Team:KAIT Japan/Collaborations
collaborations
-Modeling collaboration-
Our team collaborated with iGEM 2016 team Tokyo_Tech(Tokyo Institute of Technology).We requested help from them to create a mathematical model for our project. We felt so thankful to our collaborator for bring such strong contribution to our project.
In our project, we planned on increasing the production of Bacterial Cellulose (BC) produced by the bacteria A. xylinum. To increase the production of Bacteria Cellulose, we take the cellulose synthesis pathway into account.
 Concentrations without applying the antisense method
(b) Concentration while inhibiting G6PD enzyme
(c) Concentrations inhibiting PGI enzyme
(d) Concentrations inhibiting both G6PD and PGI enzymes
(e) Concentrations strongly inhibiting both enzymes
The graph above shows that the more we inhibit the enzymes G6PD and PGI, the more the production of BC increases. Therefore, we can assume this model is correct. However, we cannot assume that this is the most appropriate result since it has not been corroborated with the experiments.
At last, we would like to thank our collaborator (Tokyo_Tech) once again for helping us in our initial stage of our project.
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