li&gt;
 
               &lt;li&gt; Project &lt;/li&gt; -->
 
               &lt;li&gt; Project &lt;/li&gt; -->
−
     </ul>
+
    </ul>
 +
     </div>
 +
    <div class="col-sm-4">
 +
    <ul style="list-style-type: none; list-style-image: none;">
 +
      <li>
 +
      <a style="font-family: Montserrat, sans-serif; font-size: 12pt; color: rgb(51, 122, 183);" href="http://leidenuniv.nl">
 +
        Leiden University
 +
      </a>
 +
      </li>
 +
      <li>
 +
      <a style="font-family: Montserrat, sans-serif; font-size: 12pt; color: rgb(51, 122, 183);" href="http://www.airbusdefenceandspacenetherlands.nl">
 +
        Airbus Defence and Space Netherlands
 +
      </a>
 +
      </li>
 +
      <li>
 +
      <a style="font-family: Montserrat, sans-serif; font-size: 12pt; color: rgb(51, 122, 183);" href="https://2016.igem.org/Team:Leiden/Templates">
 +
        Wiki templates
 +
      </a>
 +
      </li>
 +
      <li>
 +
      <a style="font-family: Montserrat, sans-serif; font-size: 12pt; color: rgb(51, 122, 183);" href="https://www.sarstedt.com/en/home">
 +
        Sarstedt
 +
      </a>
 +
      </li>
 +
    </ul>
 +
    </div>
 +
    <div class="col-sm-4">
 +
    <ul style="list-style-type: none;">
 +
    </ul>
 +
    </div>
 +
  </div>
 +
  <div class="row">
 +
    <div class="col-sm-12">
 +
    <p style="text-align: center">
 +
      iGEM Leiden is an initiative by students from Leiden University
 +
    </p>
 +
    </div>
 
   </div>
 
   </div>
−
  <center>
 
−
    <table style="position: center;">
 
−
    <tr>
 
−
      <td style="padding: 20px;">
 
−
      <div class="img">
 
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        <a target="_blank" href="https://www.NEB.com">
 
−
        <img height="50" src="https://static.igem.org/mediawiki/2016/e/ef/Team-Leiden-images-sponsor-image00.png" />
 
−
        </a>
 
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      </div>
 
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      </td>
 
−
      <td style="padding: 20px;">
 
−
      <div class="img">
 
−
        <a target="_blank" href="http://www.airbusdefenceandspacenetherlands.nl">
 
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        <img height="50" src="https://static.igem.org/mediawiki/2016/d/d0/Team-Leiden-images-sponsor-image02.png" />
 
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        </a>
 
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      </div>
 
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      </td>
 
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      <td style="padding: 20px;">
 
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Revision as of 12:08, 22 July 2016

iGEM Leiden Wiki

E. colinizer

Abstract

In the near future, we will finally set foot on our neighbour planet Mars. The soil, however, is highly toxic, which makes agriculture problematic. Luckily, the bacteria of the Leiden iGEM team will be able to detoxify the soil and even produce oxygen out of it!

Almost 47 years ago, Neil Armstrong spoke his famous words: “That’s one small step for man, one giant leap for mankind”. The first man on the moon was a fact. Since then, scientist from all around the world are trying to put the first man on Mars. However, before this is even possible, an important obstacle needs to be overcome: 0.5 - 1% of all mars soil contains the, for humans, very toxic perchlorate (ClO 4 - ). This perchlorate is toxic for humans because it disrupts iodine uptake by the thyroid gland, thereby interfering with our overall metabolism. This would mean that, once humans are able to go to Mars, it isn’t even possible to survive there for long. Luckily, we have found a solution. Like the beginning of life on earth, bacteria can possibly be the beginning of life on Mars. By transferring eight genes to an E.coli bacterium, we will engineer a system that is capable of turning perchlorate in non-toxic chloride ions and oxygen. This way we will not only detoxify the soil, but also produce oxygen, which is fundamental for human life.

Possibly, the small step made with these bacteria, can be a great leap for mankind.

Contact information

We would love to get in touch with you! You can direct any questions that you may have to igem@science.leidenuniv.nl

iGEM Leiden is an initiative by students from Leiden University