Difference between revisions of "Team:Duesseldorf/Test"

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{{Template:Duesseldorf/CSS2}}
 
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<link href="https://fonts.googleapis.com/css?family=Roboto" rel="stylesheet">
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<div class="content">
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<td style="border:none; padding: 0 20px 0 20px;"> <a href="https://2016.igem.org/Team:Duesseldorf"><img src="https://static.igem.org/mediawiki/2016/f/f3/T--Duesseldorf--logo-white.svg"></a></td>
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                  <td style="border:none; padding: 0 20px 0 20px;"> <a href="https://2016.igem.org/Team:Duesseldorf"><img src="https://static.igem.org/mediawiki/2016/f/f3/T--Duesseldorf--logo-white.svg"></a></td>
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                  <td style="border:none;">
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                    <ul>
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                        <li><a href="https://2016.igem.org/Team:Duesseldorf">Home</a></li>
 +
                        <li class="dropdown">
 +
                          <a href="#" >Project</a>
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                          <div class="dropdown-content">
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                              <ul>
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                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Description">Description</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Proof">Results</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Demonstrate">Demonstrate</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Future_Applications">Future Applications</a></li>
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                              </ul>
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                          </div>
 +
                        </li>
 +
                        <li><a href="https://2016.igem.org/Team:Duesseldorf/Collaborations">Collaborations</a></li>
 +
                        <li class="dropdown">
 +
                          <a href="#">Outreach</a>
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                          <div class="dropdown-content">
 +
                              <ul>
 +
                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Outreach">Outreach</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Outreach#HP">Education</a></li>
 +
                                <li><a href="https://2016.igem.org/Team:Duesseldorf/Outreach#IHP">Integrated Practices</a></li>
 +
                              </ul>
 +
                          </div>
 +
                        </li>
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                        <li><a href="https://2016.igem.org/Team:Duesseldorf/Hardware">Hardware</a></li>
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                        <li><a href="https://2016.igem.org/Team:Duesseldorf/Attributions">Attributions</a></li>
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                        <li><a href="https://2016.igem.org/Team:Duesseldorf/Safety">Safety</a></li>
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                        <li><a style="color: white;" href="https://2016.igem.org/Team:Duesseldorf/Team">Team</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:Duesseldorf/Parts">Parts</a></li>
 +
                        <li><a href="https://2016.igem.org/Team:Duesseldorf/Experiments">Experiments</a></li>
 +
                    </ul>
 +
                  </td>
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              </tr>
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              <tr style="border:none;">
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                  <td style="border:none;">
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                    <a href="https://twitter.com/igemhhu16" style="margin:0;padding:0;">
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                    <a href="https://www3.hhu.de/igem/" style="margin:0;padding:0;">
 +
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                    <a href="https://www.youtube.com/channel/UCg7deDCwE8bCcPsF8ELnaxw" style="margin:0;padding:0;">
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                    </a>
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                    <a href="mailto:igem@hhu.de><?xml version="1.0" ?><!DOCTYPE svg  PUBLIC '-//W3C//DTD SVG 1.1//EN'  'http://www.w3.org/Graphics/SVG/1.1/DTD/svg11.dtd'><svg  id="Layer_1" version="1.1" viewBox="0 0 512 512"  class="social"  style="width:10%; margin-top:10px;enable-background:new 0 0 76 76;" xml:space="preserve" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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                    <br>
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                    Heinrich-Heine University <br />
 +
                    Universitätsstraße 1 <br />
 +
                    40225 Düsseldorf <br />
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                    Design by Marvin van Aalst <br>
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                  </td>
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              </tr>
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            </table>
 +
        </div>
 +
        <div class="page">
 +
            <div class="paper">
 +
              <div id="Navigation" class="navigation">
 +
                  <ul class="topnav">
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf">Home</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Description">Description</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Proof">Results</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Demonstrate">Demonstrate</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Future_Applications">Future Applications</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Collaborations">Collaborations</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Outreach">Outreach</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Outreach#HP">Education</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Outreach#IHP">Integrated Practices</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Hardware">Hardware</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Attributions">Attributions</a></li>
 +
                    <li><a  href="https://2016.igem.org/Team:Duesseldorf/Safety">Safety</a></li>
 +
                    <li><a style="color: black;" href="https://2016.igem.org/Team:Duesseldorf/Team">Team</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Parts">Parts</a></li>
 +
                    <li><a href="https://2016.igem.org/Team:Duesseldorf/Experiments">Experiments</a></li>
 +
                  </ul>
 +
              </div>
 +
<!------------------------------------------ ARTICLE ---------------------------------------->
 +
<div class="article">
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<div class="attention">
 +
<h1 style="color: white;">Our Team</h1>
 
<ul>
 
<ul>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf">Home</a></li>
+
<li><a style="color:white;" href="#Gallery">Gallery</a></li>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Description">Description</a></li>
+
<li><a style="color:white;" href="#MLP">MLP Career-Day</a></li>
−
<li><a  href="https://2016.igem.org/Team:Duesseldorf/Demonstrate">Demonstrate</a></li>
+
<img src="https://static.igem.org/mediawiki/2016/c/cb/T--duesseldorf--team--lustigrichtig.jpg">
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Proof">Proof</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Collaborations">Collaborations</a></li>
+
−
<li><a style="color: white;" href="https://2016.igem.org/Team:Duesseldorf/Outreach">Outreach</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Hardware">Hardware</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Attributions">Attributions</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Safety">Safety</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Team">Team</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Parts">Parts</a></li>
+
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Experiments">Experiments</a></li>
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</ul>
 
</ul>
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</td>
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</div>
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</tr>
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<img ref="https://static.igem.org/mediawiki/2016/a/a2/T--duesseldorf--team-lustig4.jpg">
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<tr style="border:none;">
+
<h2>Welcome to Optoptosis</h2>
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<td style="border:none;">
+
<p>
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Heinrich-Heine University <br />Universitätsstraße 1 <br />40225 Düsseldorf <br />igem@hhu.de <br />facebook.com/igemhhu  <br /> Design by Marvin van Aalst
+
Our group consists of 19 motivated undergraduate students, that came together in late 2015 to found the first iGEM Team of the Heinrich Heine University in Duesseldorf.  In 2015 we made it our goal, to create a new and innovative application for synthetic biology and become a part of the renowned iGEM competition. <br>
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</td>
+
Already in the early stage of the project it was definite that we would emphasize on creating a mechanism to fight one of the deadliest diseases in the world: cancer. On this page we will tell you how we approach this big goal.
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</tr>
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</p>
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</table>
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<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
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 +
<div id="Gallery" class="gallery">
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<div class="row">
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<div class="cell-left">
 +
<div class="sg-container">
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<img src="https://static.igem.org/mediawiki/2016/thumb/2/2e/Team-opoptosis-2016-alina.jpg/450px-Team-opoptosis-2016-alina.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/d/db/Team-opoptosis-2016-alina-crazy.jpg/450px-Team-opoptosis-2016-alina-crazy.jpg" /> </div>
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</div>
 
