Ariefpm13597 (Talk | contribs) |
Ariefpm13597 (Talk | contribs) |
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{{:Template:UI-Indonesia/css/menu_bar}} | {{:Template:UI-Indonesia/css/menu_bar}} | ||
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<html> | <html> | ||
<head> | <head> | ||
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.portfolio-box:focus { | .portfolio-box:focus { | ||
outline: none; | outline: none; | ||
+ | } | ||
+ | .button-learn-more{ | ||
+ | width: 225px; | ||
+ | height: 63px; | ||
+ | font-size: 24px; | ||
+ | color: white; | ||
+ | background: transparent; | ||
+ | border-radius: 8px; | ||
+ | border: 3px solid white; | ||
+ | font-weight: 600px; | ||
+ | cursor: pointer; | ||
+ | margin-bottom: 205px; | ||
+ | -webkit-transition-duration: 0.4s; | ||
+ | transition-duration: 0.4s; | ||
+ | } | ||
+ | .button-learn-more:hover{ | ||
+ | box-shadow: 0 12px 16px 0 rgba(0,0,0,0.24),0 17px 50px 0 rgba(0,0,0,0.19); | ||
} | } | ||
.button-ourproject-details{ | .button-ourproject-details{ | ||
− | width: | + | width: 225px; |
− | height: | + | height: 63px; |
font-size: 24px; | font-size: 24px; | ||
color: #E74C3C; | color: #E74C3C; | ||
background: transparent; | background: transparent; | ||
border-radius:8px; | border-radius:8px; | ||
− | border: | + | border: 3px solid #E74C3C; |
font-weight: 600px; | font-weight: 600px; | ||
margin-bottom: 205px; | margin-bottom: 205px; | ||
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} | } | ||
.button-medalcriteria-details{ | .button-medalcriteria-details{ | ||
− | width: | + | width: 225px; |
− | height: | + | height: 63px; |
font-size: 24px; | font-size: 24px; | ||
color: #E74C3C; | color: #E74C3C; | ||
background: transparent; | background: transparent; | ||
border-radius:8px; | border-radius:8px; | ||
− | border: | + | border: 3px solid #E74C3C; |
font-weight: 600px; | font-weight: 600px; | ||
margin-bottom: 205px; | margin-bottom: 205px; | ||
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} | } | ||
.button-team-details{ | .button-team-details{ | ||
− | width: | + | width: 225px; |
− | height: | + | height: 63px; |
font-size: 24px; | font-size: 24px; | ||
color: #E74C3C; | color: #E74C3C; | ||
background: transparent; | background: transparent; | ||
border-radius:8px; | border-radius:8px; | ||
− | border: | + | border: 3px solid #E74C3C; |
font-weight: 600px; | font-weight: 600px; | ||
margin-bottom: 205px; | margin-bottom: 205px; | ||
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.button-team-details:hover{ | .button-team-details:hover{ | ||
box-shadow: 0 12px 16px 0 rgba(0,0,0,0.24),0 17px 50px 0 rgba(0,0,0,0.19); | box-shadow: 0 12px 16px 0 rgba(0,0,0,0.24),0 17px 50px 0 rgba(0,0,0,0.19); | ||
+ | } | ||
+ | .button-general{ | ||
+ | margin-top: 25px; | ||
+ | width: 225px; | ||
+ | height: 63px; | ||
+ | font-size: 24px; | ||
+ | color: #E74C3C; | ||
+ | background: transparent; | ||
+ | border-radius:8px; | ||
+ | border: 3px solid #E74C3C; | ||
+ | font-weight: 600px; | ||
+ | margin-bottom: 205px; | ||
+ | cursor: pointer; | ||
+ | -webkit-transition-duration: 0.4s; | ||
+ | transition-duration: 0.4s; | ||
+ | } | ||
+ | .button-general:hover{ | ||
+ | box-shadow: 0 12px 16px 0 rgba(0,0,0,0.24),0 17px 50px 0 rgba(0,0,0,0.19); | ||
+ | } | ||
+ | .font-learn-more{ | ||
+ | color: white; | ||
+ | } | ||
+ | .parts-section{ | ||
+ | |||
+ | } | ||
+ | .imgHumanPractice{ | ||
+ | display: block; | ||
+ | margin: auto; | ||
+ | margin-top: 25px; | ||
+ | margin-bottom: 25px; | ||
+ | } | ||
+ | .imgHivax{ | ||
+ | display: block; | ||
+ | margin: auto; | ||
+ | margin-top: 25px; | ||
+ | margin-bottom: 25px; | ||
} | } | ||
</style><!-- header section --> | </style><!-- header section --> | ||
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<a href="#our-project">Our Project</a> | <a href="#our-project">Our Project</a> | ||
</li> | </li> | ||
− | <li> | + | <li class='has-sub'> |
− | <a href='https://2016.igem.org/ | + | <a href='#part-section'>Part</a> |
+ | <ul> | ||
+ | <li><a href="https://2016.igem.org/Team:UI-Indonesia/Basic_Part">Basic Part</a></li> | ||
+ | <li><a href="https://2016.igem.org/Team:UI-Indonesia/Parts">Part</a></li> | ||
+ | </ul> | ||
</li> | </li> | ||
<li> | <li> | ||
