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We are team of creative photographers. We passionate with photography and other creative things. If you are looking professional photography theme with endless possibilities, you come in right place. This template consist of well-organized layers. Tons of features waiting for you.
We are team of creative photographers. We passionate with photography and other creative things. If you are looking professional photography theme with endless possibilities, you come in right place.
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We are team of creative photographers. We passionate with photography and other creative things. If you are looking professional photography theme with endless possibilities, you come in right place. This template consist of well-organized layers. Tons of features waiting for you.
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Mae West
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Controller based on Quorum Sensing System to manipulate cell-cell communication and population behaviors
What do we do in this summer?
- This summer we investigated a kind of quorum sensing molecular, AI-2(autoinducer-2). In our project we try to construct the bacteria machine called Ai-2 Controller which can produce or degrade AI-2 according to the environment and induction conditions. With the important role of AI-2 in population behavior such as biofilm formation, bioluminescence, virulence and antibiotic resistance, AI-2 Controller has its great applications in the fields of fermentation production, reducing antibiotic resistance, improve intestinal microflora environment and so on.
What are the characteristics of AI-2 Controller?
No Side Effect？
No waste to the fermentation environment
AI-2 Consumer & Supplier？
Modulate the external AI-2 environment & attenuating cell–cell communication
Biosafety？
No overgrowth in the fermentation environment & outside the lab
References
- Thompson J A, Oliveira R A, Djukovic A, et al. Manipulation of the quorum sensing signal AI-2 affects the antibiotic-treated gut microbiota[J]. Cell reports, 2015, 10(11): 1861-1871.
- Zargar A, Quan D N, Emamian M, et al. Rational design of ‘controller cells’ to manipulate protein and phenotype expression[J]. Metabolic engineering, 2015, 30: 61-68.