</div>
 
</div>
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<div class="page">
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<div class="cell-right">
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<div class="paper">
+
<h2>Alina Kuklinski</h2>
−
<div id="Navigation" class="navigation">
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<ul>
−
<ul class="topnav">
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<li> <strong>Nickname</strong>: grüner Bär </li>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf">Home</a></li>
+
<li> <strong>Study Path</strong>: Biology </li>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Description">Description</a></li>
+
<li> <strong>Hobbys</strong>: table tennis, cooking, pubs, hiking, nature </li>
−
<li><a  href="https://2016.igem.org/Team:Duesseldorf/Demonstrate">Demonstrate</a></li>
+
<li> <strong>Favorite chemical</strong>: Trimethyl borate - because it is a colourless liquid that burns with a green flame. </li>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Proof">Proof</a></li>
+
<li> <strong>Favorite Pokémon</strong>: Venonat </li>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Collaborations">Collaborations</a></li>
+
<li> <strong>Favorite Beer</strong>: "Altbier" Düsseldorf's best beer </li>
−
<li><a style="color: black;" href="https://2016.igem.org/Team:Duesseldorf/Outreach">Outreach</a></li>
+
<li> <strong>Favorite Quote</strong>: “No man needs a vacation so much as the man who has just had one.” - Elbert Hubbard </li>
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<li><a href="https://2016.igem.org/Team:Duesseldorf/Hardware">Hardware</a></li>
+
</ul>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Attributions">Attributions</a></li>
+
</div>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Safety">Safety</a></li>
+
</div>
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Team">Team</a></li>
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<div class="row">
−
<li><a href="https://2016.igem.org/Team:Duesseldorf/Parts">Parts</a></li>
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<div class="cell-left">
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<li><a href="https://2016.igem.org/Team:Duesseldorf/Experiments">Experiments</a></li>
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<div class="sg-container">
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</ul>
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<img src="https://static.igem.org/mediawiki/2016/thumb/d/d8/Team-opoptosis-2016-carima.jpg/450px-Team-opoptosis-2016-carima.jpg" />
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</div>
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<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/5/57/Team-opoptosis-2016-carima-crazy.jpg/450px-Team-opoptosis-2016-carima-crazy.jpg" /> </div>
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<! ------------------------------------- ARTICLE --------------------------------------->
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</div>
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<div class="article">
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</div>
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<h1 id="Overview">Outreach overview</h1>
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<div class="cell-right">
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<b>
+
<h2>Carima Weinert</h2>
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<p>Soon after starting our project we came to the conclusion that it is of high importance to on the one hand promote our project to the public through many channels and on the other hand also to gain knowledge about certain aspects related to our project. Our promotion therefore involved a press release, which lead to numerous newspaper articles, radio interviews, a television report, several public lectures at schools and at university establishments, a postcard exchange involving a cooperation with several other German iGEM teams and a broad social media appearance. </p>
+
<ul>
−
<p>To acquire more knowledge about aspects of our project, we had talks with experts of different fields, we visited the Federal Institute for Drugs and Medical Devices, the 5th Information Day about Cancer […] and conducted a public survey.</p>
+
<li> <strong>Nickname</strong>: catlady </li>
−
<p>In more detail, parts of our outreach were… </p>
+
<li> <strong>Study Path</strong>: Biology </li>
−
</b>
+
<li> <strong>Hobbys</strong>: Food and TV shows </li>
−
                    <h3><a href="#HP">Human Practice: Education in Public</a></h3>
+
<li> <strong>Favorite Enzyme</strong>: RuBisCo </li>
 +
<li> <strong>Favorite Pokémon</strong>: Sheinux </li>
 +
<li> <strong>Favorite Beer</strong>: Veltins </li>
 +
<li> <strong>Life Motto</strong>: Driver picks the music shotgun shuts his cakehole </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/3/32/Team-opoptosis-2016-caro.jpg/450px-Team-opoptosis-2016-caro.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/2/24/Team-opoptosis-2016-caro.-razy.jpg/450px-Team-opoptosis-2016-caro.-razy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2>Carolin Krämer </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Mutti </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Cooking, baking, reading </li>
 +
<li> <strong>Favorite Chemical</strong>: Prolin </li>
 +
<li> <strong>Favorite Pokémon</strong>: Arcanine </li>
 +
<li> <strong>Favorite Beer</strong>: Koelsch </li>
 +
<li> <strong>Life Motto</strong>: Live slow. Die whenever </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/d/d8/Team-opoptosis-2016-cluadia.jpg/450px-Team-opoptosis-2016-cluadia.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/1/17/Team-opoptosis-2016-cluadia-crazy.jpg/450px-Team-opoptosis-2016-cluadia-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Claudia Kalus </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: DrosophiLORD </li>
 +
<li> <strong>Study Path</strong>: Biology, B.Sc. </li>
 +
<li> <strong>Hobbys</strong>: Drawing </li>
 +
<li> <strong>Favorite Enzyme</strong>: RubisCO </li>
 +
<li> <strong>Favorite Pokémon</strong>: Bulbasaur </li>
 +
<li> <strong>Favorite Beer</strong>: Beck's Gold </li>
 +
<li> <strong>Life Motto/Favorite Quote/Philosophy</strong>: Wer nicht phagt, der nicht gewinnt! </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/6/61/Team-opoptosis-2016-dorian.jpg/450px-Team-opoptosis-2016-dorian.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/7/7c/Team-opoptosis-2016-dorian-crazy.jpg/450px-Team-opoptosis-2016-dorian-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Dorian Röders </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Doreen </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Falconry, hunting and bouldering </li>
 +
<li> <strong>Favorite Chemical</strong>:Ethidium bromide </li>
 +
<li> <strong>Favorite Pokémon</strong>: Milotic </li>
 +
<li> <strong>Favorite Beer</strong>: I am alergic to beer :( </li>
 +
<li> <strong>Life Motto</strong>: What doesn't kill you makes you stronger or cripples you </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/8/8c/Team-opoptosis-2016-erdem.jpg/450px-Team-opoptosis-2016-erdem.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/8/86/Team-opoptosis-2016-erdem-crazy.jpg/450px-Team-opoptosis-2016-erdem-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Erdem Sunal </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Erdemeyerkolben </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Judo &amp; Basketball </li>
 +
<li> <strong>Favorite Chemical</strong>:Dinitrogen monoxide </li>
 +
<li> <strong>Favorite Pokémon</strong>: Scyther</li>
 +
<li> <strong>Favorite Beer</strong>: Ayran</li>
 +
<li> <strong>Philosophy</strong>:"Empty your mind, be formless, shapeless - like water. Now you put water into a cup, it becomes the cup. You put water into a bottle, it becomes the bottle. You put it in a teapot, it becomes the teapot. Now
 +
water can flow or it can crash. Be water my friend." -Bruce Lee
 +
</li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/a/a1/Team-opoptosis-2016-julia.jpg/450px-Team-opoptosis-2016-julia.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/e/e0/Team-opoptosis-2016-julia-crazy.jpg/450px-Team-opoptosis-2016-julia-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Julia Kapr </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Jule </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Traveling </li>
 +
<li> <strong>Favorite Chemical</strong>: ATP </li>
 +
<li> <strong>Favorite Pokémon</strong>: Vulpix </li>
 +
<li> <strong>Favorite Beer</strong>: Grevensteiner </li>
 +
<li> <strong>Life Motto</strong>: hope, believe and trust </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/1/13/Team-opoptosis-2016-julian.jpg/450px-Team-opoptosis-2016-julian.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/1/1f/Team-opoptosis-2016-julian-crazy.jpg/450px-Team-opoptosis-2016-julian-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Julian Ohl </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Jules </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Hiking, sailing </li>
 +
<li> <strong>Favorite Enzyme</strong>: BamH1 </li>
 +
<li> <strong>Favorite Pokémon</strong>: Nomplant </li>
 +
<li> <strong>Favorite Beer</strong>: Flensburger </li>
 +
<li> <strong>Philosophy</strong>: Hakuna Matata </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/9/9e/Team-opoptosis-2016-leonie.jpg/450px-Team-opoptosis-2016-leonie.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/8/8c/Team-opoptosis-2016-leonie-crazy.jpg/450px-Team-opoptosis-2016-leonie-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Leonie Wirth </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Ingo </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: To spend time with my dog, my cat, my boyfried or with yeast in the lab </li>
 +
<li> <strong>Favorite Chemical</strong>: Bradford-solution </li>
 +
<li> <strong>Favorite Pokémon</strong>: Pummeluff </li>
 +
<li> <strong>Favorite Beer</strong>: "Alsterwasser" </li>
 +
<li> <strong>Life Motto</strong>: Somebody yeast i use to grow! </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/7/7f/Team-opoptosis-2016-maja.jpg/450px-Team-opoptosis-2016-maja.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/d/d4/Team-opoptosis-2016-maja-crazy.jpg/450px-Team-opoptosis-2016-maja-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Maja Magel </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Majoe </li>
 +
<li> <strong>Study Path</strong>: Biology B.Sc. </li>
 +
<li> <strong>Hobbys</strong>: Reading, getting people to sing Disney songs (or at least give them earworms/ catchy tunes), daydreaming, museums, discussions about "god and the world" </li>
 +
<li> <strong>Favorite Gene</strong>: Dorsal gen "spätzle" in Drosophila. Because it is the same as in Spätzle (sort of pasta in Germany, typical for the Swabian region) </li>
 +
<li> <strong>Favorite Pokémon</strong>: Alakazam </li>
 +
<li> <strong>Favorite Beer</strong>: Beer, that does not smell or taste like beer. Basically, no beer </li>
 +
<li> <strong>Life Motto</strong>: Dreams get you started. Discipline keeps you going. - Jim Rohn </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/a/a2/Team-opoptosis-2016-marcel.jpg/450px-Team-opoptosis-2016-marcel.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/8/85/Team-opoptosis-2016-marcel-crazy.jpg/450px-Team-opoptosis-2016-marcel-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Marcel Dickmanns </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Mahhhcel </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Music, Basketball, Outdoors </li>
 +
<li> <strong>Favorite Chemical</strong>: Tryptophan </li>
 +
<li> <strong>Favorite Pokémon</strong>: Alakazam </li>
 +
<li> <strong>Favorite Beer</strong>: Good old german pils </li>
 +
<li> <strong>Life Motto</strong>: - </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/e/e6/Team-opoptosis-2016-martin.jpg/450px-Team-opoptosis-2016-martin.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/d/d8/Team-opoptosis-2016-martin-crazy.jpg/450px-Team-opoptosis-2016-martin-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Martin Duemmel </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Martini </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Videogames, reading, tabletop wargaming </li>
 +
<li> <strong>Favorite Enzyme</strong>: oxidosqualene cyclase </li>
 +
<li> <strong>Favorite Pokémon</strong>: Camerupt </li>
 +
<li> <strong>Favorite Beer</strong>: Kürzer Alt </li>
 +
<li> <strong>Life Motto</strong>: Live now. Make now always the most precious time. Now will never come again. </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/c/ca/Team-opoptosis-2016-hupsi.jpg/450px-Team-opoptosis-2016-hupsi.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/b/b3/Team-opoptosis-2016-hupsi-crazy.jpg/450px-Team-opoptosis-2016-hupsi-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<div class="col-8 col-m-6 text-left">
 +
<h2> Marvin Hubert </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Hupsi </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: sport, music and spend time with friends </li>
 +
<li> <strong>Favorite Chemical</strong>: Dihydrogen Monoxide </li>
 +
<li> <strong>Favorite Pokémon</strong>: Pikachu </li>
 +
<li> <strong>Favorite Beer</strong>: Veltins </li>
 +
<li> <strong>Philosophy</strong>: Utile dulci </li>
 +
</ul>
 +
</div>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/3/35/Team-opoptosis-2016-marvin.jpg/450px-Team-opoptosis-2016-marvin.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/a/af/Team-opoptosis-2016-marvin-crazy.jpg/450px-Team-opoptosis-2016-marvin-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Marvin van Aalst </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Christian </li>
 +
<li> <strong>Study Path</strong>: Quantitative biology </li>
 +
<li> <strong>Hobbys</strong>: Drumming and sports </li>
 +
<li> <strong>Favorite Enzyme</strong>: Q5-Polymerase </li>
 +
<li> <strong>Favorite Pokémon</strong>: Donkey Kong </li>
 +
<li> <strong>Favorite Beer</strong>: nonalcoholic wheat beer </li>
 +
<li> <strong>Life Motto</strong>: Noli Timore Messorum – Terry Pratchett </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/a/af/Team-opoptosis-2016-melissa.jpg/450px-Team-opoptosis-2016-melissa.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/4/42/Team-opoptosis-2016-melissa-crazy.jpg/450px-Team-opoptosis-2016-melissa-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Melissa Meschkewitz </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Schmelissa </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Dancing, making music </li>
 +
<li> <strong>Favorite Enzyme</strong>: DNA-Polymerase III </li>
 +
<li> <strong>Favorite Pokémon</strong>: Vaporeon </li>
 +
<li> <strong>Favorite Beer</strong>: Kölsch </li>
 +
<li> <strong>Life Motto</strong>: Love what you do and do what you love. </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/7/7e/Team-opoptosis-2016-rebecca.jpg/450px-Team-opoptosis-2016-rebecca.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/c/c5/Team-opoptosis-2016-rebecca-crazy.jpg/450px-Team-opoptosis-2016-rebecca-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Rebecca Wolters </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Becks </li>
 +
<li> <strong>Study Path</strong>: Biology </li>
 +
<li> <strong>Hobbys</strong>: Fitness, Cooking and Eating </li>
 +
<li> <strong>Favorite Enzyme</strong>: Chymosin </li>
 +
<li> <strong>Favorite Pokémon</strong>: I don't have one.. </li>
 +
<li> <strong>Favorite Beer</strong>: IPA (Bierprojekt 777) </li>
 +
<li> <strong>Life Motto</strong>: Be realistic, try the impossible. </li>
 +
</ul>
 +
</div>
 +
</div>
 +
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/4/4a/Team-opoptosis-2016-rene.jpg/450px-Team-opoptosis-2016-rene.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/4/44/Team-opoptosis-2016-rene-crazy.jpg/450px-Team-opoptosis-2016-rene-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<div id="Rene Inckemann" class="row top-padding">
 +
<div class="col-8 col-m-6 text-left">
 +
<h2> René Inckemann </h2>
 
