<!DOCTYPE html> Biology

PRACTICE

HUMAN PRACTICES

Abstract

This year our project is about the early detection of breast cancer based on the factors miRNA155 and miRNA21. In the last six months, things we have done were as follow: make a questionnaire aimed at surveying the public perceptions for breast cancer; make a survey to get the information about the diagnosis condition of breast cancer; introduce iGEM and the project of our team in a college and a high school. Besides, we have built relationship with five teams and had a interactive communication with other two teams, and also joined two different communication meetings during the summer vacation, which we had got many appreciation and comments.

Questionnaire

This year we issued the questionnaire through the Internet, with both Chinese and English versions and got information after collecting them. The questions were centered on the personal health, physical examination, the understanding of breast cancer and the team’s products. It was distributed online in January and ended in March and we received 299 valid feedbacks.

Survey

PARTⅠ Identity information

Q1. What is your gender?

A. Male
B. Female

Q2. How old are you?

A. Below20
B. 21-30
C. 31-40
D. Above41

Q3. What is your record of formal schooling?*

A. Junior high school
B. High school
C. College
D. Undergraduate or over it

Q4. Have you been married?*

A. YES
B. NO

Q5. What is your salary each month?*

A. ￥0
B. ￥0-3000
C. ￥3000-10000
D. Above￥10000

Q6. Is the field you are engaged in is connected to the biological?*

A. YES
B. NO

Q7. How much do you cost each month?*

A. Below￥1000
B. ￥1000-2000
C. ￥2000-3000
D. Above￥3000

Q8. Have you bought social security or medical insurance?*

A. YES
B. NO

PART Ⅱ Physical condition

Q9. What is your figure?*

A. Thin
B. Normal
C. Fat

Q10. What is your physical quality?*

A. Bad
B. Normal
C. Well

Q11. How often do you do exercise each week?*

A. Never
B. 1-2times
C. Above 3 times

Q12. Why do you exercise?*

A. For hobby
B. Someone organize
C. Keep fit

Q13. How long do you exercise each time?*

A. 10-20minutes
B. 20-30minutes
C. Above30minutes

Q14.Have you ever had significant medical history?*

A. YES
B. NO

Q15.When do you go to bed?*

A. Before10:00P.M
B. 10:00P.M-12:00P.M
C. After12:00P.M

Q16. Have you ever smoked or drunk?*

A. Neither
B. Smoked
C. Drunk
D. Both

Q17. Do you have breakfast?*

A. Never
B. Sometimes
C. Always
D. Everyday

PART Ⅲ About medical

Q18.How often do you do a physical examination ?*

A. Every year
B. Not regular
C. Never

Q19. What do you think about the price of medical?*

A. Expensive
B. Normal
C. Cheap

Q20. What is the meaning of medical?*

A. Predict
B. Check disease
C. Other

Q21. Can you understand the medical report?*

A. YES
B. NO

PART Ⅳ About breast cancer

Q22.Which way do you use to know about breast cancer?*(multiple choice)

A. Newspaper and magazine
B. Television and radio
C. Healthy classroom
D. The Internet
E. From doctor
F. Other

Q23. Which important factors do you think will induce breast cancer?*(multiple choice)

A. Female
B. Over 50 years old
C. Immediate family member shave medical history of breast cancer
D. Superior living condition
E. Delay menopause
F. Fatter after menopause
G. Have medical history of breast cancer
H. Have medical history of ovarian cancer
I. Have atypical hyper plastic benign breast disease
J. Amount of alcohol
K. Have menstruation before 12 years old
L. Have hormone replacement therapy

Q24. Which factors do you think will increase the risk of breast cancer?*(multiple choice)

A. Closed relative has breast cancer
B. Has breast cancer of other cancer
C. Hyperplasia of mammary glands for a long time
D. Endocrine disorders for a long time

Q25. Which sign do you think is danger for breast cancer?*(multiple choice)

A. Find lump in the breast
B. Breast hyperplasia increase happened in woman over 30 years old
C. Breast reduction and nipple up
D. Have ulcer around breast or nipple
E. Within the breast skin to shrink
F. Nipple have hemorrhagic discharge
G. Axillary lymph node enlargement

