Team:Paris Bettencourt/Model

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@iGEM_Paris

Modelling Group: Computationally model stain removal using enzymes

Goals

• To make a computational model to analyze stain-enzyme dynamics
• To find optimum parameters

BioBricks

• BioBrick 1
• BioBrick 2
• BioBrick 3

Results

• Developed a differential equation model to analyze stain dynamics
• A computational approach using Gillespie algorithm
• A computational approach using explicit finite difference method for three dimensional modelling

Methods

• Matlab
• ODE solvers
• Gillespie Algorithm
• Explicit Finite Difference method (FDM)

Abstract

Motivation and Background

Challenge: Modelling stain removal in a compact washing machine

A typical garment is composed of several square meters of fabric and a typical washing machine has a volme of 100 liters.

Example figure box

Results

Model1: Ode-based

Model2: Gillespie Algorithm-based

Model3: 3D modelling using FDM

Methods

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Attributions

This project was done mostly by Jake Wintermute, Mislav Acman and Mani Sai Suryateja Jammalamadaka.

References

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Assay

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Microbiology

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Enzyme

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Binding

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Indigo