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<h1><b>Gold Medal - Product Design</b></h1>
 
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<b>Background</b>
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<b>Gold Medal - <br> Insights from Tristable Switch</b>
 
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<p style="color: white; font-size: 1.2em;">Our circuit, the tri-stable switch, has many possible functions, ranging from bio-computing, cell differentiation to biosensors. This year, we decided to apply our tri-stable switch on something beneficial for the Hong Kong community, which is a biosensor for fungal diseases in trees. By using the tri-stable switch, the chemical which has the highest concentration out of three different target substances can be detected. When used as the tree biosensor, the switch will be used to detect tree wounds as well as two different kinds of fungi which live on the roots of trees. After detecting the presence of a fungus or a wound, the device will release chemicals that can either kill the parasite or heal the tree wounds. We plan to use Liana plants as a potential host for easier delivery of the device to the trees. We hope that this biosensor design would be able to help the Hong Kong Government in reducing accidents caused by falling trees. In the future, the circuit can  also be used to detect pests in plants grown in commercial farms.</p>
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<h2 class="text-center title"><b>1) Principle Behind Application: Tree diseases detector</b></h2>
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<p style="color: black; font-size: 1.2em;">The product is in the form of genetically engineered Liana plant. It will be planted near the target tree, enabling it to grow and climb up the tree without much care needed.
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After analysing the problems that iGEM teams usually encounter, we probe into our Tristable Switch to see how it can be applied to solve these existing problems. In the end, we think of some ways to assist the other iGEM teams. Although only some of them could be carried out at the time being, Tristable Switch could at least provide us with some ideas to resolve part of the current difficulties.
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<li>Normal Liana leaves are green-colored. However, when a wound is detected, the <b>Liana sap</b> close to it will turn <b>orange</b>. </li>
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For more information, please click <a href ="https://static.igem.org/mediawiki/2016/a/a5/IGEM2016_HKUST_insights.pdf" target="_blank">here</a>.
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<li>When there is a presence of <b>brown rot</b> fungi, the sap turns <b>red</b>.</li>
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<p style="color: black; font-size: 1.2em;">Finally, we cannot finish our project without helps from professors that we had interviewed during summer period. We really appreciate their time answering our questions through email, skype, or face to face interview. These are the name of the professors who assist us with human practices project:
 
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<li>Matthew R. Bennett, Ph.D.</li>
 
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Latest revision as of 03:27, 20 October 2016

Home

Gold Medal -
Insights from Tristable Switch

After analysing the problems that iGEM teams usually encounter, we probe into our Tristable Switch to see how it can be applied to solve these existing problems. In the end, we think of some ways to assist the other iGEM teams. Although only some of them could be carried out at the time being, Tristable Switch could at least provide us with some ideas to resolve part of the current difficulties.

For more information, please click here.


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