Q26.Do you know how to check breast by yourself?*

○A. YES
○B. No

Q27. What is the best way to treat breast cancer in the early?*

A. Surgery
B. Radiation therapy
C. Chemotherapy
D. Endocrine therapy
E. Immunotherapy
F. Chinese medicine for therapy

Q28. How often do you think to have a mammary gland film making check?*

A. Once a month
B. Three months
C. Half a year
D. Once a year
E. Two years

Q29. Do you know about Synthetic biology?*

A. YES
B. NO

Q30. Would you mind doing treatment in vitro with harmless microbial?*

A. YES
B. Never mind
C. No

Q31. How much do you think is suitable for a medical?*

A. Below￥500
B. ￥500-1000
C. Above￥1000

Q32. Which price is reasonable for our device?

A. ￥100-500
B. ￥500-1000
C. ￥1000-1500
D. Above￥1500

Q33. Do you have some requirements about product performance?*(multiple choice)

A. The use of intelligence
B. Date visualization
C. To detect the rapidness
D. The operation is simple
E. Repeat use

Q34. Would you like to use our product?*

A. YES
B. No

Survey in Hospital

Time:2016.10.12
Personnel: Yang Wei, Xiao Wenrui, Chen Daoying, Li Rui, Chen Minze, Li Anyi

In the preliminary design work of practical part, team members communicated the ideas of project with Doctor. Cao Tianyu who has 20 years’ experience of clinical treatment of breast cancer. First he gave highly appreciation of the project and agreed with the fields of quickly and accurately detection of diseases. Then he explained the breast cancer through pathogenesis, treatment method and incidence trend and put forward the constructive suggestion to the market application of the project. In general, he thought the project would have great application prospect.

In October five members had a face-to-face communication with Dr. Cao in the office. The five members showed the project to Dr. Cao and introduce the method of determination in detail. After the communication he gave some useful advice not only in biological part but also for the hardware and software. In part of biology, the accuracy of detection should be improved and whether can the public accept the method of biological detection or not still remains a question. For part of hardware, the hardware needs to find its strengths and improve it in order to complete with the existing instruments like Microplate Reader. In addition, there will be a long time for the hardware to apply in the clinic field. As for part of software: the interface of application need to be more friendly to doctors who use it to communicate with patients.

Figure: BIT members and Dr.Cao

Figure: At 309 hospital

Project Promotion in Schools

Time: 2016.09.22
Personnel: Wang Xu , Yang HaoKun, Zeng Qingquan, Li Anyi

On September 22, we had a preach in high school affiliated to BIT. The main content was to introduce Synthetic biology, let students know more about the emerging field of biological, present biological technology and also introduce something about iGEM. During the Q&A time the students asked many questions about the biological and synthetic biology and we believed that most of them had interests in this subject.

Figure: A group photo with classmates

Figure: At 309 hospital

On September 23 we, together with BIT-CHINA held a session for the class of 2016 undergraduates in Beijing Institute of Technology. Because most of the students’ knowledge of biology was just stayed at the stage of high school, the whole session was on the basis of synthetic biology knowledge and then extended to the projects of two IGEM teams. Before the beginning of session, we distributed the leaflets which included brief introduction of our project to the students. The whole session lasted almost two hours and had great feedback.

Figure: A group photo with classmates

Figure: YANG WEI is explaining the synthetic biology

Figure: leaflets

The two sessions in different schools we not only introduced of our team’s project, but also the concept of synthetic biology to more people. We aimed to let more people who are full of ideas and innovation consciousness dare to fight with themselves and take part in this competition with their energy. During the Q&A time the students put forward many questions which help two teams to improve their project. Thanks for the support of teachers and students.

Contact Us

Address

Beijing Institute of Technology,
No. 5 South Zhong Guan Cun Street,
Haidian Beijing 100081, P. R. China

Twitter : @igem_BIT

Sina Weibo : @igem_BIT

Website : http://www.bit.edu.cn

Team:BIT/Human Practices