<ul>
 
<ul>
−
                            <li><a href="#Postcards">The postcard campaign we started, that involves several other german teams</a> </li>
+
<li> <strong>Nickname</strong>: Tollpatsch </li>
−
                            <li> <a href="#HDU">An info booth and two lectures during the NRW day, which celebrated the anniversary of our state’s founding, where we showed simple experiments to wake people’s interest in biology.
+
<li> <strong>Study Path</strong>: Biology </li>
−
                            <li><a href="#Radio">Two radio interviews, one with our local campus radio station and one with the Deutschlandfunk, a nation-wide radio station.</a></li>
+
<li> <strong>Hobbys</strong>: playing guitar, making music, riding motorcycle </li>
−
                            <li><a href="#Bayerischer_Rundfunk">A TV report aired on three different TV stations.</a></li>
+
<li> <strong>Favorite Enzyme</strong>: PvuII </li>
−
                            <li><a href="#Schools">Several lectures at local schools in front of Senior students who focused on biology.</a></li>                   
+
<li> <strong>Favorite Pokémon</strong>: Ivysaur </li>
−
                            <li> <a href="#Science_Slam">The participation in the Heine Slam, a cross-faculty competition at the Heinrich-Heine-University, similar to poetry slam.</a></li>
+
<li> <strong>Favorite Beer</strong>: König Pilsener </li>
−
                            <li><a href="#Juelich">We learned more about actual research in Jülich</a></li>
+
<li> <strong>Favorite Quote</strong>: Only two things are infinite, the universe snd the human stupidity and I'm not sure about the former- albert einstein </li>
−
                        </ul>
+
−
                    <h3><a href="#IHP">Intergrated Human Practice</a></h3>
+
−
                        <ul>
+
−
                            <li><a href="#BfArM">A visit at the Federal Institute for Drugs and Medical Devices, including a tour through their facilities.</a></li>
+
−
                            <li> <a href="#House_of_University">A public lecture at the “Haus der Universität”, where admission-free public lectures are held on a regular basis. </a> </li>  
+
−
 
+
−
<li><a href="#Diventura">We Skyped with a true expert for otogenetics and cancer</a></li>
+
−
+
−
                            <li><a href="#Cancer_Information_Day">We attended the 5th Information Day about Cancer at the “Haus der Universität”, where we learned a lot about the progress that was made in cancer treatment therapy.</a></li>
+
−
+
−
+
−
<li> skype bea </li>
+
−
                            <li><a href="#Patient">Talking to cancer patients gave us an impressive insight into a life with and the fight against cancer. </a></li>
+
−
<li><a href="#Survey">A survey on the general acceptance for gene therapy</a></li>
+
 
</ul>
 
</ul>
−
<br />
 
−
                    <h1 id="HP"> Human Practice: Education in Public</h1>
 
−
                       
 
−
                        <h2 id="Postcards">Postcard exchange</h2>
 
−
<p>
 
−
Raising public awareness not only about our project, but also about synthetic biology in general was always of high importance for us. We thought that other German iGEM teams may share that thought, so we decided to develop a concept in order to raise public awareness and make it possible for the other teams to do so as well. But how do you do that?
 
