Team:DTU-Denmark/Safety
Safety
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Precautionary work
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To minimize the risks while working on the iGEM project we choose the chassis organism Yarrowia lipolytica which is generally regarded as safe (GRAS) and non-pathogenic to humans. Aside from that we worked with the Escherichia coli DH5 alpha laboratory strain which does not pose a threat to healthy humans. We also did some growth experiment with Saccharomyces cerevisiae, another GRAS organism.
In our choice of genetic material we considered the risks the origin organism could pose. We only used genes from safe sources such as Xanthophyllomyces dendrorhous, Renilla reinformis and the human gene for pre-insulin codon optimised with our own codon-optimization tool for Y. lipolityca.
- Choosing a non-pathogenic chassis
- Choosing parts that will not harm humans / animals / plants
- Substituting safer materials for dangerous materials in a proof-of-concept experiment
- Including an "induced lethality" or "kill-switch" device
Safe Lab Work
What safety procedures do you use every day in the lab? Did you perform any unusual experiments, or face any unusual safety issues? Write about them here!
Safe Shipment
Did you face any safety problems in sending your DNA parts to the Registry? How did you solve those problems?
Section 2
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Section 2.1
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Section 3
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Section 4
Has ut facer debitis, quo eu agam purto. In eum justo aeterno. Sea ut atqui efficiantur, mandamus deseruisse at est, erat natum cum eu. Quot numquam in vel. Salutatus euripidis moderatius qui ex, eu tempor volumus vituperatoribus has, ius ea ullum facer corrumpit.
Section 5
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