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− | <p> | + | <div class="container text_header"> <h1 style="margin-left:30px">Human Practice</h1></div> |
+ | <div class="container text_header"><h2 style="margin-left:30px">Meeting half way</h2></div> | ||
+ | <div class="container text_header"> <h3 style="margin-left:30px">Introduction</h3></div> | ||
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After we decided on Evobodies for our project in April we quickly learned the difficulty | After we decided on Evobodies for our project in April we quickly learned the difficulty | ||
of explaining our plans to others. Because binding proteins have major impacts on public life e.g. in pregnancy tests | of explaining our plans to others. Because binding proteins have major impacts on public life e.g. in pregnancy tests | ||
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closed laboratory doors. To breach this barrier, we engaged <b>on different frontiers</b>. | closed laboratory doors. To breach this barrier, we engaged <b>on different frontiers</b>. | ||
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− | + | <div class="container text_header"> <h3 style="margin-left:30px;">Language barrier</h3></div> | |
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Over the course of creating our Evobody generating system we experienced extreme difficulties explaining topics | Over the course of creating our Evobody generating system we experienced extreme difficulties explaining topics | ||
like "directed evolution" or "two hybrid system" to a non scientific auditorium. Our first presentation on our project | like "directed evolution" or "two hybrid system" to a non scientific auditorium. Our first presentation on our project | ||
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we learned that the language barrier between regular language and scientific terminology is known a major issue when communicating scientific topics. That is why | we learned that the language barrier between regular language and scientific terminology is known a major issue when communicating scientific topics. That is why | ||
we started several follow-up projects to breach this barrier: | we started several follow-up projects to breach this barrier: | ||
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We created a <a href="https://2016.igem.org/Team:Bielefeld-CeBiTec/HP/Dictionary"><b>dictionary</b></a> on synthetic biology to translate scientific language and especially Evobodies into regular english phrasing. | We created a <a href="https://2016.igem.org/Team:Bielefeld-CeBiTec/HP/Dictionary"><b>dictionary</b></a> on synthetic biology to translate scientific language and especially Evobodies into regular english phrasing. | ||
We collected over 500 terms from a lot of different scientific fields such as genome analysis and biotechnology, as well as topics like "biosafety" and others. | We collected over 500 terms from a lot of different scientific fields such as genome analysis and biotechnology, as well as topics like "biosafety" and others. | ||
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simple words when explaining their research to a public audience. | simple words when explaining their research to a public audience. | ||
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Another highlight of our summer was the <b>5th annual CeBiTec students academy</b>. Every year 20 | Another highlight of our summer was the <b>5th annual CeBiTec students academy</b>. Every year 20 | ||
ambitious high school students stay for one week at the CeBiTec to learn about recent research and collect | ambitious high school students stay for one week at the CeBiTec to learn about recent research and collect | ||
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scientific methods and techniques. This led to our third approach. | scientific methods and techniques. This led to our third approach. | ||
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− | <p style=width:45%>We transported the idea of directed evolution to human practice and started a <a href="https://2016.igem.org/Team:Bielefeld-CeBiTec/HP/School_Talks"><b>series of presentations</b></a> at high | + | <div class="container text"> <p style=width:45%>We transported the idea of directed evolution to human practice and started a <a href="https://2016.igem.org/Team:Bielefeld-CeBiTec/HP/School_Talks"><b>series of presentations</b></a> at high |
schools. After each session, we reflected on our presentation style and comprehensibility of certain parts | schools. After each session, we reflected on our presentation style and comprehensibility of certain parts | ||
in our construction. The results were quite surprising but gradually we were able to improve our presentation to enhance the | in our construction. The results were quite surprising but gradually we were able to improve our presentation to enhance the | ||
general understanding of Evobodies without prior scientific knowledge. | general understanding of Evobodies without prior scientific knowledge. | ||
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To involve the public in our fundraising campaign we started a <a href="https://2016.igem.org/Team:Bielefeld-CeBiTec/HP/Crowdfunding"><b>crowdfunding project</b></a> on Startnext.de. | To involve the public in our fundraising campaign we started a <a href="https://2016.igem.org/Team:Bielefeld-CeBiTec/HP/Crowdfunding"><b>crowdfunding project</b></a> on Startnext.de. | ||
The videoclip we created received very positive feedback and guaranteed the success of the campaign. Furthermore it explained | The videoclip we created received very positive feedback and guaranteed the success of the campaign. Furthermore it explained | ||
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We received almost instantly feedback through financial support and comments through social media. Our initial aim on | We received almost instantly feedback through financial support and comments through social media. Our initial aim on | ||
opening our project to a broader audience was just as successfully achieved as our monetary goal. | opening our project to a broader audience was just as successfully achieved as our monetary goal. | ||
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− | + | <div class="container text_header"> <h3>Expert consultation</h3></div> | |
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To analyze our project on a scientific level we further did our best to search for potential flaws or improvement | To analyze our project on a scientific level we further did our best to search for potential flaws or improvement | ||
in applicability and relevance of our system: | in applicability and relevance of our system: | ||
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We were highly ambitious in contacting the science community to discuss and reflect our project. | We were highly ambitious in contacting the science community to discuss and reflect our project. | ||
That is why we contacted a lot of <b>scientists from different fields</b> (e.g. virology and protein engeineering) | That is why we contacted a lot of <b>scientists from different fields</b> (e.g. virology and protein engeineering) | ||
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at the Cebitec Symposium to get in touch with other scientists in a uncomplicated way. | at the Cebitec Symposium to get in touch with other scientists in a uncomplicated way. | ||