−
</p>
 
−
<p>
 
−
The concept our team developed was rather simple yet convincing: Every participating team has to design a postcard with an interesting image which is related to their project on the front and a little information text about synthetic biology on the back; unifying the lore of synthetic biology with fascinating, eye-catching images. A batch of each team’s postcards is then exchanged between the participating teams and then distributed by them.
 
−
</p>
 
−
<p>
 
−
After we finished creating our concept, we contacted the other German iGEM teams and presented them our concept. It was received really well and seven teams (Aachen, Bielefeld, Bonn, Goettingen, Darmstadt, Hannover, Tübingen) decided to join us and design their own postcard. The postcards were exchanged and then distributed by each team at several events like the NRW day or our public lecture at the “Haus der Universität”. We hope that by combining stunning images with short texts about synthetic biology, we are able to get people interested in synthetic biology and maybe even the iGEM competition itself.
 
−
</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/2/28/T--duesseldorf--Postkarten.jpg">
 
−
              <hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
       
 
−
<h2 id="House_of_University">Public presentation about our project, iGEM and synthetic biology at the House of the University </h2>
 
−
<p>Informing people about our project and raising awareness about synthetic biology, new methods of cancer treatment and iGEM in general has always been of high importance to us.
 
−
Besides lectures at local high schools, several press publications, an info booth and a presentation at the NRW day, we also decided to hold a lecture at the “Haus der Universität”, where admission-free public lectures are held on a regular basis.
 
−
</p>
 
−
<p>The lecture on the evening of the 11th of November was visited by a lot of people, more people than we expected to come. The audience were very diverse: There were Biology-Professors, Bachelor- and Master-Students, as well as pupils and other people, who are not connected to the field of the biological sciences at all.</p>
 
−
<p>We held a one-hour long presentation about iGEM, cancer itself, our project and our team and gave an outreach overview about what we already achieved and with whom we worked together to reach our goal.</p>
 
−
<p>Our aim was to inform people who are not in touch with biological science and research itself too, so we tried to keep it simple and deliver the information in a clear and easy understandable way.
 
−
To make sure that everyone in the audience would understand every detail of the presentation, we also gave a bit of basic information about the central dogma of molecular biology (DNA → mRNA → Protein), the DNA and proteins itself and what they are made of, as well as optogenetics and its way of functioning.
 
−
</p>
 
−
<p>At the end of the talk, we received many interesting questions and intellectual approaches.
 
−
For example, someone asked us, when the therapy that we are developing could be established. We were very happy about this question, because it showed that there was a great public interest in our project.
 
−
</p>
 
−
<p>Another spectator asked us about the applications of our therapy and to which forms and stages of cancer it could be applied. Theoretically, it could be applied at any stage and to any form of cancer.
 
−
Additionally, we got asked about whether we would apply a patent on our idea. Naturally, we will not, because the iGEM competition is not about making the biggest capital out of a project, but to promote science. <br>
 
−
Many other questions were asked, the people were very interested and wanted to know much about us and our project.
 
−
</p>
 
−
<p>After the presentation, there was a buffet in the foyer of the “Haus der Universität” for everyone who came. Every member of the team prepared something delicious to eat, so we had a big and tasty amount of food to offer. We also bought mineral water, apple juice and beer.</p>
 
−
<p>While eating and drinking, we and our guests had a very pleasant time chatting and answering more questions about us and our project. </p>
 
−
<p>The feedback that we got was mostly extremely positive: Even the ones not knowing anything about biology understood our talk and enjoyed it. We found out that many of our listeners were (former) cancer patients and therefore had a very personal tie to the topic and our project.</p>
 
−
<p>All in all, the evening was a giant success! We are very happy, that we could reach so many people so efficiently while being able to bring such a cozy and relaxed atmosphere to a science-themed evening.</p>
 
−
<p>
 
−
You can watch our presentation in german on <a href="https://www.youtube.com/watch?v=Da6DHrL_5UE">YouTube</a>
 
−
</p>
 
−
 
−
<img src="https://static.igem.org/mediawiki/2016/3/35/T--duesseldorf--HDU-glasfaser.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/6/66/T--duesseldorf--HDU-essen.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/9/97/T--duesseldorf--HDU-ende.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/9/96/T--duesseldorf--HDU-chat2.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/a/ac/T--duesseldorf--HDU-chat.jpg">
 
−
 
−
                       
 
−
                <hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                       
 
−
                        <h2 id="Radio">Radio speech</h2>
 
−
<p>On July the 7th, we had a guest appearance in the university-radio. Two of us represented our project and iGEM. By answering a lot of questions from the radio host, we were able to explain our idea and what we are doing in the lab to create a new therapy against cancer.</p>
 
−
<p>With this we wanted to acquaint the listeners about synthetic biology and make clear that it can open new opportunities in therapeutic options. Another aspect was to familiarize our project „Optoptosis“.</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/a/af/T--duesseldorf--radio-alina.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/7/78/T--duesseldorf--radio-rebecca.jpg">
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
<h2 id="Bayerischer_Rundfunk">Bayerischer Rundfunk</h2>
 
−
<p>The German television station “Bayerischer Rundfunk” asked us to present our project for television. Obviously, we happily agreed and arranged a meeting. </p>
 
−
<p>Four students from our team presented some essential methods used at the laboratory and answered detailed questions about us and our project. For us, it was a bit unfamiliar but nevertheless really interesting to act in front of a camera. </p>
 
−
<p>We had a lot of fun with the television crew and are excited to see ourselves at the television show “alpha-campus Magazin” at the end of October.</p>
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
    <h2 id="Schools">School lectures</h2>
 
−
<p>To bring our project closer to the coming generations of young scientists, we held lectures at schools.We presented our project in the “Stiftisches Humanistisches Gymnasium Mönchengladbach” and in the “Math.Nat”, which is a grammar school specialized in science. </p>
 
−
<p>We tried to explain our project to students who are not extensively informed about synthetic biology. Our goal was to fight prejudices about genetically engineered organisms. We held a discussion about the benefits as well as possible risks of our project. </p>
 
−
<p>The students were very interested in future developments. A few were even looking forward to participating in their own iGEM project when going to university and asked if they might be mentored by us.</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/2/2d/T--duesseldorf--Vortrag-dorian.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/2/23/T--duesseldorf--Vortrag-sarah.jpg">
 
−
          <hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                    <h2 id="Science_Slam">Participation in a Science-Slam</h2>
 
−
<p>As the first iGEM-Team of Düsseldorf, we participated in the „Heine Slam“, which is held yearly at the Heinrich-Heine-University. Every year, students from all faculties of the university compete with each other.</p>
 
−
<p>As soon as we heard about it, we knew it would be a great chance to promote our project even across the borders of the Faculty of Mathematics and Natural Sciences, so we signed up and were very enthusiastic about it.</p>
 
−
<p>Soon, we came together at a sunny summer day to discuss and develop ideas for our presentation. After a short time, a great idea came up: To make our presentation Pokémon-themed! Almost everyone at least heard of Pokémon’s mascot Pikachu once in their lives. We felt, that through this, we could achieve the attention and awareness of even more people.</p>
 
−
<p>In a very short amount of time, we collected many ideas and developed a presentation in the style of a Pokémon fight; we even re-wrote the lyrics of the original Pokémon theme song to fit our project.
 
