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− | <h2><a href="" title="abstract">Abstract</a></h2>
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− | Plastic pollution effects on our eco system is a major concern, damging our envoirment and causing harm to plants, animals and humans.
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− | As plastic exists only for about 100 years, evolution could not catch up and the natural biodegredtion is slow and inefficient meanwhile plastic has been massivly accumulating in nature.
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− | </p>
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− | We, the BGU iGEM team want to solve this problem combing tools of exerimental evolution, synthetic biology and computational biology.
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− | Using these tools we made three different approches to try and solve the problem:
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− | Serial passaging of the bacteria Rhodococcus ruber which has been found to bio-degrade plastic, we hope to enhance the ability of it to biodegrade using this tool.
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− | Raional mutation design - Using PROSS we aim to improve the catalytic activity of the enzyme LC-Cutinase which break down PET to terephthalate and ethylene glycol.
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− | Genetic engineering of metabolic pathways–we will modify two metabolic pathways using engineered enzymatic cascades which will be transformed into Pseudomonas putida
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− | <h4>Address:</h4>
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− | Ben-Gurion University of the Negev<br>
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− | Ben Gurion 1, Beer Sheva 8410501, Israel
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− | <b><u>Mail:</u> igembgu2016@gmail.com</b>
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− | <h4>Connect With Us!</h4>
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− | <h4>CopyRights</h4>
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