Difference between revisions of "Team:Hong Kong HKUST/HP/Silver"

 
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<b>Silver Medal - Intellectual Property Rights</b>
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<b>Silver Medal - <br>Difficulties iGEM teams <br>usually face</b>
 
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The tristable switch has previously been worked on by Brown University iGEM team in 2006 and 2007. Although the team did not complete their circuit construction, the idea was originally theirs. Hence, we ventured on an investigation based on articles and interviews with experts regarding academic originality. Some sources mentioned that our team is able to patent the invention as long as nobody has previously filed a patent application. Moreover, some patents are only applicable in the scope of a specific area, depending on the country in which the invention has been filed. We therefore might be able to patent tristable switch since Brown University is located in different country. Nonetheless, the idea has long been published on their iGEM wiki page - a public domain, resulting the invention to lose its novelty.  
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The International Genetically Engineered Machine (iGEM) competition is a renowned scientific event for the whole world which aims at promoting the systematic engineering of biology by constructing basic biological systems from standard and exchangeable parts obtained from cells. Generally, there are several common difficulties for the iGEM teams which would be hard to solve sometimes due to the knowledge-gap without a well-studied biological mechanism. Some of the examples are listed as follows:<br><br>
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<ul>1. Hard to define standardised biological parts.  
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Although the tristable switch is non-patentable, we can still patent the application of tristable switch as long as we have not uploaded or shared our application to a public domain. We however think that it is too early to do so as we have yet refined the complete designs for our application. Tristable switch has various applications, and beneficial functions are not just limited to biosensing. People can therefore develop tristable switch accordingly and claim rights when an appropriate application has been established.
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Absolute measures, standardised characterisation, have to be deployed in order to reduce the associated complexity of parts comparison.<br><br>
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2. Not available for predictable design procedures resulting in tedious trials and errors.
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Intellectual property rights are policies that protect owner’s right over their product through copyright, patents, and trademarks. Each of these rights plays a role in safeguarding property rights. For example, patents, a governmental grant that allows someone to protect an invention (Intellectual Property Office, 2016). In order to to respect the owners and to praise their creativity, intellectual property rights are highlighted in most of the developed countries. Though there are variations in the property rights nationally, they share the same goal. What if a country lacks a desirable system to secure owner's’ rights? It is likely that profound impacts would be imposed such as the economic decline and diminished reputation.
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The teams have to optimise the systems at all costs.<br><br>
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3. Hard to avoid unexpected cell-cell interactions.
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Biological machineries need to be insulated from the natural cell machineries as much as possible.<br><br>
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4. Hard to avoid variability and lift the stability of the system at the same time.</ul><br><br>
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We hope to have a brief investigation on the difficulties that iGEM teams would usually encountered to see if our Tristable Switch would be able to eradicate the problems. Making use of the advantages of that the Tristable Switch proceeds, for example, higher specificity, ultra stability and being toolkit-like, hopefully, iGEM teams could further improve their projects or be provided with alternatives. Difficulties that came across during biosensing are brought into focus owing to its popularity among iGEM teams.</p>
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<b><em>REFERENCES</em></b>
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<ol><li>Giese, B. (Ed.). (2014). <i>Synthetic Biology: Character and Impact; Edited by B. Giese, Christian Pade, H. Wigger, Armin Von Gleich. Christian Pade, H. Wigger, Armin Von Gleich. </i>Springer.</li>
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Obviously, everyone should act according to the intellectual property rights. However, considering the iGEM society, which is not as compact as a country, it is hard to determine if the system is the same as that of a country or not, since originality is always emphasized to treasure the creativity and efforts by each team. If a team established an idea, years later, another team improves it, and in the end, a company commercializes a brand new product based on that idea, how should we and the iGEM community take advantage of the intellectual property rights? As synthetic biology advances, this scenario would occur more frequently. Hoping to look into the field applications of the intellectual property rights, we would like to take our project as an example for further investigation.
 
  
 
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Latest revision as of 05:01, 3 November 2016

Home

Silver Medal -
Difficulties iGEM teams
usually face



The International Genetically Engineered Machine (iGEM) competition is a renowned scientific event for the whole world which aims at promoting the systematic engineering of biology by constructing basic biological systems from standard and exchangeable parts obtained from cells. Generally, there are several common difficulties for the iGEM teams which would be hard to solve sometimes due to the knowledge-gap without a well-studied biological mechanism. Some of the examples are listed as follows:

    1. Hard to define standardised biological parts. Absolute measures, standardised characterisation, have to be deployed in order to reduce the associated complexity of parts comparison.

    2. Not available for predictable design procedures resulting in tedious trials and errors. The teams have to optimise the systems at all costs.

    3. Hard to avoid unexpected cell-cell interactions. Biological machineries need to be insulated from the natural cell machineries as much as possible.

    4. Hard to avoid variability and lift the stability of the system at the same time.


We hope to have a brief investigation on the difficulties that iGEM teams would usually encountered to see if our Tristable Switch would be able to eradicate the problems. Making use of the advantages of that the Tristable Switch proceeds, for example, higher specificity, ultra stability and being toolkit-like, hopefully, iGEM teams could further improve their projects or be provided with alternatives. Difficulties that came across during biosensing are brought into focus owing to its popularity among iGEM teams.

REFERENCES

  1. Giese, B. (Ed.). (2014). Synthetic Biology: Character and Impact; Edited by B. Giese, Christian Pade, H. Wigger, Armin Von Gleich. Christian Pade, H. Wigger, Armin Von Gleich. Springer.