−
Soon, the details were improved and we visualized the fight between „Optoptosis“ and the „Tumor“ in the classic, oldschool manner as one knows it back from the times of the GameBoy.
 
−
</p>
 
−
<p>Then the evening of the Science Slam came, many people came to the show and voted for us, so we reached the fourth place in the competition.</p>
 
−
<p>Even if we did not reach the first place, we had the feeling that we could introduce our vision and project, as well as the iGEM competition itself to many people in an entertaining way.
 
−
We are sure that we left a lasting impression.
 
−
</p>
 
−
<p>
 
−
You can see the talk on <a href="https://www.youtube.com/watch?v=lnESiO1Wdtk">YouTube</a>
 
−
</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/4/4d/T--duesseldorf--science-slam.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/8/83/T--duesseldorf--tPOKEMON.PNG">
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                    <h2 id="Juelich">Jülich Biotechday</h2>
 
−
<p>
 
−
On the 30th of September, the “Forschungszentrum Jülich” hosted the “Jülich Biotechday 2016”. Four of our members attended this event.
 
−
</p>
 
−
<p>
 
−
We visited many interesting presentations, some of the speeches in the lecture hall were about the „Development of platform technologies which facilitate construction of microbial cell factories for production of biofuels and chemicals“, “Industrial strain improvement for boosting food functionality“ or even “The plant microbiome: ecology and functioning and how plants can benefit“.
 
−
</p>
 
−
<p>
 
−
It was a nice and interesting event because we got to know the current state of research. Plus, we had a discussion with Prof. Dr. Akihiko Kondo from the university of Kobe about iGEM. Among other things, he told us about some new interesting features of the crispr-cas9 system.
 
−
</p>
 
−
<p>
 
−
During lunch break we established contacts with company representatives and got valuable information about some of the newest products.
 
−
</p>
 
−
<p>
 
−
We are looking forward to attending the next Biotechday in 2017, as well as the 40th anniversary of the Forschungszentrum Jülich.
 
−
</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/6/6a/T--duesseldorf--juelich.jpg">
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                       
 
−
            <h1 id="IHP">Integrated Human Practice</h1>                           
 
−
                <h2 id="BfArM">
 
−
Getting a knowledge injection</h1>
 
−
<p>
 
−
While building our constructs, we thought about taking our project a step further meaning to develop and establish a new therapy method using our gene constructs. For this, we took into account on how to <a href=”________”>get our construct into the relevant cells </a> and <a href=”__________”>light to the targeted tumor cells </a>. Those questions were fundamental for the future application and implementation in humans.
 
−
</p>
 
−
<p>
 
−
But there are way more steps to consider before being able to get an admission for a therapy and actually applying it in clinical practice. There are several federal agencies which control the admission of medicaments such as the <a href=”http://www.bfarm.de/EN/Home/home_node.html”>Federal Institute for Drugs and Medical Devices located in Bonn </a>, Germany and the <a href=”http://www.pei.de/EN/home/node.html”>Paul- Ehrlich- Institute in Langen </a>, Germany. Their job is to control the active substances as well as all other components of the therapy regarding certain keypoints of the guideline of The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use.
 
−
</p>
 
−
<p>
 
−
Some of the most important points a medicament has to fulfill are efficacy, safety, quality and multiefficency. Furthermore they  the federal agencies act as scientific advisors in the process of a medicament’s development. We contacted them both and luckily we were allowed to visit the Institute for Drugs and Medical Devices and also had a phone meeting with experts of the Paul- Ehrlich- Institute. They gave us a lot of input which we were able to integrate into our project.
 
−
</p>
 
−
<p>
 
−
It takes about ten to fifteen years to develop a medicament and only one out of 10000 substances finally makes it to the market. Before being allowed to test the active substance it has to undergo certain analysis such as testing for carcinogenicity, single dose as well as repeated dose toxicity, toxicokinetics, genotoxicity, reproductive toxicity, local tolerance and tests in juvenile animals. This preclinical phase lasts about four to six years and includes the previously described and standardized tests as well as animal testing.  But even if the medicament makes it to the next phase, the non- clinical phase still goes on and different analysis are made.
 
−
</p>
 
−
<p>
 
−
After this stage either the Federal Institute for Drugs and Medical Devices or the Paul- Ehrlich Institute decides whether the medicament fulfills all necessary criteria to get an admission for clinical studies. Furthermore there are different committees which decide whether clinical studies are authorized, for example the ethical committee at the Heinrich- Heine- University, Duesseldorf.
 
−
</p>
 
−
<p>
 
−
The clinical phase itself consists of three different sub- phases. First the medicament is tested within a group of about 20 healthy patients who have to be volunteers. To enlighten them and keep them informed is one major task. It is very important that they know that they are able and allowed to quit the study anytime.
 
−
</p>
 
−
<p>
 
−
Some medicaments skip this phase as it would be inconsiderate to treat healthy human beings with chemotherapy or other active substances which are toxic. Imagining that our project would successfully make it out of the preclinical phase we would not apply our therapy on healthy patients as there is no malignant tissue which would be irradiated.
 
−
</p>
 
−
<p>
 
−
The second step of the clinical phase would be within a group of about 200 sick patients. This is the so called therapeutic- exploratory stage which aims at detecting possible side effects and testing the actual efficacy. Additionally it has to be shown that this medicament actually is an improvement regarding other already existing medicaments. This part can be a controlled study meaning that there is a control group which is given a placebo and compared to the other group.
 
−
</p>
 
−
<p>
 
−
If this stage is completed successfully the third clinical phase is ready to start. Its goals are basically the same as the ones in the second clinical phase but with a higher amount of patients which is about 1000. If all criteria, quality, efficacy and safety, are fulfilled, the medicament gets approved and it can be used as a regular therapy.
 
−
</p>
 
−
<p>
 
−
After it is available on the market, the fourth stage is the pharmacovigilance which means that side effects still have to be reported because some side effects are statistically so rare that they cannot be detected in studies with 10000 patients.
 
−
</p>
 
−
<p>
 
−
Throughout all the different steps, “good clinical praxis” which is very essential, is watched by different institutions. This means that everything has to be documented properly and fulfill the required criteria.
 
−
</p>
 
−
<p>
 
−
The Paul- Ehrlich- Institute is a federal institution which promotes quality, efficacy and safety of biomedical drugs through research as well as examination and is responsible for so called advanced therapy medicinal products (ATMP). These ATMPs are defined as biomedical drugs which heal or prevent diseases by correcting, influencing or restoring physiological functions mainly through a pharmacological, immunological or metabolic effect.
 
−
</p>
 
−
<p>
 
−
ATMPs are divided into somatic cell therapeutics, biotechnological processed tissue products and, relevant to us, gene therapeutics and are subjected to special regulation. Therefore the process of getting a legal authorization is different regarding certain aspects. For example the toxicity tests are not as standardized for ATMPs because there is a higher variation and they might be more unique, so these test may not fit the active substances. In addition the amount of patients may vary as some diseases are rare and the studies are often oriented at the medical need.
 
−
</p>
 
−
<p>
 
−
Gene therapeutics are defined as medicaments which contain an active substance which consists or is made out of a recombinant nucleic acid and is used within or is given to human beings to regulate, repair, add, delete or replace nucleic acid sequences. Its therapeutic, prophylactic or diagnostic effect also has to stand in direct connection to the recombinant nucleic acid.
 
−
</p>
 
−
<p>
 
−
Before and after the production permit is given the therapeutic substance has to be developed under the so called Good Manufacturing Production- requirements of the European Medical Agency (EMA) which consists of different formal criteria. These are not only based on the final product but also on the way of production. Once the production permit is granted by the EMA for gene therapeutics, the therapeutic substance is allowed in every country within the European Union.
 