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− | + | <div class="container text_header"> <h3>Process development</h3></div> | |
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To further examine how applicable our system is regarding manufacturing processes, we created a concept on how to apply our method of | To further examine how applicable our system is regarding manufacturing processes, we created a concept on how to apply our method of | ||
Evobody generation on a industrial level. We developed a <b>complete process</b> from start to finish about using our molecular biological techniques | Evobody generation on a industrial level. We developed a <b>complete process</b> from start to finish about using our molecular biological techniques | ||
on a up scaled level. | on a up scaled level. | ||
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− | <p> | + | <div class="container text_header"> <h3>Business plan</h3></div> |
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Based on the process development and the integrated modeling, we did around our project, a <b>business plan around Evobodies</b> was constructed. | Based on the process development and the integrated modeling, we did around our project, a <b>business plan around Evobodies</b> was constructed. | ||
In this plan we analyze not only applicability but also compare the parameters of our designed process to existing generation techniques | In this plan we analyze not only applicability but also compare the parameters of our designed process to existing generation techniques | ||
in binding protein producing industry. Furthermore we examined aspects regarding legal guidelines, tax law, accreditation and marketing. | in binding protein producing industry. Furthermore we examined aspects regarding legal guidelines, tax law, accreditation and marketing. | ||
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Revision as of 18:04, 14 October 2016
Human Practice
Meeting half way
Introduction
After we decided on Evobodies for our project in April we quickly learned the difficulty of explaining our plans to others. Because binding proteins have major impacts on public life e.g. in pregnancy tests we decided to spent a lot of time on elaborating new ways to explain and communicate Evobodies with non-scientific people as well as with experts from other fields. Additionally we were getting in close contact with scientists who would give us important information and interesting feedback on our project. In our oppinion a scientifically well executed project is exactly as important as the associated dialogue between scientists and the public. The more we spoke with people not related to science, the more we learned how difficult it is to understand what whitecoated people do behind the closed laboratory doors. To breach this barrier, we engaged on different frontiers.
Language barrier
Over the course of creating our Evobody generating system we experienced extreme difficulties explaining topics like "directed evolution" or "two hybrid system" to a non scientific auditorium. Our first presentation on our project was in April when we discussed the generation of Evobodies with scientific staff from the university of Bielefeld. Already in this early stage we experienced major issues when explaining the complex structure of our high speed evolution. Due to these difficulties we established dialogue with the cultural anthropologist Florian Helfer from Frankfurt, Germany. After a video conference we learned that the language barrier between regular language and scientific terminology is known a major issue when communicating scientific topics. That is why we started several follow-up projects to breach this barrier:
We created a dictionary on synthetic biology to translate scientific language and especially Evobodies into regular english phrasing. We collected over 500 terms from a lot of different scientific fields such as genome analysis and biotechnology, as well as topics like "biosafety" and others. This tool should support non-scientific people to understand science related media and give scientists the chance to find simple words when explaining their research to a public audience.
Another highlight of our summer was the 5th annual CeBiTec students academy. Every year 20 ambitious high school students stay for one week at the CeBiTec to learn about recent research and collect practical experience what it means to work in a molecular biology laboratory. We instructed experiments in the field of synthetic biology and organized a barbecue for recreation in the evening. Once again we learned the difficulties to summarize our complex evolution system in a few sentences and learned a lot about communicating scientific methods and techniques. This led to our third approach.
We transported the idea of directed evolution to human practice and started a series of presentations at high schools. After each session, we reflected on our presentation style and comprehensibility of certain parts in our construction. The results were quite surprising but gradually we were able to improve our presentation to enhance the general understanding of Evobodies without prior scientific knowledge.
To involve the public in our fundraising campaign we started a crowdfunding project on Startnext.de. The videoclip we created received very positive feedback and guaranteed the success of the campaign. Furthermore it explained in a very grafical way how our system works and where it can be applied. By showing how we are able to encounter natural evolution we wanted to retrieve public participation in our project. We received almost instantly feedback through financial support and comments through social media. Our initial aim on opening our project to a broader audience was just as successfully achieved as our monetary goal.
Expert consultation
To analyze our project on a scientific level we further did our best to search for potential flaws or improvement in applicability and relevance of our system:
We were highly ambitious in contacting the science community to discuss and reflect our project. That is why we contacted a lot of scientists from different fields (e.g. virology and protein engeineering) and discussed in a constant dialogue different aspects of our system. Especially Dr. Manel Camps from Santa Cruz University helped us a lot by answering our questions and giving us recommendations were to improve our project. We also attended different symposia to stay in touch with state of the art research and presented our poster at the Cebitec Symposium to get in touch with other scientists in a uncomplicated way.
Process development
To further examine how applicable our system is regarding manufacturing processes, we created a concept on how to apply our method of Evobody generation on a industrial level. We developed a complete process from start to finish about using our molecular biological techniques on a up scaled level.
Business plan
Based on the process development and the integrated modeling, we did around our project, a business plan around Evobodies was constructed. In this plan we analyze not only applicability but also compare the parameters of our designed process to existing generation techniques in binding protein producing industry. Furthermore we examined aspects regarding legal guidelines, tax law, accreditation and marketing.