Silver

HP for Silver

During the project, HP devotes to study and investigate different aspects closely related to our project including ethics, law and legislation, safety, product analysis, even summary of room for improvement by the methods of literature studying, interview, questionnaire, attending Cell Therapy Annual Meeting etc. HP also had dialogue with high school students, college students and ordinary citizens.

Ethics

This is a project about treatment, which will be used on human beings finally. The ethic issue of our project contains three parts. Firstly, after we carried out an interview with doctors and patients, we found out there were some ethic issues between researchers and patients. Secondly, we searched information of animal welfare and learnt how to construct animal models because we will test our product on mice model. At last, we had a discussion about primate experiments. More链接到伦理部分

Laws and Legislation

Laws and legislation are the vital factors of our product – MSCs preparation. During the research of clinical trials, we found that there is no MSCs drug in China although there exist about 10 MSCs drugs in the world. We thought laws and legislation are the breakthrough point. So laws of several different countries were analyzed to compare with that of China, aiming to find a proper way for development of MSCs therapy in China. More (Link to 6-4 Legislation) To know how far our project would go, we asked the secretory of Stem Cell Clinical Research Experts Committee if Conditional Approval is possible in China. More (Link to 6-2.4.3 Laws and Legislation on Stem Cell)

Safety

For general view, you can see our ‘safety page’ to have an overview of our investigation and discussion on safety. Second, there are two aspects that HP did during the project. One is the investigation of lab safety awareness of college students. More (Link to 6-9.3.1 Questionnaire Report 2 - The acknowledgment of biology safety ) the other one is to make sure our product is safe for human use, we had researched on Quality Control of MSCs. More (Link to 6-2.4.2 Safety — Stem Cell Quality control)

Product analysis

At the very beginning, we thought it was so far away for our product to bring to the market that it seemed unnecessary to do the product analysis. A turning point appeared when we got to know Academician Wu’s research on a kind of MSCs drug, which encouraged us a lot and then we made a detailed product analysis including product contrastive analysis, cost analysis and intellectual property. More (Link to 6-5 Products) Additionally, we interviewed the chairman of DAAN Gene Company to know the attitude of biological company to our product. More (Link to 6-2.5 Interview DAAN Gene Company)

Education & Sustainability

Most middle school students in China have rare chance to do biochemical experiments. All they can learn is only the theory. Students and teachers from middle school were invited attend an activity – “Have a Look at Your Genome”, which aims at sharing some basic knowledge of synthetic biology and sharing what we were doing with iGEM. More (Link to 6-9.2 Education) For benefit more high school students, we wrote a guidebook for the three experiments for high school teachers so that any high school can carry out these experiments for students. More (Link to 高中生那个手册Booklet)

MSCs therapy is one of the hot research fields in resent years. However, it is little-known by the public. We held a lecture to help medical students to have a further understanding of MSCs and made a brochure introducing to the public. More (Link to 6-9.4 “MSC with GPS”)

Room for improvement

During the whole procedure of this project, for further understanding of our project, MSCs and our target audiences, we have done a lot of Human Practices work, though it remains a pity that we have not done a great job in some aspects. This summary contains what we think we could do better during the project. More Link to 6-1.3 Room for Improvement

Team:SYSU-MEDICINE/HP/Silver