−
</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/5/5f/T--duesseldorf--bfarm-alle.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/5/53/T--duesseldorf--bfarm-sitzen.jpg">     
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                    <h2 id="HDU">HDU presentation at the NRW-Day </h2>
 
−
<p>On Saturday the 27th and Sunday the 28th of August we presented iGEM and our scientific project aiming to fight cancer at the „Haus der Universität“ at the “Schadow-Platz” in Düsseldorf. </p>
 
−
<p>This was due to the whole weekend of the „NRW-Day 2016“ being a celebration of North Rhine- Westphalia’s 70th anniversary of its capital city Düsseldorf. It was well visited and successful at the same time.</p>
 
−
<p>On the first day we managed to convince a lot of people on the streets to listen to our presentation. We held our presentation in front of a very interested and attentive audience.
 
−
Our special guests were the Minister of science Svenja Schulze and the Minister of education Sylvia Löhrmann.
 
−
</p>
 
−
<p>Furthermore, we were able to determine that there is a big necessity to educate the public about synthetic biology by having profound discussions after our talk. To our surprise, some (former) cancer patients visited us during the weekend after having heard from our project through local newspapers. </p>
 
−
<p>For the younger generation, we prepared a little experiment in the hallway. The experiment consisted of isolating DNA from pepper by using everyday utensils. Our key task in those two days was to explain the concept of the synthetic biology in a simple and intelligible way to the general public. </p>
 
−
<p>Fortunately, we succeeded due to the audience being very interested in what we are doing. Some kids were so fascinated, that they visited us another time the next day.</p>
 
−
<p>For the second day we invited other iGEM-Teams from North Rhine-Westphalia to present their projects on an hourly basis. We are very happy that every North Rhine-Westphalian team - Aachen, Bielefeld and Bonn - managed to come. The presentations were very interesting and the visitors asked for more details afterwards. All in all, the weekend was a full success.</p>
 
−
<p>We had very interesting conversations with the visitors, sparked interest in the younger generation and were able to exchange ideas with the other iGEM-teams.</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/8/86/T--duesseldorf--NRW-erklaeren.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/a/ae/T--duesseldorf--NRW-Vortrag2.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/5/58/T--duesseldorf--NRW-Vortrag.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/a/a0/T--duesseldorf--NRW-Versuch.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/9/95/T--duesseldorf--NRW-Team.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/e/e4/T--duesseldorf--NRW-DNA.jpg">
 
−
<img src="https://static.igem.org/mediawiki/2016/7/77/T--duesseldorf--HDU_Poster.jpg">
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                    <h2 id="Diventura">Seeking expertise from Barbara Diventura (former DKFZ)</h2>
 
−
<p>
 
−
On Tuesday, the 20th of September, we had the great opportunity to discuss our project with Dr. Barbara Diventura and seek her professional opinion.
 
−
</p>
 
−
<p>
 
−
Barbara Diventura is an expert in the fields of cell biology and cancer research, her work focuses on signaling pathways and gene regulation, currently exploring the optogenetic control of nuclear protein export. Her team uses LOV, which is  one of our main optogenetic proteins. She is the head of Molecular and Cellular Engineering group at BioQuant, Heidelberg and formerly worked for DKFZ (Deutsches Krebsforschungszentrum)
 
−
</p>
 
−
<p>
 
−
During our Skype meeting we presented our project in detail. The following discussion focused especially on our two-light-component and all of the activation processes we had and still have to consider before implementing the genes in humans to expressing the proteins. <br>
 
−
Additionally, we talked about the reachability of light through cells as well as the safety aspects of viral gene transfer. In the process of our discussion, Barbara asked many helpful as well as challenging questions, thus helping us in further developing and shaping our concept.
 
−
</p>
 
−
<p>
 
−
Coming to a conclusion of our conversation, we spent the last minutes talking about the future of synthetic biology in cancer research. She told us that recognizing cancer cells from the inside of them using mRNA is a promising field of research.
 
−
</p>
 
−
<p>
 
−
All in all, talking to Barbara helped us immensely with rounding up our project and we carefully implemented her input. We are very thankful to her for taking time for us.
 
−
                        </p>
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                    <h2 id="Cancer_Information_Day">Cancer Information Day</h2>
 
−
<p>On September the 10th, we visited the 5th information day about cancer in Düsseldorf at the “Haus der Universität”. The annual organizer is the tumor center from the university hospital Düsseldorf. </p>
 
−
<p>Some physicians from the tumor center presented different topics about current research, modern potential treatments and after treatments. <br>
 
−
We were very interested in the speech by Prof. Dr. Wilfried Budach, director of the radiotherapy and radiooncology clinic at the university hospital Düsseldorf, about the significant progress in radiotherapy.
 
−
</p>
 
−
<p>He said: “We can really see a substantial improvement for patients treated with radiotherapy. This concerns the optimal dose distribution, tolerance, duration and effectiveness of the exposure.
 
−
The limits of what is physically possible are exhausted by the “Volumetric Modulated Radiotherapy” with which we have had good experiences. This therapy spares healthy tissue despite using the maximum dose. Furthermore, a worldwide study shows that the time of exposure can be reduced without the loss of efficiency for some diagnoses (e.g. breast cancer: exposure for four instead six weeks).
 
−
</p>
 
−
<p>However, the most promising insight is the combination therapy between radiotherapy and immune-checkpoint-blockers, which is already applied in the case of black skin cancer."</p>
 
−
<p>That said, there is only experimental data that have yet to be confirmed by clinical studies. However, Prof. Dr. Wilfried Budach sees huge potential for this therapy, particularly for types of cancer that were difficult to treat before.</p>
 
−
<p>We had a very interesting afternoon and are looking forward to the next information day about cancer in 2017.</p>
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
                    <h2 id="Patient">Talking to affected people</h2>
 
−
                        <p>
 
−
                            To our surprise, some (former) cancer patients visited us during the weekend of NRW-Day Celebration after having heard from our project through local newspapers. It was very interesting to hear about the experiences of a cancer patient from a personal point of view.
 
−
                        </p>
 
−
                        <p>
 
−
                            Two women who came to our presentation told us about their experiences with the diagnosis “breast cancer” and how they dealt with it. While speaking with them we noticed how much they were interested in the disease and that they were very excited about new ways to fight cancer and our project in general.
 
−
                        </p>
 
−
                        <p>
 
−
                            It was very sad to hear that one of the women felt neglected of her physicians and that they did not want to explain the working mechanisms of her medication. But this showed us very well how important it is to educate people about and clarify how the development of new therapies and medication actually works.
 
−
                        </p>
 
−
                        <p>
 
−
                            People do want to know more about this dreadful disease. In this case, it was on us to explain and how cancer is working and how we will be able to fight it in future. The next day, we continued our research even more eagerly.
 
−
                        </p>
 
−
<hr style="border:solid #0C9476 1px;margin:auto; margin-top:10px;margin-bottom:10px;">
 
−
 
−
<h2 id="Survey">Evaluation of our public survey on cancer, cancer therapy and gene therapy</h2>
 
−
<h3Participants</h3>
 
−
<p>
 
−
Our survey was conducted both, online and offline and reached a total of <b>308</b> people. <b>100</b> people completed our survey online, <b>208</b> people did it offline. Besides answering questions about cancer and gene therapy, the participants were also asked to state their gender, age and educational status. Out of our 308 participants, <b>146</b> (47%) were female, <b>99</b> (32%) male and <b>63</b> (21%) either did not want to state their gender or did not identify as male or female.
 
−
</p>
 
−
<p>
 
−
The majority of the participants, <b>284</b> (82%), were 18-29 years old. <b>4</b> (1%) were younger than 18, <b>5</b> (1%) were 30-45 years old, <b>9</b> (3%) were 46-55 years old, <b>5</b> (1%) were 56-65 years old and <b>6</b> (2%) were older than 65. <b>35</b> (10%) did not state their age.
 