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<ul> | <ul> | ||
<li> | <li> | ||
− | <a href="https://2016.igem.org/Team:UI-Indonesia/HP/Silver"> | + | <a href="https://2016.igem.org/Team:UI-Indonesia/HP/Silver">Field Activities</a> |
</li> | </li> | ||
<li> | <li> | ||
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</li> | </li> | ||
<li> | <li> | ||
− | <a href="https://2016.igem.org/Team:UI-Indonesia/ | + | <a href="https://2016.igem.org/Team:UI-Indonesia/Integrated_Practices |
+ | ">Integrated Human Practice</a> | ||
</li> | </li> | ||
<li> | <li> | ||
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<li> | <li> | ||
<a href='#team'>Team</a> | <a href='#team'>Team</a> | ||
− | |||
− | |||
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</li> | </li> | ||
<li class='has-sub'> | <li class='has-sub'> | ||
− | <a href='# | + | <a href='#'>References</a> |
<ul> | <ul> | ||
<li> | <li> | ||
− | <a href=" | + | <a href="https://2016.igem.org/Team:UI-Indonesia/Notebook">Notebook</a> |
</li> | </li> | ||
<li> | <li> | ||
− | + | <a href='https://2016.igem.org/Team:UI-Indonesia/Attributions'>Attributions</a> | |
− | + | ||
− | + | ||
− | <a href='https://2016.igem.org/ | + | |
</li> | </li> | ||
<li> | <li> | ||
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<div class="row"> | <div class="row"> | ||
<h3></h3> | <h3></h3> | ||
− | <h1>UI iGEM TEAM 2016</h1><button class=" | + | <h1>UI iGEM TEAM 2016</h1><a href="#our-project"><button type="button" class="button-learn-more">LEARN MORE</button></a> |
<p></p> | <p></p> | ||
</div> | </div> | ||
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<div class="row"> | <div class="row"> | ||
<div class="col-md-8 col-md-offset-2 contents-heading"> | <div class="col-md-8 col-md-offset-2 contents-heading"> | ||
− | <h2>Our Project: Hi, Vax!</h2><img alt="Hi, Vax! Logo" height=" | + | <h2>Our Project: Hi, Vax!</h2><img alt="Hi, Vax! Logo" class="imgHivax" height="150" src="https://static.igem.org/mediawiki/2016/5/5b/UI-Indonesia_Logo_Project-Logo%282%29.png" width="300"> |
<p>HIV is one of the biggest health issues the world has ever faced, and although antiretroviral therapy (ART) has made it possible to prevent mortality in HIV patients, it has | <p>HIV is one of the biggest health issues the world has ever faced, and although antiretroviral therapy (ART) has made it possible to prevent mortality in HIV patients, it has | ||
several limitations, including the logistic and economic burden that arises from the need for lifelong treatment. To end HIV, we still need a cure. Today, the best hope for a cure | several limitations, including the logistic and economic burden that arises from the need for lifelong treatment. To end HIV, we still need a cure. Today, the best hope for a cure | ||
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</div> | </div> | ||
</div> | </div> | ||
− | </section><!-- | + | </section><!-- part section --> |
− | <section class="contents text-center" id=" | + | <section class="contents text-center" id="part-section"> |
<div class="container"> | <div class="container"> | ||
<div class="row"> | <div class="row"> | ||
<div class="col-md-8 col-md-offset-2 contents-heading"> | <div class="col-md-8 col-md-offset-2 contents-heading"> | ||
<h2>Parts</h2> | <h2>Parts</h2> | ||
− | + | <a class="portfolio-box" href="https://2016.igem.org/Team:UI-Indonesia/Basic_Part"><img alt="" class="img-responsive" src="https://static.igem.org/mediawiki/2016/f/f2/T--UI-Indonesia--Parts01_Thumbnail.jpg"> | |
<div class="portfolio-box-caption"> | <div class="portfolio-box-caption"> | ||
<div class="portfolio-box-caption-content"> | <div class="portfolio-box-caption-content"> | ||
<div class="project-category text-faded"> | <div class="project-category text-faded"> | ||
− | + | Basic Part | |
</div> | </div> | ||
<div class="project-name"> | <div class="project-name"> | ||
− | + | Basic Part | |
</div> | </div> | ||
</div> | </div> | ||
− | </div></a> <a class="portfolio-box" href=" | + | </div></a> <a class="portfolio-box" href="https://2016.igem.org/Team:UI-Indonesia/Parts"><img alt="" class="img-responsive" src="https://static.igem.org/mediawiki/2016/e/e2/T--UI-Indonesia--Parts02_Thumbnail.jpg"> |
<div class="portfolio-box-caption"> | <div class="portfolio-box-caption"> | ||
