Team:Bordeaux
Abstract
Who has never suffered from sleep disorders ?
A 2008 report of INPES, a French public institute, has shown that 45% of the 25-45 year-old population think that they do not sleep enough. This lack causes a fair bit of negative impacts : focus decreasing, immune system weakening, increasing the risk of cardiovascular diseases... Even if these statistics are high, today's medecine is not efficient enough when it comes to heal people suffering from sleep disorders. A classic example would be sleeping pills for chronic insomnia. Actually, they only treat the symptoms, not the source.
iGEM Bordeaux 2016 team's subject of study is the DSIP, a sleep-inducing peptid which seems to be promising. In order to understand in which mecanisms this peptid is involved, it will be produced by the E. coli bacteria as a bio factory and then given to a nematode called C. elegans. The sleeping process of this so called nematode will be studied using a CRISPR-methylase system, which is a modified CRISPR-CAS9, with the purpose of activating or deactivating genes participating in this process.
Who are iGEM Bordeaux ?
We are 27 students from Bordeaux University and the engineering school ENSTBB.
Come here and meet us!
Sponsors
On behalf of the entire team, we would like to thank our sponsors for allowing us to build this project and present it at the 2016 edition of the Internationnal Genetically Engineered Machine competition!
How to contact us ?
Feel free to email us to provide some feedback on our project, have some informations on the team and our work, or to just say hello !
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