−
</p>
 
−
<p>
 
−
Most of our participants were well-educated (86%), as <b>232</b> (72%) of them had a high-school diploma and <b>42</b> (14%) a university degree. <b>8</b> (3%) had a lower secondary education and <b>20</b> (6%) had a secondary school leaving certificate. <b>5</b> (2%) did not state their educational status.
 
−
</p>
 
−
<h3>Cancer and cancer therapies</h3>
 
−
<p>
 
−
It was of great interest for us to find out how well the public was educated about the almost omnipresent topic cancer. It turns out that most participants, <b>134</b> (44%), have a mediocre knowledge about cancer. About one third, <b>70</b> (23%), has a good knowledge and <b>26</b> (8%) have a very good knowledge. Therefore we can conclude that three fourth of the people have at least a basic knowledge about cancer. Only <b>67</b> (22%) of our participants stated that they have little and only <b>11</b> (4%) have no knowledge about cancer.
 
−
</p>
 
−
<p>
 
−
To get more detailed, we also wanted to know which therapy methods against cancer our participants knew. The results were quite good.
 
−
</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/8/85/T--duesseldorf--Diagramm_cancer_therapies.jpg">
 
−
<p>
 
−
The most common therapy methods, chemotherapy, radiation therapy and surgical therapy, were known to the majority of our participants. We found it to be astonishing that pretty much everyone knew about chemotherapy. Even a less common therapy, the antibody therapy was known by over a third of the participants. It was also great to see that practically everyone knew at least one therapy method. We can conclude that most participants have a basic knowledge about cancer itself and are firm with the conventional cancer therapies, yet mostly lack knowledge about more progressive methods.
 
−
</p>
 
−
<p>
 
−
Our last question about cancer, which was not included in the online survey due to the web client’s limitations, was how important the development of new therapies against cancer is for our participants. The results pretty much met our expectations, as the majority, <b>150</b> (72%) participants, think that it is of very high importance to develop new therapies and another <b>29</b> (14%) give it a high importance.
 
−
</p>
 
−
<h3>Gene therapy</h3>
 
−
<p>
 
−
The third part of our survey dealt with the topic gene therapy, a rather controversial topic, yet a crucial part of our project, as it uses certain aspects of gene therapy. Similar to the cancer part, we first wanted to know how well our participants’ knowledge is about gene therapy. It turned out that <b>96</b> (31%) participants had no knowledge at all about gene therapy and another <b>90</b> (29%) only very little. <b>63</b> (20%) said they have some knowledge, only <b>32</b> (10%) have good and <b>27</b> (9%) have very good knowledge about gene therapy. Those results were not surprising to us, as gene therapy is a rather new therapy concept, compared to i.e. chemotherapy and only rarely used.
 
−
</p>
 
−
<p>
 
−
Afterwards, we gave our participants a short text about gene therapy to give them at least some basic information, so they could answer the following questions easier.
 
−
</p>
 
−
<p>
 
−
Building on that, we wanted to know from what sources our participants would obtain information about both, cancer and gene therapy.
 
−
</p>
 
−
<img src="https://static.igem.org/mediawiki/2016/b/bd/T--duesseldorf--Diagramm_sources_information.jpg">
 
−
<p>
 
−
It turns out that, as in most other everyday situations, the internet is the primary source of information, followed by public lectures held at i.e. university facilities. Almost half of the participants would also consider consulting their physician, a third would visit a hospital.
 
−
</p>
 
−
<p>
 
−
What we were also interested in was the participants’ attitude towards gene therapy itself, as it is a highly controversial topic and often connected with things like designer babies, rather than focusing on the actual therapeutical application that is possible today. Hence we were surprised to find out that most (<b>127</b>, 41%) participants have a rather positive attitude towards gene therapy, followed by <b>107</b> (35%) participants having a neutral attitude. <b>59</b> (19%) participants even showed a very positive attitude and only 5% had a negative to very negative attitude.
 
−
</p>
 
−
<p>
 
−
Regarding cancer, we also wanted to know if our participants would prefer gene therapy over conventional cancer therapies, like the side-effect ridden chemotherapy. <b>150</b> (49%) of our participants stated that they would neither prefer nor reject gene therapy. <b>112</b> (36%) participants even would prefer gene therapy over conventional therapies. When asked if they would let gene therapy be applied on themselves, the results were similar. <b>61</b> (20%) participants think it would be very likely that they would let gene therapy be applied on them, <b>125</b> (41%) think it is likely, <b>100</b> (32%) think it may be a possibility, less than 10% think that it is unlikely to very unlikely.
 
−
</p>
 
−
<h2>Cross referencing between educational level and level of knowledge of gene therapy</h2>
 
−
<p>
 
−
We wanted to know how far the educational level is linked to the knowledge about gene therapy. While the knowledge about cancer stays constant throughout all educational levels, gene therapy shows some variations. The best educated about gene therapy are participants with a university degree, while participants with a lower secondary education or a secondary school leaving certificate had mostly no knowledge at all. University-degree holders also show the highest acceptancy for gene therapy.
 
−
</p>
 
−
<h3>Conclusion</h3>
 
−
<p>
 
−
After evaluating the survey, we can say the following things: Most people throughout all educational levels have at least a basic level of knowledge about cancer, yet most do not know a lot about gene therapy or newer cancer therapies in general. Still, the majority thinks that it is of high importance to develop new, more progressive cancer therapies, like we do. Surprisingly, the acceptance for gene therapy in general was higher than we expected, showing that people are seemingly more open for newer methods.
 
−
</p>
 
−
<h3>Tables</h3>
 
−
<p>
 
−
<table>
 
−
<tr>
 
−
<td><b>n questioned</b></td>
 
−
<td>308</td>
 
−
<td>100%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>1. Gender</b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>male</td>
 
−
<td>99</td>
 
−
<td>32%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>female</td>
 
−
<td>146</td>
 
−
<td>47%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>not specified</td>
 
−
<td>63</td>
 
−
<td>20%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>2. age</b></td>
 
−
</tr>
 
−
<tr>
 
−
<td><18</td>
 
−
<td>4</td>
 
−
<td>1%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>18-29</td>
 
−
<td>284</td>
 
−
<td>82%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>30-45</td>
 
−
<td>5</td>
 
−
<td>1%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>46-55</td>
 
−
<td>9</td>
 
−
<td>3%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>56-65</td>
 
−
<td>5</td>
 
−
<td>1%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>>65</td>
 
−
<td>6</td>
 
−
<td>2</td>
 
−
</tr>
 
−
<tr>
 
−
<td>not specified</td>
 
−
<td>35</td>
 
−
<td>10%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>3. educational status</b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>no degree</td>
 
−
<td>0</td>
 
−
<td>0%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>Lower secondary education</td>
 
−
<td>8</td>
 
−
<td>3%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>secondary school leaving certificate</td>
 
−
<td>20</td>
 
−
<td>6%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>High-school diploma</td>
 
−
<td>232</td>
 
−
<td>75%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>university degree</td>
 
−
<td>42</td>
 
−
<td>14%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>not specified</td>
 
−
<td>5</td>
 
−
<td>2%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>4. level of knowledge: cancer (1: very high - 5: none) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>1</td>
 
−
<td>26</td>
 
−
<td>8%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>2</td>
 
−
<td>70</td>
 
−
<td>23%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>3</td>
 
−
<td>134</td>
 
−
<td>44%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>4</td>
 
−
<td>67</td>
 
−
<td>22%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>5</td>
 
−
<td>11</td>
 
−
<td>4%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>5. importance of developing new cancer therapies (1: very high - 5: none) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>1</td>
 
−
<td>150</td>
 
−
<td>72%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>2</td>
 
−
<td>29</td>
 
−
<td>14%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>3</td>
 
−
<td>5</td>
 
−
<td>2%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>4</td>
 
−
<td>13</td>
 
−
<td>6%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>5</td>
 
−
<td>11</td>
 
−
<td>5%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>6. Which cancer therapy methods do you knwo? (multiple answers possible) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>Chemotherapy</td>
 
