Difference between revisions of "Team:HokkaidoU Japan"

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<p><b>Project description</b></p>
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<p>Hydrogel is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. So, we need another approach including biosynthesis.</p>
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<p>In this research, we expressed self-assembling peptides such as RADA-16 I and P<sub>11</sub>-4 in <i>Escherichia coli</i> and analyzed them by a series of experiments. <p/>
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<p>We also considered the application of hydrogel to immobilized proteins, which may enhance the stability of proteins. Immobilized proteins will be used in medicine and environmental study in the future.</p>
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<p><b><font face="Comic Sans MS"font size="6"><CENTER>Project description</CENTER></font></b></p>
  
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<p><font face="Comic Sans MS"font color="#6633cc"font size="5">H<font size="4">ydrogen is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. So, we need another approach including biosynthesis.</p>
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<p><font size="5">I<font size="4">n this research, we expressed self-assembling peptides such as <br><font size="5"font face="Century Gothic"><CENTER>RADA-16 I<font face="Comic Sans MS"font size="4"> and <font face="Century Gothic"font size="5">P<sub>11</sub>-4<font face="Comic Sans MS"font size="4"></CENTER><br> 　　　　　　　　　in <i>Escherichia coli</i> and analyzed them by a series of experiments. <p/>
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<p><font size="5">W<font size="4">e also considered the application of hydrogel to immobilized proteins, which may enhance the stability of proteins. Immobilized proteins will be used in medicine and environmental study in the future.</font></p>
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Revision as of 15:37, 11 August 2016