Difference between revisions of "Team:Virginia"

 
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width:1200px;
 
width:1200px;
 
text-align:center;
 
text-align:center;
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height:150px;
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height:240px;
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background-color:white;
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margin: -1px auto 15px auto;
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}
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    .homeimagearea2 {
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width:1200px;
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text-align:center;
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height:600px;
 
background-color:white;
 
background-color:white;
 
margin: -1px auto 15px auto;
 
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}
 
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text-align:center;
 
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}
 
}
  
 
/*Box for content on page*/
 
/*Box for content on page*/
 
.content1 {
 
.content1 {
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width:1200px;
 
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#introvideobkg {
 
#introvideobkg {
 
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height:368px;
 
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box-shadow:1px 1px 3px #80ccff;
 
 
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#introvideo video {
 
#introvideo video {
 
display:block;
 
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background-image:url("https://static.igem.org/mediawiki/2016/e/e5/T--Virginia--vidposter.jpeg");
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background-image:url("https://static.igem.org/mediawiki/igem.org/2/20/T--Virginia--bc_videopic.png");
 
background-size:569px 320px;
 
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font-family:Lato, sans-serif;
 
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}
 
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margin-left:6px;  /*Automatic 4px space generated between inline-block elements*/
 
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background-image:url('https://static.igem.org/mediawiki/2016/f/fd/T--Virginia--teamphoto.jpeg');
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#stripe2 {
 
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#back1, #back2, #back3, #back4, #back5 {
 
#back1, #back2, #back3, #back4, #back5 {
 
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#back1 {
 
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background-image:url(https://static.igem.org/mediawiki/2016/e/e2/T--Virginia--labpic1.jpeg);
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}
 
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#back5 {
 
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background-image:url(https://static.igem.org/mediawiki/2016/1/12/T--Virginia--labpic5.jpeg);
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#homepagefadein1 a, #homepagefadein2 a  {
 
#homepagefadein1 a, #homepagefadein2 a  {
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font-family:Lato, sans-serif;
 
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}
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<!---------------------------Top image on page------------------------------------------>
 
<!---------------------------Top image on page------------------------------------------>
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<div class="homeimagearea" style="background-color:#ffa366">
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<div class="homeimagearea">
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<h1 style="line-height:100px">LEU-LOCK</h1>
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<img src = "https://static.igem.org/mediawiki/2016/6/68/T--Virginia--STC_cover.png">
 
</div>
 
</div>
  
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<!---------------------------Main content section of page------------------------------->
 
<!---------------------------Main content section of page------------------------------->
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<div class="content1">
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 +
 
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<div class="content1">
 
<div id="introvideobkg">
 
<div id="introvideobkg">
 
<div id="introvideo">
 
<div id="introvideo">
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</video>
 
</video>
 
</div>
 
</div>
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<span id="vidcap"><i>Want to learn more about synthetic biology? Click <a href="">here</a>.</i></span>
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<span id="vidcap"><i>Want to learn more about synthetic biology? Click <a href="https://2016.igem.org/Team:Virginia/Public_Education" style="color:#ffec7b">here</a>.</i></span>
 
</div>
 
</div>
  
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</span></p>
 
</span></p>
 
</div>
 
</div>
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<a href="https://2016.igem.org/Team:Virginia/Team" target="_blank">More about the team &rarr;</a>
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<a href="https://2016.igem.org/Team:Virginia/Team">More about the team &rarr;</a>
 
</div>
 
</div>
 
</div>
 
</div>
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<div id="homepagefadein2">
 
<div id="homepagefadein2">
 
<div id="fadeintext2">
 
<div id="fadeintext2">
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<h1>Leu-Lock</h1>
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<h1>Synthetic Translational Control</h1>
 
<p><span class="p">We set out to design a novel biocontainment mechanism based upon the modification of the leucyl tRNA synthetase enzyme.  
 
<p><span class="p">We set out to design a novel biocontainment mechanism based upon the modification of the leucyl tRNA synthetase enzyme.  
 
Our system causes the biocontained organism to be dependent upon a synthetic form of leucine for survival -  
 
Our system causes the biocontained organism to be dependent upon a synthetic form of leucine for survival -  
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hence the title of our project. To implement the system in <i>E. coli</i>, CRISPR Cas9 was used to knockout the native  
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hence the title of our project. To implement the system in <i>E. coli</i>, our goal was used to knockout the native  
−
<i>E. coli</i> tRNA synthetase gene, and the modified synthetase gene was inserted into the bacterial cells.
+
<i>E. coli</i> tRNA synthetase gene, and insert the modified synthetase gene into the bacterial cells.
 
</span></p>
 
</span></p>
 
</div>
 
</div>
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<a href="https://2016.igem.org/Team:Virginia/Description">Project Overview &rarr;<a/>
+
                    <a href="https://2016.igem.org/Team:Virginia/Description">Project Overview &rarr;</a>
 
</div>
 
</div>
 
</div>
 
</div>

Latest revision as of 03:38, 20 October 2016

Want to learn more about synthetic biology? Click here.

WHO ARE WE?

We are a team of undergraduate students from the University of Virginia with a shared interest in synthetic biology. We hail from five different states, and our majors include biology, biochemistry, chemical engineering, biomedical engineering, neuroscience, statistics, and nanomedicine engineering.

More about the team →

THE PROJECT

Synthetic Translational Control

We set out to design a novel biocontainment mechanism based upon the modification of the leucyl tRNA synthetase enzyme. Our system causes the biocontained organism to be dependent upon a synthetic form of leucine for survival - hence the title of our project. To implement the system in E. coli, our goal was used to knockout the native E. coli tRNA synthetase gene, and insert the modified synthetase gene into the bacterial cells.

Project Overview →