Team:Tokyo Tech/Modeling Overview

• 
• 
• 
  • 
    • 
    • 
    • 
    • 
  • 
    • 
    • 
    • 
  • 
  • 
    • 
    • 
• 
• 
  • 
  • 
  • 
  • 
• 
  • 
  • 
  • 
• 
• 
  • 
  • 
  • 
  • 
  • 
  • 

Model

Contents

1. Overview

2. Mathematical Model

3. Fitting

4. Analysis

5. Software

Overview

To reproduce the story of ”Snow White”, we have designed the cell-cell communication system with improved or characterized parts and collected data from comprehensive experiments. Furthermore, we constructed the mathematical model in order to simulate the behavior of the whole system and to confirm the feasibility of our story. This simulation successfully contributed to give the suggestions to wet lab experiments and confirm the feasibility of our system. In addition, in order to utilize TA (Toxin-Antitoxin) system, we developed a new software in Java for adjusting the number of ACA sequences, which MazF dimer recognizes and cleaves in mRNAs.

Mathematical Model

To simulate our gene circuits, we developed an ordinary differential equation model.

[Detailed Description for Modeling]

Read More

隠しスペース

Analysis

Lastly we got and verified the desirable behavior of the fluorescence by modifying and improving them. As described below, it is consistent with the development of story.

SOFTWARE

ACA Sequence: