Team:Ionis Paris

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What is Quantifly ?

Nowadays, Volatile Organic Compounds (VOCs) are commonly found pollutants that have been proved present in a wide variety of everyday life situations. Though they are dangerous and present almost everywhere, VOCs are not efficiently detected. Usual detection devices are very unprecise or requires a very long exposure time. This is why we developed the Quantifly project: a combination of a bacterial biosensor , perfectly adapted to on-field measurements, and an innovative drone that will allow us to easily and rapidly quantify the amount of VOCs in the air. The biosensor relies on bioluminescence , a biochemical phenomenon that is commonly used in cell imaging. We are trying to develop a new application for bioluminescence that should allow us to create a biosensor of a new kind, entirely different from the existing devices. As for the drone, it will be designed to safely contain our organisms and carry them on the field, thus acting as mobile detection platform

Our brainstorming

This project started when we had the idea to find a new application to bioluminescence, other than tagging or imaging. We noticed that bioluminescence seemed underestimated in the competition, which encouraged us to find a project using it in a very innovative way.

The idea of using it in the detection of pollution came to us with the recent environment related conferences such as COP21 that took place in Paris. As a french team, we were very sensitive to this event and the issue of constantly increasing pollution levels, and decided to bring a contribution in order to fight the major flaws that actually exists in air quality measurement. We thus decided to focus on the creation of a drone transporting bacteria that would be able to detect and measure air pollution levels on field.

What are we doing ?

The iGEM IONIS team is developping its project through different axes. We are focused on two areas : the development of our prototype and the realisation of our own european jamboree, the European Experience.

Our prototype

Our R&D team is working hard to develop a complete and functional prototype. This prototype is what we can call a biological system. It is composed of :

• An engineered micro organism such as a bacteria containing our biosensor plasmid
• A drone designed to allow the hermetic transportation of our micro organism while being able to react to the air pollution

In order to lead this project to its realisation, our biology team works in pair with mechanical engineers and computer scientists to develop our product, making our project a multidisciplinary work, which is our strength and allows us to adopt a different approach to synthetic biology.

The European Experience

The iGEM IONIS team and the iGEM Evry team worked together to accomplish a great gathering of the european teams : a european jamboree ! We organized over a week end a symposium with more than 150 people that could assist to conferences and expose their projects, and create great network through the iGEM competition. We also wanted to give all european teams the opportunity to live an incredible weekend, by coming to Paris and being able to live the "science dream" in the city of light !

What we aim to do in the iGEM

Though our project aims to realise a lot in a short period of time, we have objectives that would develop further our project Quantifly :

• We wish to compare our measurement results with already existing results gathered with different methods, in order to evaluate our biosensor efficiency
• We want to optimize our bacteria by enhancing the bioluminescence signal emitted by the cell
• Also, we aim to develop metabolic pathways in order to add a degradation ability to the cell in complement of detecting and measuring pollutant levels in the air.
• Last but not least, we want to popularize even more synthetic biology by participating in other science conferences during all the year 2016.

Before you start:

Please read the following pages:

• Requirements page
• Wiki Requirements page
• Template Documentation

Wiki template information

We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!

Editing your wiki

On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!

Use WikiTools - Edit in the black menu bar to edit this page

Tips

This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started:

• State your accomplishments! Tell people what you have achieved from the start.
• Be clear about what you are doing and how you plan to do this.
• You have a global audience! Consider the different backgrounds that your users come from.
• Make sure information is easy to find; nothing should be more than 3 clicks away.
• Avoid using very small fonts and low contrast colors; information should be easy to read.
• Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the iGEM 2016 calendar
• Have lots of fun!

Inspiration

You can also view other team wikis for inspiration! Here are some examples:

• 2014 SDU Denmark
• 2014 Aalto-Helsinki
• 2014 LMU-Munich
• 2014 Michigan
• 2014 ITESM-Guadalajara
• 2014 SCU-China

Uploading pictures and files

You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to
T--YourOfficialTeamName--NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)

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