• CRAFT(Community-based Retro-synthetic Analysis Functional plaTform) is an integrated software for

  • crafting synthetic biological system from design, validation to share. CRAFT aims at constructing

  • community-level synthetic biological systems in specific environments. We are inspired by evolution theory

  • and “Design and Redesign” principle in synthetic biology, regarding customized restrictions as selection

  • pressure, and exporting protocols as standardized protocol. CRAFT can be divided into three parts, CRAFT Designer,

  • system crafting engine; CRAFT Square, a platform for user a synthetic biological communication and

  • mutual assistance; Satellite, a distributed computing plug-in. We have developed five models

  • to support CRAFT, and validated its concept and function with wet-lab experiment.