<div class="portfolio-box-caption-content"> | <div class="portfolio-box-caption-content"> | ||
<div class="project-category text-faded"> | <div class="project-category text-faded"> | ||
− | + | Parts | |
</div> | </div> | ||
<div class="project-name"> | <div class="project-name"> | ||
− | + | Parts | |
</div> | </div> | ||
</div> | </div> | ||
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<div class="col-md-8 col-md-offset-2 contents-heading"> | <div class="col-md-8 col-md-offset-2 contents-heading"> | ||
<h2>Modelling</h2> | <h2>Modelling</h2> | ||
− | < | + | <a href="https://2016.igem.org/Team:UI-Indonesia/Model"><button type="button" class="button-general">Check This Out!</button></a> |
</div> | </div> | ||
</div> | </div> | ||
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<div class="col-md-8 col-md-offset-2 contents-heading"> | <div class="col-md-8 col-md-offset-2 contents-heading"> | ||
<h2>Human Practice</h2> | <h2>Human Practice</h2> | ||
− | <p> | + | <img src="https://static.igem.org/mediawiki/2016/a/a2/T--UI-Indonesia--3.png" width="640px" height="640px" class="img-responsive imgHumanPractice"> |
+ | <p>Wanna know more about the fun and madness in our 8 months projects? Only one click away to figure out the whole journey! Make sure to go to every tab on human practice section, fellas!</p> | ||
</div> | </div> | ||
</div> | </div> | ||
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<h2>Medal Criteria</h2> | <h2>Medal Criteria</h2> | ||
<p>"Go get gold" was our jargon. We did our best to achive every particular things in medal criteria.</p> | <p>"Go get gold" was our jargon. We did our best to achive every particular things in medal criteria.</p> | ||
− | </div><a href=" | + | </div><a href="https://2016.igem.org/Team:UI-Indonesia/Medal_Criteria"><button class="button-medalcriteria-details" type="button">Click here to know what we've done</button></a> |
</div> | </div> | ||
</div> | </div> | ||
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</div> | </div> | ||
</div> | </div> | ||
− | </div | + | </div><!-- footer starts here --> |
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<!-- script tags | <!-- script tags | ||
============================================================= --> | ============================================================= --> |
Latest revision as of 01:59, 20 October 2016
Our Project: Hi, Vax!
HIV is one of the biggest health issues the world has ever faced, and although antiretroviral therapy (ART) has made it possible to prevent mortality in HIV patients, it has several limitations, including the logistic and economic burden that arises from the need for lifelong treatment. To end HIV, we still need a cure. Today, the best hope for a cure is DNA vaccines, which are DNA molecules that harbour a gene encoding an antigen. When administered, cells will take up these molecules and produce the antigen. Dendritic cells will take this antigen to lymph nodes and present them to T cells, activating them and licensing them to hunt and kill infected cells. In theory, this would allow for the elimination of viral reservoir in the body. In reality, however, DNA vaccination for HIV hasn’t worked in humans.
Although the key component of a DNA vaccine is the antigen-encoding gene, the vaccine backbone, as the name implies, accounts for most of its mass and governs its activity. So, we wondered, can we design a better vaccine backbone? We have designed genetic elements that, when put together, will hopefully achieve improved transgene expression (promoter, intron, polyadenylation sequence and barrier element) and immune stimulation (immunostimulatory DNA motif and RNA gene as well as coding sequences for peptides that direct antigen processing) with respect to existing vaccine backbones. We’re having the parts synthesized and assembling them soon. We hope that this new vaccine backbone will give rise to new, safer and more potent DNA vaccines for HIV—maybe even a cure.
Human Practice
Wanna know more about the fun and madness in our 8 months projects? Only one click away to figure out the whole journey! Make sure to go to every tab on human practice section, fellas!
Result
Ready to start your next project with us? That's great! Give us a call or send us an email and we will get back to you as soon as possible!