Difference between revisions of "Team:UNebraska-Lincoln/Integrated Practices 4"

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<li style="font-weight: 400;"><span style="font-weight: 400;">Reliability of the BioBricks</span></li>
 
<li style="font-weight: 400;"><span style="font-weight: 400;">Reliability of the BioBricks</span></li>
 
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</ul>
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<h3 align="middle">Knockout Nitrate: Our serA Kill Switch Safety Case Diagram<h3>
 
<h3 align="middle">Knockout Nitrate: Our serA Kill Switch Safety Case Diagram<h3>
 
<img src="https://static.igem.org/mediawiki/2016/2/24/T--UNebraska-Lincoln--safetyCase1.png" align="middle" style="width:100%; height:auto; transform: scale(0.8)" alt="image"/>
 
<img src="https://static.igem.org/mediawiki/2016/2/24/T--UNebraska-Lincoln--safetyCase1.png" align="middle" style="width:100%; height:auto; transform: scale(0.8)" alt="image"/>

Revision as of 09:15, 19 October 2016

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Our Safety Case


The safety case we created will ideally serve as a model for other iGEM teams and set the precedent of how safety cases can be used as a safety platform for the iGEM competition. The scope of our safety case is limited to the serA kill switch.

Identified Environmental Hazards:

  • Bacterial Conjugation
  • Accidental Release
  • Natural Migration
  • Decomposition of biomass from dead E. coli cells
  • Gene products - serA
  • Reliability of the BioBricks

Knockout Nitrate: Our serA Kill Switch Safety Case Diagram

image

Click here to view the safety case in a text format 


*Briefly describe arguments in the safety case.


Our safety case is not perfect. Realistically no safety case applied to biology really can be. Since the scope of the iGEM project is limited due to time constraints, experimental results that validate the safety of systems in simulated environments may be hard to come by. In software engineering, when safety arguments are not fully developed, it is common practice to indicate this in the diagram with a diamond following any claim that cannot be supported with sufficient evidence.