−
<td>308</td>
 
−
<td>100%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>Radiation therapy</td>
 
−
<td>257</td>
 
−
<td>83%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>Antibody therapy</td>
 
−
<td>118</td>
 
−
<td>38%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>Surgical therapy</td>
 
−
<td>217</td>
 
−
<td>70%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>Prodrug therapy</td>
 
−
<td>17</td>
 
−
<td>6%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>Viral therapy</td>
 
−
<td>60</td>
 
−
<td>19%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>None</td>
 
−
<td>2</td>
 
−
<td>1%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>7. level of knowledge: gene therapy (1: very high - 5: none) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>1</td>
 
−
<td>27</td>
 
−
<td>9%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>2</td>
 
−
<td>32</td>
 
−
<td>10%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>3</td>
 
−
<td>63</td>
 
−
<td>20%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>4</td>
 
−
<td>90</td>
 
−
<td>29%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>5</td>
 
−
<td>96</td>
 
−
<td>31%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>8. Where would you gather information about gene/cancer therapy? (multiple answers possible) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>physician</td>
 
−
<td>143</td>
 
−
<td>46%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>internet</td>
 
−
<td>254</td>
 
−
<td>82%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>relatives</td>
 
−
<td>88</td>
 
−
<td>29%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>hospital</td>
 
−
<td>98</td>
 
−
<td>32%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>lectures</td>
 
−
<td>158</td>
 
−
<td>51%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>9. Would you prefer gene therapy over conventional therapies? (1: very likely - 5: very unlikely) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>1</td>
 
−
<td>25</td>
 
−
<td>8%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>2</td>
 
−
<td>112</td>
 
−
<td>36%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>3</td>
 
−
<td>150</td>
 
−
<td>49%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>4</td>
 
−
<td>15</td>
 
−
<td>5%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>5</td>
 
−
<td>6</td>
 
−
<td>2%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>10. Attitude towards gene therapy (1: very positive - 5: very negative) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>1</td>
 
−
<td>59</td>
 
−
<td>19%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>2</td>
 
−
<td>127</td>
 
−
<td>41%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>3</td>
 
−
<td>107</td>
 
−
<td>35%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>4</td>
 
−
<td>10</td>
 
−
<td>3%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>5</td>
 
−
<td>5</td>
 
−
<td>2%</td>
 
−
</tr>
 
−
<tr>
 
−
<td colspan="3"><b>11. Personal application of gene therapy (1: much likely - 5: highly unlikely) </b></td>
 
−
</tr>
 
−
<tr>
 
−
<td>1</td>
 
−
<td>61</td>
 
−
<td>20%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>2</td>
 
−
<td>125</td>
 
−
<td>41%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>3</td>
 
−
<td>100</td>
 
−
<td>32%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>4</td>
 
−
<td>14</td>
 
−
<td>5%</td>
 
−
</tr>
 
−
<tr>
 
−
<td>5</td>
 
−
<td>8</td>
 
−
<td>3%</td>
 
−
</tr>
 
−
</table>
 
−
</p>
 
−
<!--------------------------------------- ARTICLE END -------------------------------->
 
 
</div>
 
</div>
 
</div>
 
</div>
 
</div>
 
</div>
 
</div>
 
</div>
−
</body>
+
<div class="row">
 +
<div class="cell-left">
 +
<div class="sg-container">
 +
<img src="https://static.igem.org/mediawiki/2016/thumb/6/64/Team-opoptosis-2016-tim.jpg/450px-Team-opoptosis-2016-tim.jpg" />
 +
<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/5/5a/Team-opoptosis-2016-tim-crazy.jpg/450px-Team-opoptosis-2016-tim-crazy.jpg" /> </div>
 +
</div>
 +
</div>
 +
<div class="cell-right">
 +
<h2> Tim Rapp </h2>
 +
<ul>
 +
<li> <strong>Nickname</strong>: Timmy </li>
 +
<li> <strong>Study Path</strong>: B.Sc. Biology Plus/International </li>
 +
<li> <strong>Hobbys</strong>: sports &amp; drawing </li>
 +
<li> <strong>Favorite Chemical</strong>: Chloroform </li>
 +
<li> <strong>Favorite Pokémon</strong>: Garbodor</li>
 +
<li> <strong>Favorite Beer</strong>: Jever </li>
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<li> <strong>Favorite Quote</strong>:“And so the lion fell in love with the lamb.” - Goethe </li>
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<div class="img-hidden"> <img src="https://static.igem.org/mediawiki/2016/thumb/c/c6/Team-opoptosis-2016-tobi-crazy.jpg/450px-Team-opoptosis-2016-tobi-crazy.jpg" /> </div>
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<h2> Tobias Link </h2>
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<li> <strong>Nickname</strong>: Picker </li>
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<li> <strong>Study Path</strong>: Biology </li>
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<li> <strong>Hobbys</strong>: football, fitness, gaming </li>
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<li> <strong>Favorite Chemical</strong>: Ethidiumbromid </li>
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<li> <strong>Favorite Pokémon</strong>: Venusaur </li>
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<li> <strong>Favorite Beer</strong>: Königpilsener </li>
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<li> <strong>Life Motto</strong>:He who says he can and he who says he can't are not usually right </li>
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<h2>Matias Zurbriggen</h2>
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no sea takimata sanctus est Lorem ipsum dolor sit amet.
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<h2 id="MLP">MLP-Career-Day </h2>
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<p>After asking them for help with our project, we were kindly invited to attend a Career-Day as a team by MLP Düsseldorf. They wanted to help improve our skills in presenting ourselves, achieving results as a group, make decisions in a group in a fast and effective manner and generally help getting to know each other better and learn about the strengths of the other team members.</p>
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<p>First, we invited them to come to one of our weekly meetings to learn about MLP and what they wanted to do for us. Two employees came to the meeting: Kenan Hadzihamzic and Dimitri Tzourmbakis. It was a very entertaining encounter and we immediately were very enthusiastic about their offer: To come visit them at the MLP-Branch in Düsseldorf to help us improve our soft skills.</p>
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<p>Then, on a Saturday morning, we all arrived at our destination and were welcomed hearty at their office building by Kenan, Dimitri and an additional employee that we met: Branko Beljak.
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At first, they helped us improve our ways of presenting ourselves, then we carried out an exercise to find an outcome as a short group in a short time efficiently: A situation, where we should choose the ideal candidate for a certain business was simulated. After that, a similar exercise was carried out but with a bigger group.
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<p>Finally, we took our lunch break: They bought pizza for the whole team! We had a very relaxing and nice time chatting and playing table football against the employees.</p>
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<p>After the break, we simulated a situation of a casino-trip, where we got to choose between an own big benefit or for the good of all: It was an exercise to test and improve our team spirit. We scored brilliant results, it was an important moment for all team members.</p>
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<p>At the end, we evaluated the day and the benefit it has brought to us and our project; The feedback by us and the employees was highly positive and everyone profited from it.</p>
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<p>Everyone that attended this Career-Day was given the chance to get some evaluation about their individual strengths and weaknesses and how to improve oneself based on that in a personal meeting with one of the three involved employees.</p>
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<p>We are glad that they gave us the opportunity to attend to this highly effective career day and help us to improve our project!</p>
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Revision as of 21:08, 18 October 2016


Heinrich-Heine University
Universitätsstraße 1
40225 Düsseldorf
Design by Marvin van Aalst

Our Team

Welcome to Optoptosis

Our group consists of 19 motivated undergraduate students, that came together in late 2015 to found the first iGEM Team of the Heinrich Heine University in Duesseldorf. In 2015 we made it our goal, to create a new and innovative application for synthetic biology and become a part of the renowned iGEM competition.
Already in the early stage of the project it was definite that we would emphasize on creating a mechanism to fight one of the deadliest diseases in the world: cancer. On this page we will tell you how we approach this big goal.